Jitindra Fartiyal

Jitindra Fartiyal, Pedro Freire, Yasmeen Whayeb et al.

Medical imaging plays a critical role in modern healthcare, enabling clinicians to accurately diagnose diseases and develop effective treatment plans. However, noise, often introduced by imaging devices, can degrade image quality, leading to misinterpretation and compromised clinical outcomes. Existing denoising approaches typically rely either on noise characteristics or on contextual information from the image. Moreover, they are commonly developed and evaluated for a single imaging modality and noise type. Motivated by Geng et.al CNCL, which integrates both noise and context, this study introduces a Dual-Pathway Learning (DPL) model architecture that effectively denoises medical images by leveraging both sources of information and fusing them to generate the final output. DPL is evaluated across multiple imaging modalities and various types of noise, demonstrating its robustness and generalizability. DPL improves PSNR by 3.35% compared to the baseline UNet when evaluated on Gaussian noise and trained across all modalities. The code is available at 10.5281/zenodo.15836053.

Jitindra Fartiyal, Pedro Freire, Sergei K. Turitsyn et al.

Medical images are essential for diagnosis, treatment planning, and research, but their quality is often degraded by noise from low-dose acquisition, patient motion, or scanner limitations, affecting both clinical interpretation and downstream analysis. Traditional filtering approaches often over-smooth and lose fine anatomical details, while deep learning methods, including CNNs, GANs, and transformers, may struggle to preserve such details or require large, computationally expensive models, limiting clinical practicality. We propose PatchDenoiser, a lightweight, energy-efficient multi-scale patch-based denoising framework. It decomposes denoising into local texture extraction and global context aggregation, fused via a spatially aware patch fusion strategy. This design enables effective noise suppression while preserving fine structural and anatomical details. PatchDenoiser is ultra-lightweight, with far fewer parameters and lower computational complexity than CNN-, GAN-, and transformer-based denoisers. On the 2016 Mayo Low-Dose CT dataset, PatchDenoiser consistently outperforms state-of-the-art CNN- and GAN-based methods in PSNR and SSIM. It is robust to variations in slice thickness, reconstruction kernels, and HU windows, generalizes across scanners without fine-tuning, and reduces parameters by ~9x and energy consumption per inference by ~27x compared with conventional CNN denoisers. PatchDenoiser thus provides a practical, scalable, and computationally efficient solution for medical image denoising, balancing performance, robustness, and clinical deployability.