Deborah Volpe

Antonio Tudisco, Deborah Volpe, Giacomo Orlandi et al.

The growing variety of quantum hardware technologies, each with unique peculiarities such as connectivity and native gate sets, creates challenges when selecting the best platform for executing a specific quantum circuit. This selection process usually involves a brute-force approach: compiling the circuit on various devices and evaluating performance based on factors such as circuit depth and gate fidelity. However, this method is computationally expensive and does not scale well as the number of available quantum processors increases. In this work, we propose a Graph Neural Network (GNN)-based predictor that automates hardware selection by analyzing the Directed Acyclic Graph (DAG) representation of a quantum circuit. Our study evaluates 498 quantum circuits (up to 27 qubits) from the MQT Bench dataset, compiled using Qiskit on four devices: three superconducting quantum processors (IBM-Kyiv, IBM-Brisbane, IBM-Sherbrooke) and one trapped-ion processor (IONQ-Forte). Performance is estimated using a metric that integrates circuit depth and gate fidelity, resulting in a dataset where 93 circuits are optimally compiled on the trapped-ion device, while the remaining circuits prefer superconducting platforms. By exploiting graph-based machine learning, our approach avoids extracting the circuit features for the model evaluation but directly embeds it as a graph, significantly accelerating the optimal target decision-making process and maintaining all the information. Experimental results prove 94.4% accuracy and an 85.5% F1 score for the minority class, effectively predicting the best compilation target. The developed code is publicly available on GitHub (https://github.com/antotu/GNN-Model-Quantum-Predictor).

Andrea Grimaldi, Christian Duffee, Eleonora Raimondo et al.

Extremely large-scale multiple-input multiple-output (XL-MIMO) architectures are a key enabler of forthcoming 6G wireless communication networks by allowing high data rates through massive spatial multiplexing. Here, we approach these problems with physics-inspired unconventional computing based on Ising machines (IMs). For binary modulation, probabilistic IMs (PIMs) and oscillator-based IMs achieve optimal ML detection with systems up to 2048x2048 antennas with only 100 iterations, matching optimal sphere decoder performance for computationally treatable sizes and outperforming the minimum mean-square error (MMSE) industrial standard. For M-QAM up to 256, a generalized PIM-inspired framework, based on d-dimensional probabilistic variables (p-dits) that directly encode QAM symbols, shows low bit-error-rate across sizes up to 256x256 antennas, outperforming or matching MMSE with reduced algorithmic complexity. Unlike the binary mapping, the p-dit interaction matrix is independent of the QAM order, enabling adaptive MIMO modulation. These results show a promising scalable paradigm for XL MIMO detection in future 6G networks.

Antonio Tudisco, Deborah Volpe, Giovanna Turvani

Effective and accurate diagnosis of diseases such as cancer, diabetes, and heart failure is crucial for timely medical intervention and improving patient survival rates. Machine learning has revolutionized diagnostic methods in recent years by developing classification models that detect diseases based on selected features. However, these classification tasks are often highly imbalanced, limiting the performance of classical models. Quantum models offer a promising alternative, exploiting their ability to express complex patterns by operating in a higher-dimensional computational space through superposition and entanglement. These unique properties make quantum models potentially more effective in addressing the challenges of imbalanced datasets. This work evaluates the potential of quantum classifiers in healthcare, focusing on Quantum Neural Networks (QNNs) and Quantum Support Vector Machines (QSVMs), comparing them with popular classical models. The study is based on three well-known healthcare datasets -- Prostate Cancer, Heart Failure, and Diabetes. The results indicate that QSVMs outperform QNNs across all datasets due to their susceptibility to overfitting. Furthermore, quantum models prove the ability to overcome classical models in scenarios with high dataset imbalance. Although preliminary, these findings highlight the potential of quantum models in healthcare classification tasks and lead the way for further research in this domain.

Antonio Tudisco, Deborah Volpe, Giovanna Turvani

Accurate and reliable diagnosis of diseases is crucial in enabling timely medical treatment and enhancing patient survival rates. In recent years, Machine Learning has revolutionized diagnostic practices by creating classification models capable of identifying diseases. However, these classification problems often suffer from significant class imbalances, which can inhibit the effectiveness of traditional models. Therefore, the interest in Quantum models has arisen, driven by the captivating promise of overcoming the limitations of the classical counterpart thanks to their ability to express complex patterns by mapping data in a higher-dimensional computational space.