Yew Kee Wong

Yifan Zhou, Yan Shing Liang, Yew Kee Wong et al.

The Research & Development (R&D) phase of drug development is a lengthy and costly process. To revolutionize this process, we introduce our new concept QMLS to shorten the whole R&D phase to three to six months and decrease the cost to merely fifty to eighty thousand USD. For Hit Generation, Machine Learning Molecule Generation (MLMG) generates possible hits according to the molecular structure of the target protein while the Quantum Simulation (QS) filters molecules from the primary essay based on the reaction and binding effectiveness with the target protein. Then, For Lead Optimization, the resultant molecules generated and filtered from MLMG and QS are compared, and molecules that appear as a result of both processes will be made into dozens of molecular variations through Machine Learning Molecule Variation (MLMV), while others will only be made into a few variations. Lastly, all optimized molecules would undergo multiple rounds of QS filtering with a high standard for reaction effectiveness and safety, creating a few dozen pre-clinical-trail-ready drugs. This paper is based on our first paper, where we pitched the concept of machine learning combined with quantum simulations. In this paper we will go over the detailed design and framework of QMLS, including MLMG, MLMV, and QS.

Yifan Zhou, Chong Cheng Xu, Mingi Song et al.

This paper explores the transformative potential of quantum computing in the realm of personalized learning. Traditional machine learning models and GPU-based approaches have long been utilized to tailor educational experiences to individual student needs. However, these methods face significant challenges in terms of scalability, computational efficiency, and real-time adaptation to the dynamic nature of educational data. This study proposes leveraging quantum computing to address these limitations. We review existing personalized learning systems, classical machine learning methods, and emerging quantum computing applications in education. We then outline a protocol for data collection, privacy preservation using quantum techniques, and preprocessing, followed by the development and implementation of quantum algorithms specifically designed for personalized learning. Our findings indicate that quantum algorithms offer substantial improvements in efficiency, scalability, and personalization quality compared to classical methods. This paper discusses the implications of integrating quantum computing into educational systems, highlighting the potential for enhanced teaching methodologies, curriculum design, and overall student experiences. We conclude by summarizing the advantages of quantum computing in education and suggesting future research directions.