Sanjeev V. Namjoshi

2papers

2 Papers

LGOct 23, 2023
Serverless Federated Learning with flwr-serverless

Sanjeev V. Namjoshi, Reese Green, Krishi Sharma et al.

Federated learning is becoming increasingly relevant and popular as we witness a surge in data collection and storage of personally identifiable information. Alongside these developments there have been many proposals from governments around the world to provide more protections for individuals' data and a heightened interest in data privacy measures. As deep learning continues to become more relevant in new and existing domains, it is vital to develop strategies like federated learning that can effectively train data from different sources, such as edge devices, without compromising security and privacy. Recently, the Flower (\texttt{Flwr}) Python package was introduced to provide a scalable, flexible, and easy-to-use framework for implementing federated learning. However, to date, Flower is only able to run synchronous federated learning which can be costly and time-consuming to run because the process is bottlenecked by client-side training jobs that are slow or fragile. Here, we introduce \texttt{flwr-serverless}, a wrapper around the Flower package that extends its functionality to allow for both synchronous and asynchronous federated learning with minimal modification to Flower's design paradigm. Furthermore, our approach to federated learning allows the process to run without a central server, which increases the domains of application and accessibility of its use. This paper presents the design details and usage of this approach through a series of experiments that were conducted using public datasets. Overall, we believe that our approach decreases the time and cost to run federated training and provides an easier way to implement and experiment with federated learning systems.

IVOct 7, 2021
A transformer-based deep learning approach for classifying brain metastases into primary organ sites using clinical whole brain MRI

Qing Lyu, Sanjeev V. Namjoshi, Emory McTyre et al.

Treatment decisions for brain metastatic disease rely on knowledge of the primary organ site, and currently made with biopsy and histology. Here we develop a novel deep learning approach for accurate non-invasive digital histology with whole-brain MRI data. Our IRB-approved single-site retrospective study was comprised of patients (n=1,399) referred for MRI treatment-planning and gamma knife radiosurgery over 21 years. Contrast-enhanced T1-weighted and T2-weighted Fluid-Attenuated Inversion Recovery brain MRI exams (n=1,582) were preprocessed and input to the proposed deep learning workflow for tumor segmentation, modality transfer, and primary site classification into one of five classes. Ten-fold cross-validation generated overall AUC of 0.878 (95%CI:0.873,0.883), lung class AUC of 0.889 (95%CI:0.883,0.895), breast class AUC of 0.873 (95%CI:0.860,0.886), melanoma class AUC of 0.852 (95%CI:0.842,0.862), renal class AUC of 0.830 (95%CI:0.809,0.851), and other class AUC of 0.822 (95%CI:0.805,0.839). These data establish that whole-brain imaging features are discriminative to allow accurate diagnosis of the primary organ site of malignancy. Our end-to-end deep radiomic approach has great potential for classifying metastatic tumor types from whole-brain MRI images. Further refinement may offer an invaluable clinical tool to expedite primary cancer site identification for precision treatment and improved outcomes.