Simon Reiß

Jiaming Zhang, Kailun Yang, Chaoxiang Ma et al.

Panoramic images with their 360-degree directional view encompass exhaustive information about the surrounding space, providing a rich foundation for scene understanding. To unfold this potential in the form of robust panoramic segmentation models, large quantities of expensive, pixel-wise annotations are crucial for success. Such annotations are available, but predominantly for narrow-angle, pinhole-camera images which, off the shelf, serve as sub-optimal resources for training panoramic models. Distortions and the distinct image-feature distribution in 360-degree panoramas impede the transfer from the annotation-rich pinhole domain and therefore come with a big dent in performance. To get around this domain difference and bring together semantic annotations from pinhole- and 360-degree surround-visuals, we propose to learn object deformations and panoramic image distortions in the Deformable Patch Embedding (DPE) and Deformable MLP (DMLP) components which blend into our Transformer for PAnoramic Semantic Segmentation (Trans4PASS) model. Finally, we tie together shared semantics in pinhole- and panoramic feature embeddings by generating multi-scale prototype features and aligning them in our Mutual Prototypical Adaptation (MPA) for unsupervised domain adaptation. On the indoor Stanford2D3D dataset, our Trans4PASS with MPA maintains comparable performance to fully-supervised state-of-the-arts, cutting the need for over 1,400 labeled panoramas. On the outdoor DensePASS dataset, we break state-of-the-art by 14.39% mIoU and set the new bar at 56.38%. Code will be made publicly available at https://github.com/jamycheung/Trans4PASS.

Jiaming Zhang, Kailun Yang, Hao Shi et al.

In this paper, we address panoramic semantic segmentation which is under-explored due to two critical challenges: (1) image distortions and object deformations on panoramas; (2) lack of semantic annotations in the 360° imagery. To tackle these problems, first, we propose the upgraded Transformer for Panoramic Semantic Segmentation, i.e., Trans4PASS+, equipped with Deformable Patch Embedding (DPE) and Deformable MLP (DMLPv2) modules for handling object deformations and image distortions whenever (before or after adaptation) and wherever (shallow or deep levels). Second, we enhance the Mutual Prototypical Adaptation (MPA) strategy via pseudo-label rectification for unsupervised domain adaptive panoramic segmentation. Third, aside from Pinhole-to-Panoramic (Pin2Pan) adaptation, we create a new dataset (SynPASS) with 9,080 panoramic images, facilitating Synthetic-to-Real (Syn2Real) adaptation scheme in 360° imagery. Extensive experiments are conducted, which cover indoor and outdoor scenarios, and each of them is investigated with Pin2Pan and Syn2Real regimens. Trans4PASS+ achieves state-of-the-art performances on four domain adaptive panoramic semantic segmentation benchmarks. Code is available at https://github.com/jamycheung/Trans4PASS.

Jiaming Zhang, Ruiping Liu, Hao Shi et al.

Multimodal fusion can make semantic segmentation more robust. However, fusing an arbitrary number of modalities remains underexplored. To delve into this problem, we create the DeLiVER arbitrary-modal segmentation benchmark, covering Depth, LiDAR, multiple Views, Events, and RGB. Aside from this, we provide this dataset in four severe weather conditions as well as five sensor failure cases to exploit modal complementarity and resolve partial outages. To make this possible, we present the arbitrary cross-modal segmentation model CMNeXt. It encompasses a Self-Query Hub (SQ-Hub) designed to extract effective information from any modality for subsequent fusion with the RGB representation and adds only negligible amounts of parameters (~0.01M) per additional modality. On top, to efficiently and flexibly harvest discriminative cues from the auxiliary modalities, we introduce the simple Parallel Pooling Mixer (PPX). With extensive experiments on a total of six benchmarks, our CMNeXt achieves state-of-the-art performance on the DeLiVER, KITTI-360, MFNet, NYU Depth V2, UrbanLF, and MCubeS datasets, allowing to scale from 1 to 81 modalities. On the freshly collected DeLiVER, the quad-modal CMNeXt reaches up to 66.30% in mIoU with a +9.10% gain as compared to the mono-modal baseline. The DeLiVER dataset and our code are at: https://jamycheung.github.io/DELIVER.html.

Constantin Seibold, Simon Reiß, M. Saquib Sarfraz et al.

When reading images, radiologists generate text reports describing the findings therein. Current state-of-the-art computer-aided diagnosis tools utilize a fixed set of predefined categories automatically extracted from these medical reports for training. This form of supervision limits the potential usage of models as they are unable to pick up on anomalies outside of their predefined set, thus, making it a necessity to retrain the classifier with additional data when faced with novel classes. In contrast, we investigate direct text supervision to break away from this closed set assumption. By doing so, we avoid noisy label extraction via text classifiers and incorporate more contextual information. We employ a contrastive global-local dual-encoder architecture to learn concepts directly from unstructured medical reports while maintaining its ability to perform free form classification. We investigate relevant properties of open set recognition for radiological data and propose a method to employ currently weakly annotated data into training. We evaluate our approach on the large-scale chest X-Ray datasets MIMIC-CXR, CheXpert, and ChestX-Ray14 for disease classification. We show that despite using unstructured medical report supervision, we perform on par with direct label supervision through a sophisticated inference setting.

Alexander Jaus, Constantin Seibold, Simon Reiß et al.

Pathological structures in medical images are typically deviations from the expected anatomy of a patient. While clinicians consider this interplay between anatomy and pathology, recent deep learning algorithms specialize in recognizing either one of the two, rarely considering the patient's body from such a joint perspective. In this paper, we develop a generalist segmentation model that combines anatomical and pathological information, aiming to enhance the segmentation accuracy of pathological features. Our Anatomy-Pathology Exchange (APEx) training utilizes a query-based segmentation transformer which decodes a joint feature space into query-representations for human anatomy and interleaves them via a mixing strategy into the pathology-decoder for anatomy-informed pathology predictions. In doing so, we are able to report the best results across the board on FDG-PET-CT and Chest X-Ray pathology segmentation tasks with a margin of up to 3.3% as compared to strong baseline methods. Code and models will be publicly available at github.com/alexanderjaus/APEx.

Constantin Seibold, Simon Reiß, Saquib Sarfraz et al.

In clinical radiology reports, doctors capture important information about the patient's health status. They convey their observations from raw medical imaging data about the inner structures of a patient. As such, formulating reports requires medical experts to possess wide-ranging knowledge about anatomical regions with their normal, healthy appearance as well as the ability to recognize abnormalities. This explicit grasp on both the patient's anatomy and their appearance is missing in current medical image-processing systems as annotations are especially difficult to gather. This renders the models to be narrow experts e.g. for identifying specific diseases. In this work, we recover this missing link by adding human anatomy into the mix and enable the association of content in medical reports to their occurrence in associated imagery (medical phrase grounding). To exploit anatomical structures in this scenario, we present a sophisticated automatic pipeline to gather and integrate human bodily structures from computed tomography datasets, which we incorporate in our PAXRay: A Projected dataset for the segmentation of Anatomical structures in X-Ray data. Our evaluation shows that methods that take advantage of anatomical information benefit heavily in visually grounding radiologists' findings, as our anatomical segmentations allow for up to absolute 50% better grounding results on the OpenI dataset as compared to commonly used region proposals. The PAXRay dataset is available at https://constantinseibold.github.io/paxray/.

Zhifeng Teng, Jiaming Zhang, Kailun Yang et al.

Seeing only a tiny part of the whole is not knowing the full circumstance. Bird's-eye-view (BEV) perception, a process of obtaining allocentric maps from egocentric views, is restricted when using a narrow Field of View (FoV) alone. In this work, mapping from 360° panoramas to BEV semantics, the 360BEV task, is established for the first time to achieve holistic representations of indoor scenes in a top-down view. Instead of relying on narrow-FoV image sequences, a panoramic image with depth information is sufficient to generate a holistic BEV semantic map. To benchmark 360BEV, we present two indoor datasets, 360BEV-Matterport and 360BEV-Stanford, both of which include egocentric panoramic images and semantic segmentation labels, as well as allocentric semantic maps. Besides delving deep into different mapping paradigms, we propose a dedicated solution for panoramic semantic mapping, namely 360Mapper. Through extensive experiments, our methods achieve 44.32% and 45.78% in mIoU on both datasets respectively, surpassing previous counterparts with gains of +7.60% and +9.70% in mIoU. Code and datasets are available at the project page: https://jamycheung.github.io/360BEV.html.

Zdravko Marinov, Simon Reiß, David Kersting et al.

Positron Emission Tomography (PET) and Computer Tomography (CT) are routinely used together to detect tumors. PET/CT segmentation models can automate tumor delineation, however, current multimodal models do not fully exploit the complementary information in each modality, as they either concatenate PET and CT data or fuse them at the decision level. To combat this, we propose Mirror U-Net, which replaces traditional fusion methods with multimodal fission by factorizing the multimodal representation into modality-specific branches and an auxiliary multimodal decoder. At these branches, Mirror U-Net assigns a task tailored to each modality to reinforce unimodal features while preserving multimodal features in the shared representation. In contrast to previous methods that use either fission or multi-task learning, Mirror U-Net combines both paradigms in a unified framework. We explore various task combinations and examine which parameters to share in the model. We evaluate Mirror U-Net on the AutoPET PET/CT and on the multimodal MSD BrainTumor datasets, demonstrating its effectiveness in multimodal segmentation and achieving state-of-the-art performance on both datasets. Our code will be made publicly available.

Constantin Seibold, Alexander Jaus, Matthias A. Fink et al.

Purpose: Interpreting chest radiographs (CXR) remains challenging due to the ambiguity of overlapping structures such as the lungs, heart, and bones. To address this issue, we propose a novel method for extracting fine-grained anatomical structures in CXR using pseudo-labeling of three-dimensional computed tomography (CT) scans. Methods: We created a large-scale dataset of 10,021 thoracic CTs with 157 labels and applied an ensemble of 3D anatomy segmentation models to extract anatomical pseudo-labels. These labels were projected onto a two-dimensional plane, similar to the CXR, allowing the training of detailed semantic segmentation models for CXR without any manual annotation effort. Results: Our resulting segmentation models demonstrated remarkable performance on CXR, with a high average model-annotator agreement between two radiologists with mIoU scores of 0.93 and 0.85 for frontal and lateral anatomy, while inter-annotator agreement remained at 0.95 and 0.83 mIoU. Our anatomical segmentations allowed for the accurate extraction of relevant explainable medical features such as the cardio-thoracic-ratio. Conclusion: Our method of volumetric pseudo-labeling paired with CT projection offers a promising approach for detailed anatomical segmentation of CXR with a high agreement with human annotators. This technique may have important clinical implications, particularly in the analysis of various thoracic pathologies.

Alexander Jaus, Simon Reiß, Jens Kleesiek et al.

In this work, we describe our approach to compete in the autoPET3 datacentric track. While conventional wisdom suggests that larger datasets lead to better model performance, recent studies indicate that excluding certain training samples can enhance model accuracy. We find that in the autoPETIII dataset, a model that is trained on the entire dataset exhibits undesirable characteristics by producing a large number of false positives particularly for PSMA-PETs. We counteract this by removing the easiest samples from the training dataset as measured by the model loss before retraining from scratch. Using the proposed approach we manage to drive down the false negative volume and improve upon the baseline model in both false negative volume and dice score on the preliminary test set. Code and pre-trained models are available at github.com/alexanderjaus/autopet3_datadiet.

Alessio Negrini, Simon Reiß

Recent advancements in medical image analysis have led to the development of highly specialized models tailored to specific clinical tasks. These models have demonstrated exceptional performance and remain a crucial research direction. Yet, their applicability is limited to predefined tasks, requiring expertise and extensive resources for development and adaptation. In contrast, generalist models offer a different form of utility: allowing medical practitioners to define tasks on the fly without the need for task-specific model development. In this work, we explore how to train generalist models for the domain of retinal optical coherence tomography using visual in-context learning (VICL), i.e., training models to generalize across tasks based on a few examples provided at inference time. To facilitate rigorous assessment, we propose a broad evaluation protocol tailored to VICL in OCT. We extensively evaluate a state-of-the-art medical VICL approach on multiple retinal OCT datasets, establishing a first baseline to highlight the potential and current limitations of in-context learning for OCT. To foster further research and practical adoption, we openly release our code.

Omar Moured, Yufan Chen, Ruiping Liu et al.

Charts play a critical role in data analysis and visualization, yet real-world applications often present charts with challenging or noisy features. However, "outlier charts" pose a substantial challenge even for Multimodal Large Language Models (MLLMs), which can struggle to interpret perturbed charts. In this work, we introduce CHAOS (CHart Analysis with Outlier Samples), a robustness benchmark to systematically evaluate MLLMs against chart perturbations. CHAOS encompasses five types of textual and ten types of visual perturbations, each presented at three levels of severity (easy, mid, hard) inspired by the study result of human evaluation. The benchmark includes 13 state-of-the-art MLLMs divided into three groups (i.e., general-, document-, and chart-specific models) according to the training scope and data. Comprehensive analysis involves two downstream tasks (ChartQA and Chart-to-Text). Extensive experiments and case studies highlight critical insights into robustness of models across chart perturbations, aiming to guide future research in chart understanding domain. Data and code are publicly available at: http://huggingface.co/datasets/omoured/CHAOS.

Alina Roitberg, David Schneider, Aulia Djamal et al.

Recognizing Activities of Daily Living (ADL) is a vital process for intelligent assistive robots, but collecting large annotated datasets requires time-consuming temporal labeling and raises privacy concerns, e.g., if the data is collected in a real household. In this work, we explore the concept of constructing training examples for ADL recognition by playing life simulation video games and introduce the SIMS4ACTION dataset created with the popular commercial game THE SIMS 4. We build Sims4Action by specifically executing actions-of-interest in a "top-down" manner, while the gaming circumstances allow us to freely switch between environments, camera angles and subject appearances. While ADL recognition on gaming data is interesting from the theoretical perspective, the key challenge arises from transferring it to the real-world applications, such as smart-homes or assistive robotics. To meet this requirement, Sims4Action is accompanied with a GamingToReal benchmark, where the models are evaluated on real videos derived from an existing ADL dataset. We integrate two modern algorithms for video-based activity recognition in our framework, revealing the value of life simulation video games as an inexpensive and far less intrusive source of training data. However, our results also indicate that tasks involving a mixture of gaming and real data are challenging, opening a new research direction. We will make our dataset publicly available at https://github.com/aroitberg/sims4action.

Alexander Jaus, Constantin Seibold, Simon Reiß et al.

We present Connected-Component~(CC)-Metrics, a novel semantic segmentation evaluation protocol, targeted to align existing semantic segmentation metrics to a multi-instance detection scenario in which each connected component matters. We motivate this setup in the common medical scenario of semantic metastases segmentation in a full-body PET/CT. We show how existing semantic segmentation metrics suffer from a bias towards larger connected components contradicting the clinical assessment of scans in which tumor size and clinical relevance are uncorrelated. To rebalance existing segmentation metrics, we propose to evaluate them on a per-component basis thus giving each tumor the same weight irrespective of its size. To match predictions to ground-truth segments, we employ a proximity-based matching criterion, evaluating common metrics locally at the component of interest. Using this approach, we break free of biases introduced by large metastasis for overlap-based metrics such as Dice or Surface Dice. CC-Metrics also improves distance-based metrics such as Hausdorff Distances which are uninformative for small changes that do not influence the maximum or 95th percentile, and avoids pitfalls introduced by directly combining counting-based metrics with overlap-based metrics as it is done in Panoptic Quality.

David Schneider, Simon Reiß, Marco Kugler et al.

Exploring the intricate dynamics between muscular and skeletal structures is pivotal for understanding human motion. This domain presents substantial challenges, primarily attributed to the intensive resources required for acquiring ground truth muscle activation data, resulting in a scarcity of datasets. In this work, we address this issue by establishing Muscles in Time (MinT), a large-scale synthetic muscle activation dataset. For the creation of MinT, we enriched existing motion capture datasets by incorporating muscle activation simulations derived from biomechanical human body models using the OpenSim platform, a common approach in biomechanics and human motion research. Starting from simple pose sequences, our pipeline enables us to extract detailed information about the timing of muscle activations within the human musculoskeletal system. Muscles in Time contains over nine hours of simulation data covering 227 subjects and 402 simulated muscle strands. We demonstrate the utility of this dataset by presenting results on neural network-based muscle activation estimation from human pose sequences with two different sequence-to-sequence architectures. Data and code are provided under https://simplexsigil.github.io/mint.

Cedric Zöllner, Simon Reiß, Alexander Jaus et al.

When preoperative planning for surgeries is conducted on the basis of medical images, artificial intelligence methods can support medical doctors during assessment. In this work, we consider medical guidelines for preoperative planning of the transcatheter aortic valve replacement (TAVR) and identify tasks, that may be supported via semantic segmentation models by making relevant anatomical structures measurable in computed tomography scans. We first derive fine-grained TAVR-relevant pseudo-labels from coarse-grained anatomical information, in order to train segmentation models and quantify how well they are able to find these structures in the scans. Furthermore, we propose an adaptation to the loss function in training these segmentation models and through this achieve a +1.27% Dice increase in performance. Our fine-grained TAVR-relevant pseudo-labels and the computed tomography scans we build upon are available at https://doi.org/10.5281/zenodo.16274176.

Simon Reiß, Zdravko Marinov, Alexander Jaus et al.

In this paper, we explore the potential of visual in-context learning to enable a single model to handle multiple tasks and adapt to new tasks during test time without re-training. Unlike previous approaches, our focus is on training in-context learners to adapt to sequences of tasks, rather than individual tasks. Our goal is to solve complex tasks that involve multiple intermediate steps using a single model, allowing users to define entire vision pipelines flexibly at test time. To achieve this, we first examine the properties and limitations of visual in-context learning architectures, with a particular focus on the role of codebooks. We then introduce a novel method for training in-context learners using a synthetic compositional task generation engine. This engine bootstraps task sequences from arbitrary segmentation datasets, enabling the training of visual in-context learners for compositional tasks. Additionally, we investigate different masking-based training objectives to gather insights into how to train models better for solving complex, compositional tasks. Our exploration not only provides important insights especially for multi-modal medical task sequences but also highlights challenges that need to be addressed.

Alexander Jaus, Zdravko Marinov, Constantin Seibold et al.

Improving label quality in medical image segmentation is costly, but its benefits remain unclear. We systematically evaluate its impact using multiple pseudo-labeled versions of CT datasets, generated by models like nnU-Net, TotalSegmentator, and MedSAM. Our results show that while higher-quality labels improve in-domain performance, gains remain unclear if below a small threshold. For pre-training, label quality has minimal impact, suggesting that models rather transfer general concepts than detailed annotations. These findings provide guidance on when improving label quality is worth the effort.

Constantin Seibold, Hamza Kalisch, Lukas Heine et al.

In this paper, we tackle the challenge of instance segmentation for foreign objects in chest radiographs, commonly seen in postoperative follow-ups with stents, pacemakers, or ingested objects in children. The diversity of foreign objects complicates dense annotation, as shown in insufficient existing datasets. To address this, we propose the simple generation of synthetic data through (1) insertion of arbitrary shapes (lines, polygons, ellipses) with varying contrasts and opacities, and (2) cut-paste augmentations from a small set of semi-automatically extracted labels. These insertions are guided by anatomy labels to ensure realistic placements, such as stents appearing only in relevant vessels. Our approach enables networks to segment complex structures with minimal manually labeled data. Notably, it achieves performance comparable to fully supervised models while using 93\% fewer manual annotations.

Tu Anh Dinh, Carlos Mullov, Leonard Bärmann et al.

With the rapid development of Large Language Models (LLMs), it is crucial to have benchmarks which can evaluate the ability of LLMs on different domains. One common use of LLMs is performing tasks on scientific topics, such as writing algorithms, querying databases or giving mathematical proofs. Inspired by the way university students are evaluated on such tasks, in this paper, we propose SciEx - a benchmark consisting of university computer science exam questions, to evaluate LLMs ability on solving scientific tasks. SciEx is (1) multilingual, containing both English and German exams, and (2) multi-modal, containing questions that involve images, and (3) contains various types of freeform questions with different difficulty levels, due to the nature of university exams. We evaluate the performance of various state-of-the-art LLMs on our new benchmark. Since SciEx questions are freeform, it is not straightforward to evaluate LLM performance. Therefore, we provide human expert grading of the LLM outputs on SciEx. We show that the free-form exams in SciEx remain challenging for the current LLMs, where the best LLM only achieves 59.4\% exam grade on average. We also provide detailed comparisons between LLM performance and student performance on SciEx. To enable future evaluation of new LLMs, we propose using LLM-as-a-judge to grade the LLM answers on SciEx. Our experiments show that, although they do not perform perfectly on solving the exams, LLMs are decent as graders, achieving 0.948 Pearson correlation with expert grading.

Constantin Seibold, Simon Reiß, Jens Kleesiek et al.

Producing densely annotated data is a difficult and tedious task for medical imaging applications. To address this problem, we propose a novel approach to generate supervision for semi-supervised semantic segmentation. We argue that visually similar regions between labeled and unlabeled images likely contain the same semantics and therefore should share their label. Following this thought, we use a small number of labeled images as reference material and match pixels in an unlabeled image to the semantics of the best fitting pixel in a reference set. This way, we avoid pitfalls such as confirmation bias, common in purely prediction-based pseudo-labeling. Since our method does not require any architectural changes or accompanying networks, one can easily insert it into existing frameworks. We achieve the same performance as a standard fully supervised model on X-ray anatomy segmentation, albeit 95% fewer labeled images. Aside from an in-depth analysis of different aspects of our proposed method, we further demonstrate the effectiveness of our reference-guided learning paradigm by comparing our approach against existing methods for retinal fluid segmentation with competitive performance as we improve upon recent work by up to 15% mean IoU.

Simon Reiß, Constantin Seibold, Alexander Freytag et al.

Pixel-wise segmentation is one of the most data and annotation hungry tasks in our field. Providing representative and accurate annotations is often mission-critical especially for challenging medical applications. In this paper, we propose a semi-weakly supervised segmentation algorithm to overcome this barrier. Our approach is based on a new formulation of deep supervision and student-teacher model and allows for easy integration of different supervision signals. In contrast to previous work, we show that care has to be taken how deep supervision is integrated in lower layers and we present multi-label deep supervision as the most important secret ingredient for success. With our novel training regime for segmentation that flexibly makes use of images that are either fully labeled, marked with bounding boxes, just global labels, or not at all, we are able to cut the requirement for expensive labels by 94.22% - narrowing the gap to the best fully supervised baseline to only 5% mean IoU. Our approach is validated by extensive experiments on retinal fluid segmentation and we provide an in-depth analysis of the anticipated effect each annotation type can have in boosting segmentation performance.

Kailun Yang, Jiaming Zhang, Simon Reiß et al.

Convolutional Networks (ConvNets) excel at semantic segmentation and have become a vital component for perception in autonomous driving. Enabling an all-encompassing view of street-scenes, omnidirectional cameras present themselves as a perfect fit in such systems. Most segmentation models for parsing urban environments operate on common, narrow Field of View (FoV) images. Transferring these models from the domain they were designed for to 360-degree perception, their performance drops dramatically, e.g., by an absolute 30.0% (mIoU) on established test-beds. To bridge the gap in terms of FoV and structural distribution between the imaging domains, we introduce Efficient Concurrent Attention Networks (ECANets), directly capturing the inherent long-range dependencies in omnidirectional imagery. In addition to the learned attention-based contextual priors that can stretch across 360-degree images, we upgrade model training by leveraging multi-source and omni-supervised learning, taking advantage of both: Densely labeled and unlabeled data originating from multiple datasets. To foster progress in panoramic image segmentation, we put forward and extensively evaluate models on Wild PAnoramic Semantic Segmentation (WildPASS), a dataset designed to capture diverse scenes from all around the globe. Our novel model, training regimen and multi-source prediction fusion elevate the performance (mIoU) to new state-of-the-art results on the public PASS (60.2%) and the fresh WildPASS (69.0%) benchmarks.