Alejandro Hernández Cano

Zeming Chen, Alejandro Hernández Cano, Angelika Romanou et al. · allen-ai

Large language models (LLMs) can potentially democratize access to medical knowledge. While many efforts have been made to harness and improve LLMs' medical knowledge and reasoning capacities, the resulting models are either closed-source (e.g., PaLM, GPT-4) or limited in scale (<= 13B parameters), which restricts their abilities. In this work, we improve access to large-scale medical LLMs by releasing MEDITRON: a suite of open-source LLMs with 7B and 70B parameters adapted to the medical domain. MEDITRON builds on Llama-2 (through our adaptation of Nvidia's Megatron-LM distributed trainer), and extends pretraining on a comprehensively curated medical corpus, including selected PubMed articles, abstracts, and internationally-recognized medical guidelines. Evaluations using four major medical benchmarks show significant performance gains over several state-of-the-art baselines before and after task-specific finetuning. Overall, MEDITRON achieves a 6% absolute performance gain over the best public baseline in its parameter class and 3% over the strongest baseline we finetuned from Llama-2. Compared to closed-source LLMs, MEDITRON-70B outperforms GPT-3.5 and Med-PaLM and is within 5% of GPT-4 and 10% of Med-PaLM-2. We release our code for curating the medical pretraining corpus and the MEDITRON model weights to drive open-source development of more capable medical LLMs.

Jonathan Coles, Stefano Schuppli, Lukas Drescher et al.

Large Language Models (LLMs) have surged as a transformative technology for science and society, prompting governments worldwide to pursue sovereign AI capabilities that ensure data compliance and cultural representation. However, the associated capital costs and engineering complexity required to train these models have largely restricted such capabilities to the private sector, leaving a significant gap for public institutions. This paper details the engineering journey behind training Apertus, a fully open multilingual foundation model, on the Alps supercomputer. Representing a first-of-its-kind achievement for academia at the 70B parameter scale, we successfully deployed a massive pre-training campaign on one of Europe's largest systems for open science, powered by NVIDIA GH200 Grace Hopper Superchips. We detail the challenges encountered in readying HPC infrastructure for training AI models, from overcoming storage bottlenecks to stabilizing large-scale interconnects, and the lessons learned in transforming a supercomputer into a resilient software-defined Machine Learning Platform. Finally, we discuss the post-training requirements and evolution of our Machine Learning platform, outlining how this initial release lays the groundwork for a sustained, iterative operational capability, in particular for fine tuning foundation models, that extends well beyond a single model training run.