Saikit Lam

h-index19
2papers
1,363citations

2 Papers

1.2QMFeb 12, 2025
Multi-Omics Fusion with Soft Labeling for Enhanced Prediction of Distant Metastasis in Nasopharyngeal Carcinoma Patients after Radiotherapy

Jiabao Sheng, SaiKit Lam, Jiang Zhang et al.

Omics fusion has emerged as a crucial preprocessing approach in the field of medical image processing, providing significant assistance to several studies. One of the challenges encountered in the integration of omics data is the presence of unpredictability arising from disparities in data sources and medical imaging equipment. In order to overcome this challenge and facilitate the integration of their joint application to specific medical objectives, this study aims to develop a fusion methodology that mitigates the disparities inherent in omics data. The utilization of the multi-kernel late-fusion method has gained significant popularity as an effective strategy for addressing this particular challenge. An efficient representation of the data may be achieved by utilizing a suitable single-kernel function to map the inherent features and afterward merging them in a space with a high number of dimensions. This approach effectively addresses the differences noted before. The inflexibility of label fitting poses a constraint on the use of multi-kernel late-fusion methods in complex nasopharyngeal carcinoma (NPC) datasets, hence affecting the efficacy of general classifiers in dealing with high-dimensional characteristics. This innovative methodology aims to increase the disparity between the two cohorts, hence providing a more flexible structure for the allocation of labels. The examination of the NPC-ContraParotid dataset demonstrates the model's robustness and efficacy, indicating its potential as a valuable tool for predicting distant metastases in patients with nasopharyngeal carcinoma (NPC).

8.6IVFeb 5, 2025
Proxy Prompt: Endowing SAM and SAM 2 with Auto-Interactive-Prompt for Medical Segmentation

Wang Xinyi, Kang Hongyu, Wei Peishan et al.

In this paper, we aim to address the unmet demand for automated prompting and enhanced human-model interactions of SAM and SAM2 for the sake of promoting their widespread clinical adoption. Specifically, we propose Proxy Prompt (PP), auto-generated by leveraging non-target data with a pre-annotated mask. We devise a novel 3-step context-selection strategy for adaptively selecting the most representative contextual information from non-target data via vision mamba and selective maps, empowering the guiding capability of non-target image-mask pairs for segmentation on target image/video data. To reinforce human-model interactions in PP, we further propose a contextual colorization module via a dual-reverse cross-attention to enhance interactions between target features and contextual-embedding with amplifying distinctive features of user-defined object(s). Via extensive evaluations, our method achieves state-of-the-art performance on four public datasets and yields comparable results with fully-trained models, even when trained with only 16 image masks.