Zifan He

Zongyue Qin, Ziniu Hu, Zifan He et al.

Large language models (LLMs) have achieved remarkable success across diverse tasks, yet their inference processes are hindered by substantial time and energy demands due to single-token generation at each decoding step. While previous methods such as speculative decoding mitigate these inefficiencies by producing multiple tokens per step, each token is still generated by its single-token distribution, thereby enhancing speed without improving effectiveness. In contrast, our work simultaneously enhances inference speed and improves the output effectiveness. We consider multi-token joint decoding (MTJD), which generates multiple tokens from their joint distribution at each iteration, theoretically reducing perplexity and enhancing task performance. However, MTJD suffers from the high cost of sampling from the joint distribution of multiple tokens. Inspired by speculative decoding, we introduce multi-token assisted decoding (MTAD), a novel framework designed to accelerate MTJD. MTAD leverages a smaller auxiliary model to approximate the joint distribution of a larger model, incorporating a verification mechanism that not only ensures the accuracy of this approximation, but also improves the decoding efficiency over conventional speculative decoding. Theoretically, we demonstrate that MTAD closely approximates exact MTJD with bounded error. Empirical evaluations using Llama-2 and OPT models ranging from 13B to 70B parameters across various tasks reveal that MTAD reduces perplexity by 21.2% and improves downstream performance compared to standard single-token sampling. Furthermore, MTAD achieves a 1.42x speed-up and consumes 1.54x less energy than conventional speculative decoding methods. These results highlight MTAD's ability to make multi-token joint decoding both effective and efficient, promoting more sustainable and high-performance deployment of LLMs.

Maryam Haghifam, Zifan He, Jason Cong et al.

Transformer-based LLMs achieve strong results on many language tasks; however, long inputs remain challenging because context windows are finite, and prefill latency and memory grow rapidly with prompt length. Flat token-stream processing and chunk-based retrieval can therefore spend substantial computation and context budget on text unrelated to the query. Offline-indexed RAG additionally introduces external storage and index management overhead, and typically appends retrieved evidence as raw text, increasing prefill cost and latency. H^{2}MT makes long-context inference structure-aware: it builds a semantic hierarchy offline, computes a memory embedding for each node via bottom-up post-order aggregation, and routes queries coarse-to-fine at inference to prune irrelevant branches early. On LongBench QA (NarrativeQA, HotpotQA, QASPER) and two structured technical-document settings, H MT achieves favorable quality efficiency trade-offs, delivering competitive ROUGE-L and F1 (where applicable) with lower peak GPU memory and time-to-first-token (TTFT) than prompt compression, memory-token methods, and retrieval-augmented generation baselines.

Zongyue Qin, Zifan He, Neha Prakriya et al.

Large language models (LLMs) have shown outstanding performance across numerous real-world tasks. However, the autoregressive nature of these models makes the inference process slow and costly. Speculative decoding has emerged as a promising solution, leveraging a smaller auxiliary model to draft future tokens, which are then validated simultaneously by the larger model, achieving a speed-up of 1-2x. Although speculative decoding matches the same distribution as multinomial sampling, multinomial sampling itself is prone to suboptimal outputs, whereas beam sampling is widely recognized for producing higher-quality results by maintaining multiple candidate sequences at each step. This paper explores the novel integration of speculative decoding with beam sampling. However, there are four key challenges: (1) how to generate multiple sequences from the larger model's distribution given drafts sequences from the small model; (2) how to dynamically optimize the number of beams to balance efficiency and accuracy; (3) how to efficiently verify the multiple drafts in parallel; and (4) how to address the extra memory costs inherent in beam sampling. To address these challenges, we propose dynamic-width speculative beam decoding (DSBD). Specifically, we first introduce a novel draft and verification scheme that generates multiple sequences following the large model's distribution based on beam sampling trajectories from the small model. Then, we introduce an adaptive mechanism to dynamically tune the number of beams based on the context, optimizing efficiency and effectiveness. Besides, we extend tree-based parallel verification to handle multiple trees simultaneously, accelerating the verification process. Finally, we illustrate a simple modification to our algorithm to mitigate the memory overhead of beam sampling...

Zifan He, Rui Ma, Yizhou Sun et al.

Modern large language models (LLMs) increasingly depends on efficient long-context processing and generation mechanisms, including sparse attention, retrieval-augmented generation (RAG), and compressed contextual memory, to support complex reasoning. We show that these optimizations can be unified into a four-step memory processing pipeline: Prepare Memory, Compute Relevancy, Retrieval, and Apply to Inference. Through systematic profiling, we identify a 22%-97% memory processing overhead in LLM inference and strong heterogeneity in its computational characteristics. Motivated by this insight, we argue that \textbf{heterogeneous systems} are well-suited to accelerate memory processing and thus end-to-end inference. We demonstrate this approach on a GPU-FPGA system by offloading sparse, irregular, and memory-bounded operations to FPGAs while retaining compute-intensive operations on GPUs. Evaluated on an AMD MI210 GPU and an Alveo U55C FPGA, our system is $1.04\sim2.2\times$ faster and requires $1.11\sim4.7\times$ less energy across multiple LLM inference optimizations than the GPU baseline (similar results hold on NVIDIA A100). These results establish heterogeneous systems as a practical direction for efficient LLM memory processing and inform future heterogeneous hardware design.

Jiahao Zhang, Zifan He, Nicholas Fraser et al.

We present FlexLLM, a composable High-Level Synthesis (HLS) library for rapid development of domain-specific LLM accelerators. FlexLLM exposes key architectural degrees of freedom for stage-customized inference, enabling hybrid designs that tailor temporal reuse and spatial dataflow differently for prefill and decode, and provides a comprehensive quantization suite to support accurate low-bit deployment. Using FlexLLM, we build a complete inference system for the Llama-3.2 1B model in under two months with only 1K lines of code. The system includes: (1) a stage-customized accelerator with hardware-efficient quantization (12.68 WikiText-2 PPL) surpassing SpinQuant baseline, and (2) a Hierarchical Memory Transformer (HMT) plug-in for efficient long-context processing. On the AMD U280 FPGA at 16nm, the accelerator achieves 1.29$\times$ end-to-end speedup, 1.64$\times$ higher decode throughput, and 3.14$\times$ better energy efficiency than an NVIDIA A100 GPU (7nm) running BF16 inference; projected results on the V80 FPGA at 7nm reach 4.71$\times$, 6.55$\times$, and 4.13$\times$, respectively. In long-context scenarios, integrating the HMT plug-in reduces prefill latency by 23.23$\times$ and extends the context window by 64$\times$, delivering 1.10$\times$/4.86$\times$ lower end-to-end latency and 5.21$\times$/6.27$\times$ higher energy efficiency on the U280/V80 compared to the A100 baseline. FlexLLM thus bridges algorithmic innovation in LLM inference and high-performance accelerators with minimal manual effort.

Zifan He, Anderson Truong, Yingqi Cao et al.

The rise of deep neural networks (DNNs) has driven an increased demand for computing power and memory. Modern DNNs exhibit high data volume variation (HDV) across tasks, which poses challenges for FPGA acceleration: conventional accelerators rely on fixed execution patterns (dataflow or sequential) that can lead to pipeline stalls or necessitate frequent off-chip memory accesses. To address these challenges, we introduce the Inter-Task Auto-Reconfigurable Accelerator (InTAR), a novel accelerator design methodology for HDV applications on FPGAs. InTAR combines the high computational efficiency of sequential execution with the reduced off-chip memory overhead of dataflow execution. It switches execution patterns automatically with a static schedule determined before circuit design based on resource constraints and problem sizes. Unlike previous reconfigurable accelerators, InTAR encodes reconfiguration schedules during circuit design, allowing model-specific optimizations that allocate only the necessary logic and interconnects. Thus, InTAR achieves a high clock frequency with fewer resources and low reconfiguration time. Furthermore, InTAR supports high-level tools such as HLS for fast design generation. We implement a set of multi-task HDV DNN kernels using InTAR. Compared with dataflow and sequential accelerators, InTAR exhibits $\mathbf{1.8\times}$ and $\mathbf{7.1 \times}$ speedups correspondingly. Moreover, we extend InTAR to GPT-2 medium as a more complex example, which is $\mathbf{3.65 \sim 39.14\times}$ faster and a $\mathbf{1.72 \sim 10.44\times}$ more DSP efficient than SoTA accelerators (Allo and DFX) on FPGAs. Additionally, this design demonstrates $\mathbf{1.66 \sim 7.17\times}$ better power efficiency than GPUs. Code: https://github.com/OswaldHe/InTAR

Zifan He, Yingqi Cao, Zongyue Qin et al.

Transformer-based large language models (LLM) have been widely used in language processing applications. However, due to the memory constraints of the devices, most of them restrict the context window. Even though recurrent models in previous works can memorize past tokens to enable unlimited context and maintain effectiveness, they have ``flat'' memory architectures. Such architectures have limitations in selecting and filtering information. Since humans are good at learning and self-adjustment, we believe that imitating brain memory hierarchy is beneficial for model memorization. Thus, we propose the Hierarchical Memory Transformer (HMT), a novel framework that facilitates a model's long-context processing ability by imitating human memorization behavior. Leveraging memory-augmented segment-level recurrence, we organize the memory hierarchy by preserving tokens from early input segments, passing memory embeddings along the sequence, and recalling relevant information from history. Evaluating general language modeling, question-answering tasks, and the summarization task, we show that HMT consistently improves the long-context processing ability of existing models. Furthermore, HMT achieves a comparable or superior generation quality to long-context LLMs with $2 \sim 57\times$ fewer parameters and $2.5 \sim 116\times$ less inference memory, significantly outperforming previous memory-augmented models. Code on Github: https://github.com/OswaldHe/HMT-pytorch.

Zifan He, Shengyu Ye, Rui Ma et al.

The rapid progress of large language models (LLMs) has advanced numerous applications, yet efficient single-batch inference remains vital for on-device intelligence. While FPGAs offer fine-grained data control and high energy efficiency, recent GPU optimizations have narrowed their advantage, especially under arithmetic-based computation. To overcome this, we leverage FPGAs' abundant on-chip memory to shift LLM inference from arithmetic- to memory-based computation through table lookups. We present LUT-LLM, the first FPGA accelerator enabling 1B+ LLM inference via vector-quantized memory operations. Our analysis identifies activation-weight co-quantization as the most effective scheme, supported by (1) bandwidth-aware parallel centroid search, (2) efficient 2D table lookups, and (3) a spatial-temporal hybrid design minimizing data caching. Implemented on an AMD V80 FPGA for a customized Qwen 3 1.7B model, LUT-LLM achieves 1.66x lower latency than AMD MI210 and 1.72x higher energy efficiency than NVIDIA A100, scaling to 32B models with 2.16x efficiency gain over A100.

Teng Wang, Zhangyi Jiang, Zhenqi He et al.

Recent studies show that Large Language Models (LLMs) achieve strong reasoning capabilities through supervised fine-tuning or reinforcement learning. However, a key approach, the Process Reward Model (PRM), suffers from reward hacking, making it unreliable in identifying the best intermediate step. In addition, the cost of annotating reasoning processes for reward modeling is high, making large-scale collection of high-quality data challenging. To address this, we propose a novel reward model approach called the Hierarchical Reward Model (HRM), which evaluates both individual and consecutive reasoning steps at both fine-grained and coarse-grained levels. HRM excels at assessing multi-step reasoning coherence, especially when flawed steps are later corrected through self-reflection. To further reduce the cost of generating training data, we introduce a lightweight and effective data augmentation strategy called Hierarchical Node Compression (HNC), which merges two consecutive reasoning steps into one within the tree structure. By applying HNC to MCTS-generated reasoning trajectories, we enhance the diversity and robustness of HRM training data while introducing controlled noise with minimal computational overhead. Empirical results on the PRM800K dataset show that HRM, together with HNC, provides more stable and reliable evaluations than PRM. Furthermore, cross-domain evaluations on the MATH500 and GSM8K datasets demonstrate HRM's strong generalization and robustness across a variety of reasoning tasks.

Fuxiang Huang, Jiayi Zhu, Yunfang Yu et al.

Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer-related mortality in women globally. Mammography is essential for the early detection and diagnosis of breast lesions. Despite recent progress in foundation models (FMs) for mammogram analysis, their clinical translation remains constrained by several fundamental limitations, including insufficient diversity in training data, limited model generalizability, and a lack of comprehensive evaluation across clinically relevant tasks. Here, we introduce VersaMammo, a versatile foundation model for mammograms, designed to overcome these limitations. We curated the largest multi-institutional mammogram dataset to date, comprising 706,239 images from 21 sources. To improve generalization, we propose a two-stage pre-training strategy to develop VersaMammo, a mammogram foundation model. First, a teacher model is trained via self-supervised learning to extract transferable features from unlabeled mammograms. Then, supervised learning combined with knowledge distillation transfers both features and clinical knowledge into VersaMammo. To ensure a comprehensive evaluation, we established a benchmark comprising 92 specific tasks, including 68 internal tasks and 24 external validation tasks, spanning 5 major clinical task categories: lesion detection, segmentation, classification, image retrieval, and visual question answering. VersaMammo achieves state-of-the-art performance, ranking first in 50 out of 68 specific internal tasks and 20 out of 24 external validation tasks, with average ranks of 1.5 and 1.2, respectively. These results demonstrate its superior generalization and clinical utility, offering a substantial advancement toward reliable and scalable breast cancer screening and diagnosis.

Cheng Jin, Fengtao Zhou, Yunfang Yu et al.

Precision oncology requires accurate molecular insights, yet obtaining these directly from genomics is costly and time-consuming for broad clinical use. Predicting complex molecular features and patient prognosis directly from routine whole-slide images (WSI) remains a major challenge for current deep learning methods. Here we introduce PathLUPI, which uses transcriptomic privileged information during training to extract genome-anchored histological embeddings, enabling effective molecular prediction using only WSIs at inference. Through extensive evaluation across 49 molecular oncology tasks using 11,257 cases among 20 cohorts, PathLUPI demonstrated superior performance compared to conventional methods trained solely on WSIs. Crucially, it achieves AUC $\geq$ 0.80 in 14 of the biomarker prediction and molecular subtyping tasks and C-index $\geq$ 0.70 in survival cohorts of 5 major cancer types. Moreover, PathLUPI embeddings reveal distinct cellular morphological signatures associated with specific genotypes and related biological pathways within WSIs. By effectively encoding molecular context to refine WSI representations, PathLUPI overcomes a key limitation of existing models and offers a novel strategy to bridge molecular insights with routine pathology workflows for wider clinical application.