Colin Zhang

Junfeng Tian, Da Zheng, Yang Cheng et al.

Large language models (LLM) have prioritized expanding the context window from which models can incorporate more information. However, training models to handle long contexts presents significant challenges. These include the scarcity of high-quality natural long-context data, the potential for performance degradation on short-context tasks, and the reduced training efficiency associated with attention mechanisms. In this paper, we introduce Untie the Knots (\textbf{UtK}), a novel data augmentation strategy employed during the continue pre-training phase, designed to efficiently enable LLMs to gain long-context capabilities without the need to modify the existing data mixture. In particular, we chunk the documents, shuffle the chunks, and create a complex and knotted structure of long texts; LLMs are then trained to untie these knots and identify relevant segments within seemingly chaotic token sequences. This approach greatly improves the model's performance by accurately attending to relevant information in long context and the training efficiency is also largely increased. We conduct extensive experiments on models with 7B and 72B parameters, trained on 20 billion tokens, demonstrating that UtK achieves 75\% and 84.5\% accurracy on RULER at 128K context length, significantly outperforming other long context strategies. The trained models will open-source for further research.

Weijian Luo, Colin Zhang, Debing Zhang et al.

We propose Diff-Instruct* (DI*), a data-efficient post-training approach for one-step text-to-image generative models to improve its human preferences without requiring image data. Our method frames alignment as online reinforcement learning from human feedback (RLHF), which optimizes the one-step model to maximize human reward functions while being regularized to be kept close to a reference diffusion process. Unlike traditional RLHF approaches, which rely on the Kullback-Leibler divergence as the regularization, we introduce a novel general score-based divergence regularization that substantially improves performance as well as post-training stability. Although the general score-based RLHF objective is intractable to optimize, we derive a strictly equivalent tractable loss function in theory that can efficiently compute its \emph{gradient} for optimizations. We introduce \emph{DI*-SDXL-1step}, which is a 2.6B one-step text-to-image model at a resolution of $1024\times 1024$, post-trained from DMD2 w.r.t SDXL. \textbf{Our 2.6B \emph{DI*-SDXL-1step} model outperforms the 50-step 12B FLUX-dev model} in ImageReward, PickScore, and CLIP score on the Parti prompts benchmark while using only 1.88\% of the inference time. This result clearly shows that with proper post-training, the small one-step model is capable of beating huge multi-step diffusion models. Our model is open-sourced at this link: https://github.com/pkulwj1994/diff_instruct_star. We hope our findings can contribute to human-centric machine learning techniques.

Colin Zhang, Yang Ha

Multiple sclerosis (MS) is a debilitating neurological disease affecting nearly one million people in the United States. Sphingosine-1-phosphate receptor 1, or S1PR1, is a protein target for MS. Siponimod, a ligand of S1PR1, was approved by the FDA in 2019 for MS treatment, but there is a demonstrated need for better therapies. To this end, we finetuned an autoencoder machine learning model that converts chemical formulas into mathematical vectors and generated over 500 molecular variants based on siponimod, out of which 25 compounds had higher predicted binding affinity to S1PR1. The model was able to generate these ligands in just under one hour. Filtering these compounds led to the discovery of six promising candidates with good drug-like properties and ease of synthesis. Furthermore, by analyzing the binding interactions for these ligands, we uncovered several chemical properties that contribute to high binding affinity to S1PR1. This study demonstrates that machine learning can accelerate the drug discovery process and reveal new insights into protein-drug interactions.

Bowen Zheng, Weijian Luo, Guang Yang et al.

Most discrete visual tokenizers rely on a default design: every position in the sequence shares the same codebook. Researchers try to scale the codebook size $K$ to get better reconstruction performance. Such a constant-codebook design hits a fundamental information-theoretic limit. We observe that the per-position conditional entropy of the training set decays so quickly along the sequence that, after a few positions, the conditional distribution becomes essentially deterministic. On ImageNet with $K=16384$, this happens within only 2 out of 256 positions, turning the remaining 254 into a memorization problem. We call this phenomenon the Entropy Cliff and formalize it with a simple expression: $t^{*} = \lceil \log_2 N / \log_2 K \rceil$. Interestingly, this phenomenon is not observed in language, as its natural structure keeps the effective entropy per position well below the codebook capacity. To address this, we propose Variable Codebook Size Quantization (VCQ), where the codebook size $K_t$ grows monotonically along the sequence from $K_{\min}=2$ to $K_{\max}$, leaving the loss function, parameter count, and AR training procedure unchanged. With a vanilla autoregressive Transformer and standard next-token prediction, a base version of VCQ reduces gFID w/o CFG from 27.98 to 14.80 on ImageNet $256\times256$ over the baseline. Scaled up, it reaches gFID 1.71 with 684M autoregressive parameters, without any extra training techniques such as semantic regularization or causal alignment. The extreme information bottleneck at $K_{\min}=2$ naturally induces a coarse-to-fine semantic hierarchy: a linear probe on only the first 10 tokens reaches 43.8% top-1 accuracy on ImageNet, compared to 27.1% for uniform codebooks. Ultimately, these results show that what matters is not only the total capacity of the codebook, but also how that capacity is distributed and organized.

Yumeng Li, Guang Yang, Hao Liu et al.

Document Layout Parsing serves as a critical gateway for Artificial Intelligence (AI) to access and interpret the world's vast stores of structured knowledge. This process,which encompasses layout detection, text recognition, and relational understanding, is particularly crucial for empowering next-generation Vision-Language Models. Current methods, however, rely on fragmented, multi-stage pipelines that suffer from error propagation and fail to leverage the synergies of joint training. In this paper, we introduce dots.ocr, a single Vision-Language Model that, for the first time, demonstrates the advantages of jointly learning three core tasks within a unified, end-to-end framework. This is made possible by a highly scalable data engine that synthesizes a vast multilingual corpus, empowering the model to deliver robust performance across a wide array of tasks, encompassing diverse languages, layouts, and domains. The efficacy of our unified paradigm is validated by state-of-the-art performance on the comprehensive OmniDocBench. Furthermore, to catalyze research in global document intelligence, we introduce XDocParse, a challenging new benchmark spanning 126 languages. On this testbed, dots.ocr establishes a powerful new baseline, outperforming the next-best competitor by a remarkable +7.4 point margin and proving its unparalleled multilingual capabilities.

Yifei Wang, Weimin Bai, Colin Zhang et al.

In this paper, we unify more than 10 existing one-step diffusion distillation approaches, such as Diff-Instruct, DMD, SIM, SiD, $f$-distill, etc, inside a theory-driven framework which we name the \textbf{\emph{Uni-Instruct}}. Uni-Instruct is motivated by our proposed diffusion expansion theory of the $f$-divergence family. Then we introduce key theories that overcome the intractability issue of the original expanded $f$-divergence, resulting in an equivalent yet tractable loss that effectively trains one-step diffusion models by minimizing the expanded $f$-divergence family. The novel unification introduced by Uni-Instruct not only offers new theoretical contributions that help understand existing approaches from a high-level perspective but also leads to state-of-the-art one-step diffusion generation performances. On the CIFAR10 generation benchmark, Uni-Instruct achieves record-breaking Frechet Inception Distance (FID) values of \textbf{\emph{1.46}} for unconditional generation and \textbf{\emph{1.38}} for conditional generation. On the ImageNet-$64\times 64$ generation benchmark, Uni-Instruct achieves a new SoTA one-step generation FID of \textbf{\emph{1.02}}, which outperforms its 79-step teacher diffusion with a significant improvement margin of 1.33 (1.02 vs 2.35). We also apply Uni-Instruct on broader tasks like text-to-3D generation. For text-to-3D generation, Uni-Instruct gives decent results, which slightly outperforms previous methods, such as SDS and VSD, in terms of both generation quality and diversity. Both the solid theoretical and empirical contributions of Uni-Instruct will potentially help future studies on one-step diffusion distillation and knowledge transferring of diffusion models.