David Steel

Jonathan Frawley, Chris G. Willcocks, Maged Habib et al.

Macular holes are a common eye condition which result in visual impairment. We look at the application of deep convolutional neural networks to the problem of macular hole segmentation. We use the 3D U-Net architecture as a basis and experiment with a number of design variants. Manually annotating and measuring macular holes is time consuming and error prone. Previous automated approaches to macular hole segmentation take minutes to segment a single 3D scan. Our proposed model generates significantly more accurate segmentations in less than a second. We found that an approach of architectural simplification, by greatly simplifying the network capacity and depth, exceeds both expert performance and state-of-the-art models such as residual 3D U-Nets.

Jonathan Frawley, Chris G. Willcocks, Maged Habib et al.

This paper investigates the application of deep convolutional neural networks with prohibitively small datasets to the problem of macular edema segmentation. In particular, we investigate several different heavily regularized architectures. We find that, contrary to popular belief, neural architectures within this application setting are able to achieve close to human-level performance on unseen test images without requiring large numbers of training examples. Annotating these 3D datasets is difficult, with multiple criteria required. It takes an experienced clinician two days to annotate a single 3D image, whereas our trained model achieves similar performance in less than a second. We found that an approach which uses targeted dataset augmentation, alongside architectural simplification with an emphasis on residual design, has acceptable generalization performance - despite relying on fewer than 15 training examples.

Tong Wu, Gungor Polatkan, David Steel et al.

In this paper, computer-based techniques for stylistic analysis of paintings are applied to the five panels of the 14th century Peruzzi Altarpiece by Giotto di Bondone. Features are extracted by combining a dual-tree complex wavelet transform with a hidden Markov tree (HMT) model. Hierarchical clustering is used to identify stylistic keywords in image patches, and keyword frequencies are calculated for sub-images that each contains many patches. A generative hierarchical Bayesian model learns stylistic patterns of keywords; these patterns are then used to characterize the styles of the sub-images; this in turn, permits to discriminate between paintings. Results suggest that such unsupervised probabilistic topic models can be useful to distill characteristic elements of style.