Jiangang Chen

Yiman Liu, Xiaoxiang Han, Tongtong Liang et al.

This paper introduces the Efficient Decoupled Masked Autoencoder (EDMAE), a novel self-supervised method for recognizing standard views in pediatric echocardiography. EDMAE introduces a new proxy task based on the encoder-decoder structure. The EDMAE encoder is composed of a teacher and a student encoder. The teacher encoder extracts the potential representation of the masked image blocks, while the student encoder extracts the potential representation of the visible image blocks. The loss is calculated between the feature maps output by the two encoders to ensure consistency in the latent representations they extract. EDMAE uses pure convolution operations instead of the ViT structure in the MAE encoder. This improves training efficiency and convergence speed. EDMAE is pre-trained on a large-scale private dataset of pediatric echocardiography using self-supervised learning, and then fine-tuned for standard view recognition. The proposed method achieves high classification accuracy in 27 standard views of pediatric echocardiography. To further verify the effectiveness of the proposed method, the authors perform another downstream task of cardiac ultrasound segmentation on the public dataset CAMUS. The experimental results demonstrate that the proposed method outperforms some popular supervised and recent self-supervised methods, and is more competitive on different downstream tasks.

Yiman Liu, Qiming Huang, Xiaoxiang Han et al.

Purpose: Congenital heart defect (CHD) is the most common birth defect. Thoracic echocardiography (TTE) can provide sufficient cardiac structure information, evaluate hemodynamics and cardiac function, and is an effective method for atrial septal defect (ASD) examination. This paper aims to study a deep learning method based on cardiac ultrasound video to assist in ASD diagnosis. Materials and methods: We select two standard views of the atrial septum (subAS) and low parasternal four-compartment view (LPS4C) as the two views to identify ASD. We enlist data from 300 children patients as part of a double-blind experiment for five-fold cross-validation to verify the performance of our model. In addition, data from 30 children patients (15 positives and 15 negatives) are collected for clinician testing and compared to our model test results (these 30 samples do not participate in model training). We propose an echocardiography video-based atrial septal defect diagnosis system. In our model, we present a block random selection, maximal agreement decision and frame sampling strategy for training and testing respectively, resNet18 and r3D networks are used to extract the frame features and aggregate them to build a rich video-level representation. Results: We validate our model using our private dataset by five-cross validation. For ASD detection, we achieve 89.33 AUC, 84.95 accuracy, 85.70 sensitivity, 81.51 specificity and 81.99 F1 score. Conclusion: The proposed model is multiple instances learning-based deep learning model for video atrial septal defect detection which effectively improves ASD detection accuracy when compared to the performances of previous networks and clinical doctors.

Yung-Hong Sun, Gefei Shen, Jiangang Chen et al.

EasyVis2 is a system designed to provide hands-free, real-time 3D visualization for laparoscopic surgery. It incorporates a surgical trocar equipped with an array of micro-cameras, which can be inserted into the body cavity to offer an enhanced field of view and a 3D perspective of the surgical procedure. A specialized deep neural network algorithm, YOLOv8-Pose, is utilized to estimate the position and orientation of surgical instruments in each individual camera view. These multi-view estimates enable the calculation of 3D poses of surgical tools, facilitating the rendering of a 3D surface model of the instruments, overlaid on the background scene, for real-time visualization. This study presents methods for adapting YOLOv8-Pose to the EasyVis2 system, including the development of a tailored training dataset. Experimental results demonstrate that, with an identical number of cameras, the new system improves 3D reconstruction accuracy and reduces computation time. Additionally, the adapted YOLOv8-Pose system shows high accuracy in 2D pose estimation.

Xiaoxiang Han, Yiman Liu, Jiang Shang et al.

Segmenting internal structure from echocardiography is essential for the diagnosis and treatment of various heart diseases. Semi-supervised learning shows its ability in alleviating annotations scarcity. While existing semi-supervised methods have been successful in image segmentation across various medical imaging modalities, few have attempted to design methods specifically addressing the challenges posed by the poor contrast, blurred edge details and noise of echocardiography. These characteristics pose challenges to the generation of high-quality pseudo-labels in semi-supervised segmentation based on Mean Teacher. Inspired by human reflection on erroneous practices, we devise an error reflection strategy for echocardiography semi-supervised segmentation architecture. The process triggers the model to reflect on inaccuracies in unlabeled image segmentation, thereby enhancing the robustness of pseudo-label generation. Specifically, the strategy is divided into two steps. The first step is called reconstruction reflection. The network is tasked with reconstructing authentic proxy images from the semantic masks of unlabeled images and their auxiliary sketches, while maximizing the structural similarity between the original inputs and the proxies. The second step is called guidance correction. Reconstruction error maps decouple unreliable segmentation regions. Then, reliable data that are more likely to occur near high-density areas are leveraged to guide the optimization of unreliable data potentially located around decision boundaries. Additionally, we introduce an effective data augmentation strategy, termed as multi-scale mixing up strategy, to minimize the empirical distribution gap between labeled and unlabeled images and perceive diverse scales of cardiac anatomical structures. Extensive experiments demonstrate the competitiveness of the proposed method.

Jiangang Chen, Yung-Hong Sun, Kristen Pickett et al.

We developed a shoe-mounted gait monitoring system capable of tracking up to 17 gait parameters, including gait length, step time, stride velocity, and others. The system employs a stereo camera mounted on one shoe to track a marker placed on the opposite shoe, enabling the estimation of spatial gait parameters. Additionally, a Force Sensitive Resistor (FSR) affixed to the heel of the shoe, combined with a custom-designed algorithm, is utilized to measure temporal gait parameters. Through testing on multiple participants and comparison with the gait mat, the proposed gait monitoring system exhibited notable performance, with the accuracy of all measured gait parameters exceeding 93.61%. The system also demonstrated a low drift of 4.89% during long-distance walking. A gait identification task conducted on participants using a trained Transformer model achieved 95.7% accuracy on the dataset collected by the proposed system, demonstrating that our hardware has the potential to collect long-sequence gait data suitable for integration with current Large Language Models (LLMs). The system is cost-effective, user-friendly, and well-suited for real-life measurements.

Renxing Li, Weiyi Tang, Peiqi Li et al.

Objective. Elevated intracranial pressure (ICP) is recognized as a biomarker of secondary brain injury, with a significant linear correlation observed between optic nerve sheath diameter (ONSD) and ICP. Frequent monitoring of ONSD could effectively support dynamic evaluation of ICP. However, ONSD measurement is heavily reliant on the operator's experience and skill, particularly in manually selecting the optimal frame from ultrasound sequences and measuring ONSD. Approach. This paper presents a novel method to automatically identify the optimal frame from video sequences for ONSD measurement by employing the Kernel Correlation Filter (KCF) tracking algorithm and Simple Linear Iterative Clustering (SLIC) segmentation algorithm. The optic nerve sheath is mapped and measured using a Gaussian Mixture Model (GMM) combined with a KL-divergence-based method. Results. When compared with the average measurements of two expert clinicians, the proposed method achieved a mean error, mean squared deviation, and intraclass correlation coefficient (ICC) of 0.04, 0.054, and 0.782, respectively. Significance. The findings suggest that this method provides highly accurate automated ONSD measurements, showing potential for clinical application.

Jiayuan She, Lin Shi, Peiqi Li et al.

Background. Infectious diseases, particularly COVID-19, continue to be a significant global health issue. Although many countries have reduced or stopped large-scale testing measures, the detection of such diseases remains a propriety. Objective. This study aims to develop a novel, lightweight deep neural network for efficient, accurate, and cost-effective detection of COVID-19 using a nasal breathing audio data collected via smartphones. Methodology. Nasal breathing audio from 128 patients diagnosed with the Omicron variant was collected. Mel-Frequency Cepstral Coefficients (MFCCs), a widely used feature in speech and sound analysis, were employed for extracting important characteristics from the audio signals. Additional feature selection was performed using Random Forest (RF) and Principal Component Analysis (PCA) for dimensionality reduction. A Dense-ReLU-Dropout model was trained with K-fold cross-validation (K=3), and performance metrics like accuracy, precision, recall, and F1-score were used to evaluate the model. Results. The proposed model achieved 97% accuracy in detecting COVID-19 from nasal breathing sounds, outperforming state-of-the-art methods such as those by [23] and [13]. Our Dense-ReLU-Dropout model, using RF and PCA for feature selection, achieves high accuracy with greater computational efficiency compared to existing methods that require more complex models or larger datasets. Conclusion. The findings suggest that the proposed method holds significant potential for clinical implementation, advancing smartphone-based diagnostics in infectious diseases. The Dense-ReLU-Dropout model, combined with innovative feature processing techniques, offers a promising approach for efficient and accurate COVID-19 detection, showcasing the capabilities of mobile device-based diagnostics

Yung-Hong Sun, Ting-Hung Lin, Jiangang Chen et al.

Multi-view multi-instance feature association constitutes a crucial step in 3D reconstruction, facilitating the consistent grouping of object instances across various camera perspectives. The presence of multiple identical objects within a scene often leads to ambiguities for appearance-based feature matching algorithms. Our work circumvents this challenge by exclusively employing geometrical constraints, specifically epipolar geometry, for feature association. We introduce C-DOG (Connected delta-Overlap Graph), an algorithm designed for robust geometrical feature association, even in the presence of noisy feature detections. In a C-DOG graph, two nodes representing 2D feature points from distinct views are connected by an edge if they correspond to the same 3D point. Each edge is weighted by its epipolar distance. Ideally, true associations yield a zero distance; however, noisy feature detections can result in non-zero values. To robustly retain edges where the epipolar distance is less than a threshold delta, we employ a Szymkiewicz--Simpson coefficient. This process leads to a delta-neighbor-overlap clustering of 2D nodes. Furthermore, unreliable nodes are pruned from these clusters using an Inter-quartile Range (IQR)-based criterion. Our extensive experiments on synthetic benchmarks demonstrate that C-DOG not only outperforms geometry-based baseline algorithms but also remains remarkably robust under demanding conditions. This includes scenes with high object density, no visual features, and restricted camera overlap, positioning C-DOG as an excellent solution for scalable 3D reconstruction in practical applications.

Peiqi Li, Yincheng Gao, Renxing Li et al.

Heterogeneous morphological features and data imbalance pose significant challenges in rare thyroid carcinoma classification using ultrasound imaging. To address this issue, we propose a novel multitask learning framework, Channel-Spatial Attention Synergy Network (CSASN), which integrates a dual-branch feature extractor - combining EfficientNet for local spatial encoding and ViT for global semantic modeling, with a cascaded channel-spatial attention refinement module. A residual multiscale classifier and dynamically weighted loss function further enhance classification stability and accuracy. Trained on a multicenter dataset comprising more than 2000 patients from four clinical institutions, our framework leverages a residual multiscale classifier and dynamically weighted loss function to enhance classification stability and accuracy. Extensive ablation studies demonstrate that each module contributes significantly to model performance, particularly in recognizing rare subtypes such as FTC and MTC carcinomas. Experimental results show that CSASN outperforms existing single-stream CNN or Transformer-based models, achieving a superior balance between precision and recall under class-imbalanced conditions. This framework provides a promising strategy for AI-assisted thyroid cancer diagnosis.

Xiangyu Xiong, Yue Sun, Xiaohong Liu et al.

Despite the potential benefits of data augmentation for mitigating the data insufficiency, traditional augmentation methods primarily rely on the prior intra-domain knowledge. On the other hand, advanced generative adversarial networks (GANs) generate inter-domain samples with limited variety. These previous methods make limited contributions to describing the decision boundaries for binary classification. In this paper, we propose a distance guided GAN (DisGAN) which controls the variation degrees of generated samples in the hyperplane space. Specifically, we instantiate the idea of DisGAN by combining two ways. The first way is vertical distance GAN (VerDisGAN) where the inter-domain generation is conditioned on the vertical distances. The second way is horizontal distance GAN (HorDisGAN) where the intra-domain generation is conditioned on the horizontal distances. Furthermore, VerDisGAN can produce the class-specific regions by mapping the source images to the hyperplane. Experimental results show that DisGAN consistently outperforms the GAN-based augmentation methods with explainable binary classification. The proposed method can apply to different classification architectures and has potential to extend to multi-class classification.