Ayberk Acar

Hao Li, Daiwei Lu, Jesse d'Almeida et al.

Monocular depth estimation (MDE) is a critical task to guide autonomous medical robots. However, obtaining absolute (metric) depth from an endoscopy camera in surgical scenes is difficult, which limits supervised learning of depth on real endoscopic images. Current image-level unsupervised domain adaptation methods translate synthetic images with known depth maps into the style of real endoscopic frames and train depth networks using these translated images with their corresponding depth maps. However a domain gap often remains between real and translated synthetic images. In this paper, we present a latent feature alignment method to improve absolute depth estimation by reducing this domain gap in the context of endoscopic videos of the central airway. Our methods are agnostic to the image translation process and focus on the depth estimation itself. Specifically, the depth network takes translated synthetic and real endoscopic frames as input and learns latent domain-invariant features via adversarial learning and directional feature consistency. The evaluation is conducted on endoscopic videos of central airway phantoms with manually aligned absolute depth maps. Compared to state-of-the-art MDE methods, our approach achieves superior performance on both absolute and relative depth metrics, and consistently improves results across various backbones and pretrained weights. Our code is available at https://github.com/MedICL-VU/MDE.

Ayberk Acar, Mariana Smith, Lidia Al-Zogbi et al.

Surgical automation requires precise guidance and understanding of the scene. Current methods in the literature rely on bulky depth cameras to create maps of the anatomy, however this does not translate well to space-limited clinical applications. Monocular cameras are small and allow minimally invasive surgeries in tight spaces but additional processing is required to generate 3D scene understanding. We propose a 3D mapping pipeline that uses only RGB images to create segmented point clouds of the target anatomy. To ensure the most precise reconstruction, we compare different structure from motion algorithms' performance on mapping the central airway obstructions, and test the pipeline on a downstream task of tumor resection. In several metrics, including post-procedure tissue model evaluation, our pipeline performs comparably to RGB-D cameras and, in some cases, even surpasses their performance. These promising results demonstrate that automation guidance can be achieved in minimally invasive procedures with monocular cameras. This study is a step toward the complete autonomy of surgical robots.

Hao Yang, Ayberk Acar, Keshuai Xu et al.

Robot-assisted minimally invasive surgery, such as through the da Vinci systems, improves precision and patient outcomes. However, da Vinci systems prior to da Vinci 5, lacked direct force-sensing capabilities, forcing surgeons to operate without the haptic feedback they get through laparoscopy. Our prior work restored force sensing through machine learning-based force estimation for the da Vinci Research Kit (dVRK) Classic. This study extends our previous method to the newer dVRK system, the dVRK-Si. Additionally, we benchmark the performance of the learning-based algorithm against baseline methods (which make simplifying assumptions on the torque) to study how the two systems differ. Results show the learning-based method achieves an average root-mean-square-error (RMSE) of 5.21\%, for the dVRK-Si, which is comparable to the dVRK Classic. In both systems, the learning-based method outperforms baselines, but the difference is much larger in the dVRK-Si. Nonetheless, dVRK-Si force estimation accuracy lags behind the dVRK Classic, with RMSE 2 to 3 times higher. Further analysis reveals poor PID control in the dVRK-Si. We hypothesize that this is due to the lack of gravity compensation, as unlike the dVRK Classic, the dVRK-Si is not mechanically balanced. This study advances the understanding of learning-based force estimation and is the first work to characterize the dynamics of the new dVRK-Si system.

John J. Han, Ayberk Acar, Nicholas Kavoussi et al.

Style transfer is a promising approach to close the sim-to-real gap in medical endoscopy. Rendering synthetic endoscopic videos by traversing pre-operative scans (such as MRI or CT) can generate structurally accurate simulations as well as ground truth camera poses and depth maps. Although image-to-image (I2I) translation models such as CycleGAN can imitate realistic endoscopic images from these simulations, they are unsuitable for video-to-video synthesis due to the lack of temporal consistency, resulting in artifacts between frames. We propose MeshBrush, a neural mesh stylization method to synthesize temporally consistent videos with differentiable rendering. MeshBrush uses the underlying geometry of patient imaging data while leveraging existing I2I methods. With learned per-vertex textures, the stylized mesh guarantees consistency while producing high-fidelity outputs. We demonstrate that mesh stylization is a promising approach for creating realistic simulations for downstream tasks such as training networks and preoperative planning. Although our method is tested and designed for ureteroscopy, its components are transferable to general endoscopic and laparoscopic procedures. The code will be made public on GitHub.

Ayberk Acar, Fangjie Li, Hao Li et al.

Central airway obstruction (CAO) is a life-threatening condition with increasing incidence, caused by tumors in and outside of the airway. Traditional treatment methods such as bronchoscopy and electrocautery can be used to remove the tumor completely; however, these methods carry a high risk of complications. Recent advances allow robotic interventions with lesser risk. The combination of robot interventions with scene understanding and mapping also opens up the possibilities for automation. We present a novel pipeline that enables real-time, semantically informed 3D reconstructions of the central airway using monocular endoscopic video. Our approach combines DROID-SLAM with a segmentation model trained to identify obstructive tissues. The SLAM module reconstructs the 3D geometry of the airway in real time, while the segmentation masks guide the annotation of obstruction regions within the reconstructed point cloud. To validate our pipeline, we evaluate the reconstruction quality using ex vivo models. Qualitative and quantitative results show high similarity between ground truth CT scans and the 3D reconstructions (0.62 mm Chamfer distance). By integrating segmentation directly into the SLAM workflow, our system produces annotated 3D maps that highlight clinically relevant regions in real time. High-speed capabilities of the pipeline allows quicker reconstructions compared to previous work, reflecting the surgical scene more accurately. To the best of our knowledge, this is the first work to integrate semantic segmentation with real-time monocular SLAM for endoscopic CAO scenarios. Our framework is modular and can generalize to other anatomies or procedures with minimal changes, offering a promising step toward autonomous robotic interventions.