Won Hwa Kim

Deunsol Jung, Sanghyun Kim, Won Hwa Kim et al.

Scene graph generation aims to construct a semantic graph structure from an image such that its nodes and edges respectively represent objects and their relationships. One of the major challenges for the task lies in the presence of distracting objects and relationships in images; contextual reasoning is strongly distracted by irrelevant objects or backgrounds and, more importantly, a vast number of irrelevant candidate relations. To tackle the issue, we propose the Selective Quad Attention Network (SQUAT) that learns to select relevant object pairs and disambiguate them via diverse contextual interactions. SQUAT consists of two main components: edge selection and quad attention. The edge selection module selects relevant object pairs, i.e., edges in the scene graph, which helps contextual reasoning, and the quad attention module then updates the edge features using both edge-to-node and edge-to-edge cross-attentions to capture contextual information between objects and object pairs. Experiments demonstrate the strong performance and robustness of SQUAT, achieving the state of the art on the Visual Genome and Open Images v6 benchmarks.

Jiaqi Ding, Tingting Dan, Ziquan Wei et al.

An unprecedented amount of existing functional Magnetic Resonance Imaging (fMRI) data provides a new opportunity to understand the relationship between functional fluctuation and human cognition/behavior using a data-driven approach. To that end, tremendous efforts have been made in machine learning to predict cognitive states from evolving volumetric images of blood-oxygen-level-dependent (BOLD) signals. Due to the complex nature of brain function, however, the evaluation on learning performance and discoveries are not often consistent across current state-of-the-arts (SOTA). By capitalizing on large-scale existing neuroimaging data (34,887 data samples from six public databases), we seek to establish a well-founded empirical guideline for designing deep models for functional neuroimages by linking the methodology underpinning with knowledge from the neuroscience domain. Specifically, we put the spotlight on (1) What is the current SOTA performance in cognitive task recognition and disease diagnosis using fMRI? (2) What are the limitations of current deep models? and (3) What is the general guideline for selecting the suitable machine learning backbone for new neuroimaging applications? We have conducted a comprehensive evaluation and statistical analysis, in various settings, to answer the above outstanding questions.

Minjae Lee, Sungwoo Hur, Soojin Hwang et al.

Visual Foundation Models (VFMs) such as the Segment Anything Model (SAM) have significantly advanced broad use of image segmentation. However, SAM and its variants necessitate substantial manual effort for prompt generation and additional training for specific applications. Recent approaches address these limitations by integrating SAM into in-context (one/few shot) segmentation, enabling auto-prompting through semantic alignment between query and support images. Despite these efforts, they still generate sub-optimal prompts that degrade segmentation quality due to visual inconsistencies between support and query images. To tackle this limitation, we introduce PR-MaGIC (Prompt Refinement via Mask Decoder Gradient Flow for In-Context Segmentation), a training-free test-time framework that refines prompts via gradient flow derived from SAM's mask decoder. PR-MaGIC seamlessly integrates into in-context segmentation frameworks, being theoretically grounded yet practically stabilized through a simple top-1 selection strategy that ensures robust performance across samples. Extensive evaluations demonstrate that PR-MaGIC consistently improves segmentation quality across various benchmarks, effectively mitigating inadequate prompts without requiring additional training or architectural modifications.

Seongjae Kang, Dong Bok Lee, Juho Jung et al.

Automated structured radiology report generation (SRRG) from chest X-ray images offers significant potential to reduce workload of radiologists by generating reports in structured formats that ensure clarity, consistency, and adherence to clinical reporting standards. While radiologists effectively utilize available clinical contexts in their diagnostic reasoning, existing SRRG systems overlook these essential elements. This fundamental gap leads to critical problems including temporal hallucinations when referencing non-existent clinical contexts. To address these limitations, we propose contextualized SRRG (C-SRRG) that comprehensively incorporates rich clinical context for SRRG. We curate C-SRRG dataset by integrating comprehensive clinical context encompassing 1) multi-view X-ray images, 2) clinical indication, 3) imaging techniques, and 4) prior studies with corresponding comparisons based on patient histories. Through extensive benchmarking with state-of-the-art multimodal large language models, we demonstrate that incorporating clinical context with the proposed C-SRRG significantly improves report generation quality. We publicly release dataset, code, and checkpoints to facilitate future research for clinically-aligned automated RRG at https://github.com/vuno/contextualized-srrg.

Seunghun Baek, Jaeyoon Sim, Mustafa Dere et al.

Characterizing a preclinical stage of Alzheimer's Disease (AD) via single imaging is difficult as its early symptoms are quite subtle. Therefore, many neuroimaging studies are curated with various imaging modalities, e.g., MRI and PET, however, it is often challenging to acquire all of them from all subjects and missing data become inevitable. In this regards, in this paper, we propose a framework that generates unobserved imaging measures for specific subjects using their existing measures, thereby reducing the need for additional examinations. Our framework transfers modality-specific style while preserving AD-specific content. This is done by domain adversarial training that preserves modality-agnostic but AD-specific information, while a generative adversarial network adds an indistinguishable modality-specific style. Our proposed framework is evaluated on the Alzheimer's Disease Neuroimaging Initiative (ADNI) study and compared with other imputation methods in terms of generated data quality. Small average Cohen's $d$ $< 0.19$ between our generated measures and real ones suggests that the synthetic data are practically usable regardless of their modality type.

George R. Nahass, Zhu Wang, Homa Rashidisabet et al.

Machine unlearning aims to remove the influence of specific training samples from a trained model without full retraining. While prior work has largely focused on privacy-motivated settings, we recast unlearning as a general-purpose tool for post-deployment model revision. Specifically, we focus on utilizing unlearning in clinical contexts where data shifts, device deprecation, and policy changes are common. To this end, we propose a bilevel optimization formulation of boundary-based unlearning that can be solved using iterative algorithms. We provide convergence guarantees when first-order algorithms are used to unlearn. Our method introduces tunable loss design for controlling the forgetting-retention tradeoff and supports novel model composition strategies that merge the strengths of distinct unlearning runs. Across benchmark and real-world clinical imaging datasets, our approach outperforms baselines on both forgetting and retention metrics, including scenarios involving imaging devices and anatomical outliers. This work establishes machine unlearning as a modular, practical alternative to retraining for real-world model maintenance in clinical applications.

Yujee Song, Donghyun Lee, Rui Meng et al.

A Marked Temporal Point Process (MTPP) is a stochastic process whose realization is a set of event-time data. MTPP is often used to understand complex dynamics of asynchronous temporal events such as money transaction, social media, healthcare, etc. Recent studies have utilized deep neural networks to capture complex temporal dependencies of events and generate embedding that aptly represent the observed events. While most previous studies focus on the inter-event dependencies and their representations, how individual events influence the overall dynamics over time has been under-explored. In this regime, we propose a Decoupled MTPP framework that disentangles characterization of a stochastic process into a set of evolving influences from different events. Our approach employs Neural Ordinary Differential Equations (Neural ODEs) to learn flexible continuous dynamics of these influences while simultaneously addressing multiple inference problems, such as density estimation and survival rate computation. We emphasize the significance of disentangling the influences by comparing our framework with state-of-the-art methods on real-life datasets, and provide analysis on the model behavior for potential applications.

Xin Ma, Won Hwa Kim

Clustering algorithms have significantly improved along with Deep Neural Networks which provide effective representation of data. Existing methods are built upon deep autoencoder and self-training process that leverages the distribution of cluster assignments of samples. However, as the fundamental objective of the autoencoder is focused on efficient data reconstruction, the learnt space may be sub-optimal for clustering. Moreover, it requires highly effective codes (i.e., representation) of data, otherwise the initial cluster centers often cause stability issues during self-training. Many state-of-the-art clustering algorithms use convolution operation to extract efficient codes but their applications are limited to image data. In this regard, we propose an end-to-end deep clustering algorithm, i.e., Very Compact Clusters (VCC). VCC takes advantage of distributions of local relationships of samples near the boundary of clusters, so that they can be properly separated and pulled to cluster centers to form compact clusters. Experimental results on various datasets illustrate that our proposed approach achieves competitive clustering performance against most of the state-of-the-art clustering methods for both image and non-image data, and its results can be easily qualitatively seen in the learnt low-dimensional space.

Seong Jae Hwang, Zirui Tao, Won Hwa Kim et al.

Generative models using neural network have opened a door to large-scale studies for various application domains, especially for studies that suffer from lack of real samples to obtain statistically robust inference. Typically, these generative models would train on existing data to learn the underlying distribution of the measurements (e.g., images) in latent spaces conditioned on covariates (e.g., image labels), and generate independent samples that are identically distributed in the latent space. Such models may work for cross-sectional studies, however, they are not suitable to generate data for longitudinal studies that focus on "progressive" behavior in a sequence of data. In practice, this is a quite common case in various neuroimaging studies whose goal is to characterize a trajectory of pathologies of a specific disease even from early stages. This may be too ambitious especially when the sample size is small (e.g., up to a few hundreds). Motivated from the setup above, we seek to develop a conditional generative model for longitudinal data generation by designing an invertable neural network. Inspired by recurrent nature of longitudinal data, we propose a novel neural network that incorporates recurrent subnetwork and context gating to include smooth transition in a sequence of generated data. Our model is validated on a video sequence dataset and a longitudinal AD dataset with various experimental settings for qualitative and quantitative evaluations of the generated samples. The results with the AD dataset captures AD specific group differences with sufficiently generated longitudinal samples that are consistent with existing literature, which implies a great potential to be applicable to other disease studies.