Hanyu Chen

Yuanbo Xiangli, Hanyu Chen, Xueqing Tsang et al.

Metric scale monocular geometry estimation has seen significant progress through large-scale data aggregation, yet current foundation models suffer from a persistent ''scale-collapse'' phenomenon: distant landmarks and vast landscapes are metrically underestimated. We hypothesize that this performance gap stems from a training data bottleneck, where existing metric-scale datasets are hardware-constrained to homogenous vehicle-captured LiDAR or short-range indoor scans, or consist of synthetic data that lacks the semantic complexity of the physical world. To bridge this gap, we curate a new metrically-grounded, in-the-wild dataset that we call MetricScenes, gathered from a variety of sources including Internet photo collections and stereo imagery. We estimate camera poses and initial depth maps for each scene using off-the-shelf methods, and recover absolute scale from geo-tagged metadata as well as known stereo camera baselines. We also improve the quality of depth maps derived from MetricScenes via a new two-stage Poisson completion method. Fine-tuning MoGe-2 on our dataset significantly mitigates scale-collapse and achieves superior metric accuracy in unconstrained, open-domain scenes while maintaining state-of-the-art performance on standard benchmarks.

Hanyu Chen, Ruojin Cai, Steve Marschner et al.

Symmetry detection is a fundamental problem in computer vision, and symmetries serve as powerful priors for downstream tasks. However, existing learning-based methods for detecting 3D symmetries from single images have been almost exclusively trained and evaluated on object-centric or synthetic datasets, and thus fail to generalize to real-world scenes. Furthermore, due to the inherent scale ambiguity of monocular inputs, which makes localizing the 3D plane an ill-posed problem, many existing works only predict the plane's orientation. In this paper, we address these limitations by presenting the first framework for detecting 3D-grounded reflectional symmetries from single, in-the-wild RGB images, focusing on architectural landmarks. We introduce two key innovations: (1) a scalable data annotation pipeline to automatically curate a large-scale dataset of architectural symmetries, ArchSym, from SfM reconstructions by leveraging cross-view image matching; and building on the dataset, (2) a single-view symmetry detector that accurately localizes symmetries in 3D by parameterizing them as signed distance maps defined relative to predicted scene geometry. We validate our symmetry annotation pipeline against geometry-based alternatives and demonstrate that our symmetry detector significantly outperforms state-of-the-art baselines on our new benchmark.

Henrui Tian, Wenhui Lei, Linrui Dai et al.

Fully-supervised lesion recognition methods in medical imaging face challenges due to the reliance on large annotated datasets, which are expensive and difficult to collect. To address this, synthetic lesion generation has become a promising approach. However, existing models struggle with scalability, fine-grained control over lesion attributes, and the generation of complex structures. We propose LesionDiffusion, a text-controllable lesion synthesis framework for 3D CT imaging that generates both lesions and corresponding masks. By utilizing a structured lesion report template, our model provides greater control over lesion attributes and supports a wider variety of lesion types. We introduce a dataset of 1,505 annotated CT scans with paired lesion masks and structured reports, covering 14 lesion types across 8 organs. LesionDiffusion consists of two components: a lesion mask synthesis network (LMNet) and a lesion inpainting network (LINet), both guided by lesion attributes and image features. Extensive experiments demonstrate that LesionDiffusion significantly improves segmentation performance, with strong generalization to unseen lesion types and organs, outperforming current state-of-the-art models. Code is available at https://github.com/HengruiTianSJTU/LesionDiffusion.

Zhuokang Shen, Yifan Wang, Hanyu Chen et al.

Recent advances in large language models (LLMs) have enabled increasingly capable chatbots. However, most existing systems focus on single-user settings and do not generalize well to multi-user group chats, where agents require more proactive and accurate intervention under complex, evolving contexts. Existing approaches typically rely on LLMs for both reasoning and generation, leading to high token consumption, limited scalability, and potential privacy risks. To address these challenges, we propose GroupGPT, a token-efficient and privacy-preserving agentic framework for multi-user chat assistant. GroupGPT adopts a small-large model collaborative architecture to decouple intervention timing from response generation, enabling efficient and accurate decision-making. The framework also supports multimodal inputs, including memes, images, videos, and voice messages. We further introduce MUIR, a benchmark dataset for multi-user chat assistant intervention reasoning. MUIR contains 2,500 annotated group chat segments with intervention labels and rationales, supporting evaluation of timing accuracy and response quality. We evaluate a range of models on MUIR, from large language models to smaller counterparts. Extensive experiments demonstrate that GroupGPT produces accurate and well-timed responses, achieving an average score of 4.72/5.0 in LLM-based evaluation, and is well received by users across diverse group chat scenarios. Moreover, GroupGPT reduces token usage by up to 3 times compared to baseline methods, while providing privacy sanitization of user messages before cloud transmission. Code is available at: https://github.com/Eliot-Shen/GroupGPT .

Wenhui Lei, Anqi Li, Yusheng Tan et al.

Foundation Models (FMs) in computational pathology (CPath) have significantly advanced the extraction of meaningful features from histopathology image datasets, achieving strong performance across various clinical tasks. Despite their impressive performance, these models often exhibit variability when applied to different tasks, prompting the need for a unified framework capable of consistently excelling across various applications. In this work, we propose Shazam, a novel framework designed to efficiently combine multiple CPath models. Unlike previous approaches that train a fixed-parameter FM, Shazam dynamically extracts and refines information from diverse FMs for each specific task. To ensure that each FM contributes effectively without dominance, a novel distillation strategy is applied, guiding the student model with features from all teacher models, which enhances its generalization ability. Experimental results on two pathology patch classification datasets demonstrate that Shazam outperforms existing CPath models and other fusion methods. Its lightweight, flexible design makes it a promising solution for improving CPath analysis in real-world settings. Code will be available at https://github.com/Tuner12/Shazam.

Max W. Y. Lam, Yijin Xing, Weiya You et al.

Autoregressive (AR) models have demonstrated impressive capabilities in generating high-fidelity music. However, the conventional next-token prediction paradigm in AR models does not align with the human creative process in music composition, potentially compromising the musicality of generated samples. To overcome this limitation, we introduce MusiCoT, a novel chain-of-thought (CoT) prompting technique tailored for music generation. MusiCoT empowers the AR model to first outline an overall music structure before generating audio tokens, thereby enhancing the coherence and creativity of the resulting compositions. By leveraging the contrastive language-audio pretraining (CLAP) model, we establish a chain of "musical thoughts", making MusiCoT scalable and independent of human-labeled data, in contrast to conventional CoT methods. Moreover, MusiCoT allows for in-depth analysis of music structure, such as instrumental arrangements, and supports music referencing -- accepting variable-length audio inputs as optional style references. This innovative approach effectively addresses copying issues, positioning MusiCoT as a vital practical method for music prompting. Our experimental results indicate that MusiCoT consistently achieves superior performance across both objective and subjective metrics, producing music quality that rivals state-of-the-art generation models. Our samples are available at https://MusiCoT.github.io/.

Bailey Miller, Hanyu Chen, Alice Lai et al.

We develop a theory for the representation of opaque solids as volumes. Starting from a stochastic representation of opaque solids as random indicator functions, we prove the conditions under which such solids can be modeled using exponential volumetric transport. We also derive expressions for the volumetric attenuation coefficient as a functional of the probability distributions of the underlying indicator functions. We generalize our theory to account for isotropic and anisotropic scattering at different parts of the solid, and for representations of opaque solids as stochastic implicit surfaces. We derive our volumetric representation from first principles, which ensures that it satisfies physical constraints such as reciprocity and reversibility. We use our theory to explain, compare, and correct previous volumetric representations, as well as propose meaningful extensions that lead to improved performance in 3D reconstruction tasks.

Yongrui Yu, Hanyu Chen, Zitian Zhang et al.

Despite the significant success achieved by deep learning methods in medical image segmentation, researchers still struggle in the computer-aided diagnosis of abdominal lymph nodes due to the complex abdominal environment, small and indistinguishable lesions, and limited annotated data. To address these problems, we present a pipeline that integrates the conditional diffusion model for lymph node generation and the nnU-Net model for lymph node segmentation to improve the segmentation performance of abdominal lymph nodes through synthesizing a diversity of realistic abdominal lymph node data. We propose LN-DDPM, a conditional denoising diffusion probabilistic model (DDPM) for lymph node (LN) generation. LN-DDPM utilizes lymph node masks and anatomical structure masks as model conditions. These conditions work in two conditioning mechanisms: global structure conditioning and local detail conditioning, to distinguish between lymph nodes and their surroundings and better capture lymph node characteristics. The obtained paired abdominal lymph node images and masks are used for the downstream segmentation task. Experimental results on the abdominal lymph node datasets demonstrate that LN-DDPM outperforms other generative methods in the abdominal lymph node image synthesis and better assists the downstream abdominal lymph node segmentation task.

Wenhui Lei, Hanyu Chen, Zitian Zhang et al.

AI-assisted imaging made substantial advances in tumor diagnosis and management. However, a major barrier to developing robust oncology foundation models is the scarcity of large-scale, high-quality annotated datasets, which are limited by privacy restrictions and the high cost of manual labeling. To address this gap, we present PASTA, a pan-tumor radiology foundation model built on PASTA-Gen, a synthetic data framework that generated 30,000 3D CT scans with pixel-level lesion masks and structured reports of tumors across ten organ systems. Leveraging this resource, PASTA achieves state-of-the-art performance on 45 of 46 oncology tasks, including non-contrast CT tumor screening, lesion segmentation, structured reporting, tumor staging, survival prediction, and MRI-modality transfer. To assess clinical applicability, we developed PASTA-AID, a clinical decision support system, and ran a retrospective simulated clinical trial across two scenarios. For pan-tumor screening on plain CT with fixed reading time, PASTA-AID increased radiologists' throughput by 11.1-25.1% and improved sensitivity by 17.0-31.4% and precision by 10.5-24.9%; additionally, in a diagnosis-aid workflow, it reduced segmentation time by up to 78.2% and reporting time by up to 36.5%. Beyond gains in accuracy and efficiency, PASTA-AID narrowed the expertise gap, enabling less-experienced radiologists to approach expert-level performance. Together, this work establishes an end-to-end, synthetic data-driven pipeline spanning data generation, model development, and clinical validation, thereby demonstrating substantial potential for pan-tumor research and clinical translation.

Hanyu Chen, Zhixiu Hao, Liying Xiao

Diffusion models have become a successful approach for solving various image inverse problems by providing a powerful diffusion prior. Many studies tried to combine the measurement into diffusion by score function replacement, matrix decomposition, or optimization algorithms, but it is hard to balance the data consistency and realness. The slow sampling speed is also a main obstacle to its wide application. To address the challenges, we propose Deep Data Consistency (DDC) to update the data consistency step with a deep learning model when solving inverse problems with diffusion models. By analyzing existing methods, the variational bound training objective is used to maximize the conditional posterior and reduce its impact on the diffusion process. In comparison with state-of-the-art methods in linear and non-linear tasks, DDC demonstrates its outstanding performance of both similarity and realness metrics in generating high-quality solutions with only 5 inference steps in 0.77 seconds on average. In addition, the robustness of DDC is well illustrated in the experiments across datasets, with large noise and the capacity to solve multiple tasks in only one pre-trained model.

Yuanbo Xiangli, Ruojin Cai, Hanyu Chen et al. · deepmind

Accurate 3D reconstruction is frequently hindered by visual aliasing, where visually similar but distinct surfaces (aka, doppelgangers), are incorrectly matched. These spurious matches distort the structure-from-motion (SfM) process, leading to misplaced model elements and reduced accuracy. Prior efforts addressed this with CNN classifiers trained on curated datasets, but these approaches struggle to generalize across diverse real-world scenes and can require extensive parameter tuning. In this work, we present Doppelgangers++, a method to enhance doppelganger detection and improve 3D reconstruction accuracy. Our contributions include a diversified training dataset that incorporates geo-tagged images from everyday scenes to expand robustness beyond landmark-based datasets. We further propose a Transformer-based classifier that leverages 3D-aware features from the MASt3R model, achieving superior precision and recall across both in-domain and out-of-domain tests. Doppelgangers++ integrates seamlessly into standard SfM and MASt3R-SfM pipelines, offering efficiency and adaptability across varied scenes. To evaluate SfM accuracy, we introduce an automated, geotag-based method for validating reconstructed models, eliminating the need for manual inspection. Through extensive experiments, we demonstrate that Doppelgangers++ significantly enhances pairwise visual disambiguation and improves 3D reconstruction quality in complex and diverse scenarios.

Joy Xiaoji Zhang, Jingsen Zhu, Hanyu Chen et al.

Simulating hair dynamics that generalize across arbitrary hairstyles, body shapes, and motions is a critical challenge. Our novel two-stage neural solution is the first to leverage Transformer-based architectures for such a broad generalization. We propose a Transformer-powered static network that predicts static draped shapes for any hairstyle, effectively resolving hair-body penetrations and preserving hair fidelity. Subsequently, a dynamic network with a novel cross-attention mechanism fuses static hair features with kinematic input to generate expressive dynamics and complex secondary motions. This dynamic network also allows for efficient fine-tuning of challenging motion sequences, such as abrupt head movements. Our method offers real-time inference for both static single-frame drapes and dynamic drapes over pose sequences. Our method demonstrates high-fidelity and generalizable dynamic hair across various styles, guided by physics-informed losses, and can resolve penetrations even for complex, unseen long hairstyles, highlighting its broad generalization.

Yannian Gu, Wenhui Lei, Hanyu Chen et al.

Automated CT report generation plays a crucial role in improving diagnostic accuracy and clinical workflow efficiency. However, existing methods lack interpretability and impede patient-clinician understanding, while their static nature restricts radiologists from dynamically adjusting assessments during image review. Inspired by interactive segmentation techniques, we propose a novel interactive framework for 3D lesion morphology reporting that seamlessly generates segmentation masks with comprehensive attribute descriptions, enabling clinicians to generate detailed lesion profiles for enhanced diagnostic assessment. To our best knowledge, we are the first to integrate the interactive segmentation and structured reports in 3D CT medical images. Experimental results across 15 lesion types demonstrate the effectiveness of our approach in providing a more comprehensive and reliable reporting system for lesion segmentation and capturing. The source code will be made publicly available following paper acceptance.

Hanyu Chen, Zhixiu Hao, Lin Guo et al.

Sparse-view Computed Tomography (CT) image reconstruction is a promising approach to reduce radiation exposure, but it inevitably leads to image degradation. Although diffusion model-based approaches are computationally expensive and suffer from the training-sampling discrepancy, they provide a potential solution to the problem. This study introduces a novel Cascaded Diffusion with Discrepancy Mitigation (CDDM) framework, including the low-quality image generation in latent space and the high-quality image generation in pixel space which contains data consistency and discrepancy mitigation in a one-step reconstruction process. The cascaded framework minimizes computational costs by moving some inference steps from pixel space to latent space. The discrepancy mitigation technique addresses the training-sampling gap induced by data consistency, ensuring the data distribution is close to the original manifold. A specialized Alternating Direction Method of Multipliers (ADMM) is employed to process image gradients in separate directions, offering a more targeted approach to regularization. Experimental results across two datasets demonstrate CDDM's superior performance in high-quality image generation with clearer boundaries compared to existing methods, highlighting the framework's computational efficiency.

Wen Zhang, Dengji Zhao, Hanyu Chen

Redistribution mechanisms have been proposed for more efficient resource allocation but not for profit. We consider redistribution mechanism design in a setting where participants are connected and the resource owner is only connected to some of them. In this setting, to make the resource allocation more efficient, the resource owner has to inform the others who are not her neighbours, but her neighbours do not want more participants to compete with them. Hence, the goal is to design a redistribution mechanism such that participants are incentivized to invite more participants and the resource owner does not earn or lose much money from the allocation. We first show that existing redistribution mechanisms cannot be directly applied in the network setting and prove the impossibility to achieve efficiency without a deficit. Then we propose a novel network-based redistribution mechanism such that all participants on the network are invited, the allocation is more efficient and the resource owner has no deficit.