Roman Naeem

David Hagerman, Roman Naeem, Jakob Lindqvist et al.

Sparse vision transformers have gained popularity as efficient encoders for medical volumetric segmentation, with Swin emerging as a prominent choice. Swin uses local attention to reduce complexity and yields excellent performance for many tasks but still tends to overfit on small datasets. To mitigate this weakness, we propose a novel architecture that further enhances Swin's inductive bias by introducing Inception blocks in the feed-forward layers. The introduction of these multi-branch convolutions enables more direct reasoning over local, multi-scale features within the transformer block. We have also modified the decoder layers in order to capture finer details using fewer parameters. We demonstrate a performance improvement on eleven different medical datasets through extensive experimentation. We specifically showcase advancements over the previous state-of-the-art backbones on benchmark challenges like the Medical Segmentation Decathlon and Beyond the Cranial Vault. By showing that the existing inductive bias in Swin can be further improved, our work presents a promising avenue for enhancing the capabilities of sparse vision transformers for both medical and natural image segmentation tasks. Code and pre-trained weights can be accessed at https://github.com/Eiphodos/SwInception.

David Hagerman, Roman Naeem, Erik Brorsson et al.

We present ARTA, a mixed-resolution coarse-to-fine vision transformer for efficient dense feature extraction. Unlike models that begin with dense high-resolution (fine) tokens, ARTA starts with low-resolution (coarse) tokens and uses a lightweight allocator to predict which regions require more fine tokens. The allocator iteratively predicts a semantic (class) boundary score and allocates additional tokens to patches above a low threshold, concentrating token density near boundaries while maintaining high sensitivity to weak boundary evidence. This targeted allocation encourages tokens to represent a single semantic class rather than a mixture of classes. Mixed-resolution attention enables interaction between coarse and fine tokens, focusing computation on semantically complex areas while avoiding redundant processing in homogeneous regions. Experiments demonstrate that ARTA achieves state-of-the-art results on ADE20K and COCO-Stuff with substantially fewer FLOPs, and delivers competitive performance on Cityscapes at markedly lower compute. For example, ARTA-Base attains 54.6 mIoU on ADE20K in the ~100M-parameter class while using fewer FLOPs and less memory than comparable backbones.

Roman Naeem, David Hagerman, Jennifer Alvén et al.

Tubular tree structures, such as blood vessels and airways, are essential in human anatomy and accurately tracking them while preserving their topology is crucial for various downstream tasks. Trexplorer is a recurrent model designed for centerline tracking in 3D medical images but it struggles with predicting duplicate branches and terminating tracking prematurely. To address these issues, we present Trexplorer Super, an enhanced version that notably improves performance through novel advancements. However, evaluating centerline tracking models is challenging due to the lack of public datasets. To enable thorough evaluation, we develop three centerline datasets, one synthetic and two real, each with increasing difficulty. Using these datasets, we conduct a comprehensive evaluation of existing state-of-the-art (SOTA) models and compare them with our approach. Trexplorer Super outperforms previous SOTA models on every dataset. Our results also highlight that strong performance on synthetic data does not necessarily translate to real datasets. The code and datasets are available at https://github.com/RomStriker/Trexplorer-Super.

David Hagerman, Anna Johnning, Roman Naeem et al.

Antibiotic Resistance (AR) is a critical global health challenge that necessitates the development of cost-effective, efficient, and accurate diagnostic tools. Given the genetic basis of AR, techniques such as Polymerase Chain Reaction (PCR) that target specific resistance genes offer a promising approach for predictive diagnostics using a limited set of key genes. This study introduces GenoARM, a novel framework that integrates reinforcement learning (RL) with transformer-based models to optimize the selection of PCR gene tests and improve AR predictions, leveraging observed metadata for improved accuracy. In our evaluation, we developed several high-performing baselines and compared them using publicly available datasets derived from real-world bacterial samples representing multiple clinically relevant pathogens. The results show that all evaluated methods achieve strong and reliable performance when metadata is not utilized. When metadata is introduced and the number of selected genes increases, GenoARM demonstrates superior performance due to its capacity to approximate rewards for unseen and sparse combinations. Overall, our framework represents a major advancement in optimizing diagnostic tools for AR in clinical settings.

Roman Naeem, David Hagerman, Jennifer Alvén et al.

Tubular trees, such as blood vessels and lung airways, are essential for material transport within the human body. Accurately detecting their centerlines with correct tree topology is critical for clinical tasks such as diagnosis, treatment planning, and surgical navigation. In these applications, maintaining high recall is crucial, as missing small branches can result in fatal mistakes caused by incomplete assessments or undetected abnormalities. We present RefTr, a 3D image-to-graph model for centerline generation of vascular trees via recurrent refinement of confluent trajectories. RefTr uses a Producer-Refiner architecture based on a Transformer decoder, where the Producer proposes a set of initial confluent trajectories that are recurrently refined by the Refiner to produce final trajectories, which forms the centerline graph. The confluent trajectory representation enables refinement of complete trajectories while explicitly enforcing a valid tree topology. The recurrent refinement scheme improves precision and reuses the same Refiner block across multiple steps, yielding a 2.4x reduction in decoder parameters compared to previous SOTA. We also introduce an efficient non-maximum suppression algorithm for spatial tree graphs to merge duplicate branches and boost precision. Across multiple public centerline datasets, RefTr achieves superior recall and comparable precision to previous SOTA, while offering faster inference and substantially fewer parameters, demonstrating its potential as a new state-of-the-art framework for vascular tree analysis in 3D medical imaging.