Bang Du

Weize Liu, Guocong Li, Kai Zhang et al.

Large language models (LLMs) have achieved remarkable advancements in natural language processing. However, the massive scale and computational demands of these models present formidable challenges when considering their practical deployment in resource-constrained environments. While techniques such as chain-of-thought (CoT) distillation have displayed promise in distilling LLMs into small language models (SLMs), there is a risk that distilled SLMs may still inherit flawed reasoning and hallucinations from LLMs. To address these issues, we propose a twofold methodology: First, we introduce a novel method for distilling the self-evaluation capability from LLMs into SLMs, aiming to mitigate the adverse effects of flawed reasoning and hallucinations inherited from LLMs. Second, we advocate for distilling more comprehensive thinking by incorporating multiple distinct CoTs and self-evaluation outputs, to ensure a more thorough and robust knowledge transfer into SLMs. Experiments on three NLP benchmarks demonstrate that our method significantly improves the performance of distilled SLMs, offering a new perspective for developing more effective and efficient SLMs in resource-constrained environments.

Kien Nguyen, Subarna Tripathi, Bang Du et al.

The mainstream image captioning models rely on Convolutional Neural Network (CNN) image features to generate captions via recurrent models. Recently, image scene graphs have been used to augment captioning models so as to leverage their structural semantics, such as object entities, relationships and attributes. Several studies have noted that the naive use of scene graphs from a black-box scene graph generator harms image captioning performance and that scene graph-based captioning models have to incur the overhead of explicit use of image features to generate decent captions. Addressing these challenges, we propose \textbf{SG2Caps}, a framework that utilizes only the scene graph labels for competitive image captioning performance. The basic idea is to close the semantic gap between the two scene graphs - one derived from the input image and the other from its caption. In order to achieve this, we leverage the spatial location of objects and the Human-Object-Interaction (HOI) labels as an additional HOI graph. SG2Caps outperforms existing scene graph-only captioning models by a large margin, indicating scene graphs as a promising representation for image captioning. Direct utilization of scene graph labels avoids expensive graph convolutions over high-dimensional CNN features resulting in 49% fewer trainable parameters. Our code is available at: https://github.com/Kien085/SG2Caps

Yue Wang, Tianfan Fu, Yinlong Xu et al.

Clinical trials are indispensable for medical research and the development of new treatments. However, clinical trials often involve thousands of participants and can span several years to complete, with a high probability of failure during the process. Recently, there has been a burgeoning interest in virtual clinical trials, which simulate real-world scenarios and hold the potential to significantly enhance patient safety, expedite development, reduce costs, and contribute to the broader scientific knowledge in healthcare. Existing research often focuses on leveraging electronic health records (EHRs) to support clinical trial outcome prediction. Yet, trained with limited clinical trial outcome data, existing approaches frequently struggle to perform accurate predictions. Some research has attempted to generate EHRs to augment model development but has fallen short in personalizing the generation for individual patient profiles. Recently, the emergence of large language models has illuminated new possibilities, as their embedded comprehensive clinical knowledge has proven beneficial in addressing medical issues. In this paper, we propose a large language model-based digital twin creation approach, called TWIN-GPT. TWIN-GPT can establish cross-dataset associations of medical information given limited data, generating unique personalized digital twins for different patients, thereby preserving individual patient characteristics. Comprehensive experiments show that using digital twins created by TWIN-GPT can boost the clinical trial outcome prediction, exceeding various previous prediction approaches.

Jiancheng Yang, Rui Shi, Liang Jin et al. · harvard

Rib fractures are a common and potentially severe injury that can be challenging and labor-intensive to detect in CT scans. While there have been efforts to address this field, the lack of large-scale annotated datasets and evaluation benchmarks has hindered the development and validation of deep learning algorithms. To address this issue, the RibFrac Challenge was introduced, providing a benchmark dataset of over 5,000 rib fractures from 660 CT scans, with voxel-level instance mask annotations and diagnosis labels for four clinical categories (buckle, nondisplaced, displaced, or segmental). The challenge includes two tracks: a detection (instance segmentation) track evaluated by an FROC-style metric and a classification track evaluated by an F1-style metric. During the MICCAI 2020 challenge period, 243 results were evaluated, and seven teams were invited to participate in the challenge summary. The analysis revealed that several top rib fracture detection solutions achieved performance comparable or even better than human experts. Nevertheless, the current rib fracture classification solutions are hardly clinically applicable, which can be an interesting area in the future. As an active benchmark and research resource, the data and online evaluation of the RibFrac Challenge are available at the challenge website. As an independent contribution, we have also extended our previous internal baseline by incorporating recent advancements in large-scale pretrained networks and point-based rib segmentation techniques. The resulting FracNet+ demonstrates competitive performance in rib fracture detection, which lays a foundation for further research and development in AI-assisted rib fracture detection and diagnosis.

Keito Suzuki, Bang Du, Girish Krishnan et al.

3D part segmentation is still an open problem in the field of 3D vision and AR/VR. Due to limited 3D labeled data, traditional supervised segmentation methods fall short in generalizing to unseen shapes and categories. Recently, the advancement in vision-language models' zero-shot abilities has brought a surge in open-world 3D segmentation methods. While these methods show promising results for 3D scenes or objects, they do not generalize well to 3D humans. In this paper, we present the first open-vocabulary segmentation method capable of handling 3D human. Our framework can segment the human category into desired fine-grained parts based on the textual prompt. We design a simple segmentation pipeline, leveraging SAM to generate multi-view proposals in 2D and proposing a novel HumanCLIP model to create unified embeddings for visual and textual inputs. Compared with existing pre-trained CLIP models, the HumanCLIP model yields more accurate embeddings for human-centric contents. We also design a simple-yet-effective MaskFusion module, which classifies and fuses multi-view features into 3D semantic masks without complex voting and grouping mechanisms. The design of decoupling mask proposals and text input also significantly boosts the efficiency of per-prompt inference. Experimental results on various 3D human datasets show that our method outperforms current state-of-the-art open-vocabulary 3D segmentation methods by a large margin. In addition, we show that our method can be directly applied to various 3D representations including meshes, point clouds, and 3D Gaussian Splatting.

Runfa Blark Li, Keito Suzuki, Bang Du et al.

A signed distance function (SDF) is a useful representation for continuous-space geometry and many related operations, including rendering, collision checking, and mesh generation. Hence, reconstructing SDF from image observations accurately and efficiently is a fundamental problem. Recently, neural implicit SDF (SDF-NeRF) techniques, trained using volumetric rendering, have gained a lot of attention. Compared to earlier truncated SDF (TSDF) fusion algorithms that rely on depth maps and voxelize continuous space, SDF-NeRF enables continuous-space SDF reconstruction with better geometric and photometric accuracy. However, the accuracy and convergence speed of scene-level SDF reconstruction require further improvements for many applications. With the advent of 3D Gaussian Splatting (3DGS) as an explicit representation with excellent rendering quality and speed, several works have focused on improving SDF-NeRF by introducing consistency losses on depth and surface normals between 3DGS and SDF-NeRF. However, loss-level connections alone lead to incremental improvements. We propose a novel neural implicit SDF called "SplatSDF" to fuse 3DGSandSDF-NeRF at an architecture level with significant boosts to geometric and photometric accuracy and convergence speed. Our SplatSDF relies on 3DGS as input only during training, and keeps the same complexity and efficiency as the original SDF-NeRF during inference. Our method outperforms state-of-the-art SDF-NeRF models on geometric and photometric evaluation by the time of submission.

Runfa Blark Li, Mahdi Shaghaghi, Keito Suzuki et al.

Simultaneous Localization and Mapping (SLAM) is one of the most important environment-perception and navigation algorithms for computer vision, robotics, and autonomous cars/drones. Hence, high quality and fast mapping becomes a fundamental problem. With the advent of 3D Gaussian Splatting (3DGS) as an explicit representation with excellent rendering quality and speed, state-of-the-art (SOTA) works introduce GS to SLAM. Compared to classical pointcloud-SLAM, GS-SLAM generates photometric information by learning from input camera views and synthesize unseen views with high-quality textures. However, these GS-SLAM fail when moving objects occupy the scene that violate the static assumption of bundle adjustment. The failed updates of moving GS affects the static GS and contaminates the full map over long frames. Although some efforts have been made by concurrent works to consider moving objects for GS-SLAM, they simply detect and remove the moving regions from GS rendering ("anti'' dynamic GS-SLAM), where only the static background could benefit from GS. To this end, we propose the first real-time GS-SLAM, "DynaGSLAM'', that achieves high-quality online GS rendering, tracking, motion predictions of moving objects in dynamic scenes while jointly estimating accurate ego motion. Our DynaGSLAM outperforms SOTA static & "Anti'' dynamic GS-SLAM on three dynamic real datasets, while keeping speed and memory efficiency in practice.

Xuecheng Chen, Zongzhuo Liu, Jianfa Ma et al.

Recent advances in large Vision-Language Models (VLMs) have provided rich semantic understanding that empowers drones to search for open-set objects via natural language instructions. However, prior systems struggle to integrate VLMs into practical aerial systems due to orders-of-magnitude frequency mismatch between VLM inference and real-time planning, as well as VLMs' limited 3D scene understanding. They also lack a unified mechanism to balance semantic guidance with motion efficiency in large-scale environments. To address these challenges, we present AirHunt, an aerial object navigation system that efficiently locates open-set objects with zero-shot generalization in outdoor environments by seamlessly fusing VLM semantic reasoning with continuous path planning. AirHunt features a dual-pathway asynchronous architecture that establishes a synergistic interface between VLM reasoning and path planning, enabling continuous flight with adaptive semantic guidance that evolves through motion. Moreover, we propose an active dual-task reasoning module that exploits geometric and semantic redundancy to enable selective VLM querying, and a semantic-geometric coherent planning module that dynamically reconciles semantic priorities and motion efficiency in a unified framework, enabling seamless adaptation to environmental heterogeneity. We evaluate AirHunt across diverse object navigation tasks and environments, demonstrating a higher success rate with lower navigation error and reduced flight time compared to state-of-the-art methods. Real-world experiments further validate AirHunt's practical capability in complex and challenging environments. Code and dataset will be made publicly available before publication.

Bang Du, Runfa Blark Li, Chen Du et al.

The reconstruction of 3D objects from calibrated photographs represents a fundamental yet intricate challenge in the domains of computer graphics and vision. Although neural reconstruction approaches based on Neural Radiance Fields (NeRF) have shown remarkable capabilities, their processing costs remain substantial. Recently, the advent of 3D Gaussian Splatting (3D-GS) largely improves the training efficiency and facilitates to generate realistic rendering in real-time. However, due to the limited ability of Spherical Harmonics (SH) to represent high-frequency information, 3D-GS falls short in reconstructing glossy objects. Researchers have turned to enhance the specular expressiveness of 3D-GS through inverse rendering. Yet these methods often struggle to maintain the training and rendering efficiency, undermining the benefits of Gaussian Splatting techniques. In this paper, we introduce GlossGau, an efficient inverse rendering framework that reconstructs scenes with glossy surfaces while maintaining training and rendering speeds comparable to vanilla 3D-GS. Specifically, we explicitly model the surface normals, Bidirectional Reflectance Distribution Function (BRDF) parameters, as well as incident lights and use Anisotropic Spherical Gaussian (ASG) to approximate the per-Gaussian Normal Distribution Function under the microfacet model. We utilize 2D Gaussian Splatting (2D-GS) as foundational primitives and apply regularization to significantly alleviate the normal estimation challenge encountered in related works. Experiments demonstrate that GlossGau achieves competitive or superior reconstruction on datasets with glossy surfaces. Compared with previous GS-based works that address the specular surface, our optimization time is considerably less.

Keito Suzuki, Bang Du, Runfa Blark Li et al.

Understanding dynamic 3D human representation has become increasingly critical in virtual and extended reality applications. However, existing human part segmentation methods are constrained by reliance on closed-set datasets and prolonged inference times, which significantly restrict their applicability. In this paper, we introduce the first 4D human parsing framework that simultaneously addresses these challenges by reducing the inference time and introducing open-vocabulary capabilities. Building upon state-of-the-art open-vocabulary 3D human parsing techniques, our approach extends the support to 4D human-centric video with three key innovations: 1) We adopt mask-based video object tracking to efficiently establish spatial and temporal correspondences, avoiding the necessity of segmenting all frames. 2) A novel Mask Validation module is designed to manage new target identification and mitigate tracking failures. 3) We propose a 4D Mask Fusion module, integrating memory-conditioned attention and logits equalization for robust embedding fusion. Extensive experiments demonstrate the effectiveness and flexibility of the proposed method on 4D human-centric parsing tasks, achieving up to 93.3% acceleration compared to the previous state-of-the-art method, which was limited to parsing fixed classes.

Qian Shao, Bang Du, Zepeng Li et al.

Clinical trials remain critical in cardiac drug development but face high failure rates due to efficacy limitations and safety risks, incurring substantial costs. In-silico trial methodologies, particularly generative models simulating drug-induced electrocardiogram (ECG) alterations, offer a potential solution to mitigate these challenges. While existing models show progress in ECG synthesis, their constrained fidelity and inability to characterize individual-specific pharmacological response patterns fundamentally limit clinical translatability. To address these issues, we propose a novel Drug-Aware Diffusion Model (DADM). Specifically, we construct a set of ordinary differential equations to provide external physical knowledge (EPK) of the realistic ECG morphology. The EPK is used to adaptively constrain the morphology of the generated ECGs through a dynamic cross-attention (DCA) mechanism. Furthermore, we propose an extension of ControlNet to incorporate demographic and drug data, simulating individual drug reactions. Compared to the other eight state-of-the-art (SOTA) ECG generative models: 1) Quantitative and expert evaluation demonstrate that DADM generates ECGs with superior fidelity; 2) Comparative results on two real-world databases covering 8 types of drug regimens verify that DADM can more accurately simulate drug-induced changes in ECGs, improving the accuracy by at least 5.79% and recall by 8%. In addition, the ECGs generated by DADM can also enhance model performance in downstream drug-effect classification tasks.

Qian Shao, Bang Du, Kai Zhang et al.

Deep learning models for pulmonary disease screening from Computed Tomography (CT) scans promise to alleviate the immense workload on radiologists. Still, their high computational cost, stemming from processing entire 3D volumes, remains a major barrier to widespread clinical adoption. Current sub-sampling techniques often compromise diagnostic integrity by introducing artifacts or discarding critical information. To overcome these limitations, we propose an Efficient and Reliable Framework (ERF) that fundamentally improves the practicality of automated CT analysis. Our framework introduces two core innovations: (1) A Cluster-based Sub-Sampling (CSS) method that efficiently selects a compact yet comprehensive subset of CT slices by optimizing for both representativeness and diversity. By integrating an efficient k-Nearest Neighbor (k-NN) search with an iterative refinement process, CSS bypasses the computational bottlenecks of previous methods while preserving vital diagnostic features. (2) A lightweight Hybrid Uncertainty Quantification (HUQ) mechanism, which uniquely assesses both Aleatoric Uncertainty (AU) and Epistemic Uncertainty (EU) with minimal computational overhead. By maximizing the discrepancy between auxiliary classifiers, HUQ provides a robust reliability score, which is crucial for building trust in automated systems operating on partial data. Validated on two public datasets with 2,654 CT volumes across diagnostic tasks for 3 pulmonary diseases, our proposed ERF achieves diagnostic performance comparable to the full-volume analysis (over 90% accuracy and recall) while reducing processing time by more than 60%. This work represents a significant step towards deploying fast, accurate, and trustworthy AI-powered screening tools in time-sensitive clinical settings.