Tassilo Klein

CV
h-index21
29papers
6,589citations
Novelty48%
AI Score55

29 Papers

CLMar 15, 2022
SCD: Self-Contrastive Decorrelation for Sentence Embeddings

Tassilo Klein, Moin Nabi

In this paper, we propose Self-Contrastive Decorrelation (SCD), a self-supervised approach. Given an input sentence, it optimizes a joint self-contrastive and decorrelation objective. Learning a representation is facilitated by leveraging the contrast arising from the instantiation of standard dropout at different rates. The proposed method is conceptually simple yet empirically powerful. It achieves comparable results with state-of-the-art methods on multiple benchmarks without using contrastive pairs. This study opens up avenues for efficient self-supervised learning methods that are more robust than current contrastive methods.

CLNov 9, 2022
miCSE: Mutual Information Contrastive Learning for Low-shot Sentence Embeddings

Tassilo Klein, Moin Nabi

This paper presents miCSE, a mutual information-based contrastive learning framework that significantly advances the state-of-the-art in few-shot sentence embedding. The proposed approach imposes alignment between the attention pattern of different views during contrastive learning. Learning sentence embeddings with miCSE entails enforcing the structural consistency across augmented views for every sentence, making contrastive self-supervised learning more sample efficient. As a result, the proposed approach shows strong performance in the few-shot learning domain. While it achieves superior results compared to state-of-the-art methods on multiple benchmarks in few-shot learning, it is comparable in the full-shot scenario. This study opens up avenues for efficient self-supervised learning methods that are more robust than current contrastive methods for sentence embedding.

LGApr 11, 2022
Mixture-of-experts VAEs can disregard variation in surjective multimodal data

Jannik Wolff, Tassilo Klein, Moin Nabi et al.

Machine learning systems are often deployed in domains that entail data from multiple modalities, for example, phenotypic and genotypic characteristics describe patients in healthcare. Previous works have developed multimodal variational autoencoders (VAEs) that generate several modalities. We consider subjective data, where single datapoints from one modality (such as class labels) describe multiple datapoints from another modality (such as images). We theoretically and empirically demonstrate that multimodal VAEs with a mixture of experts posterior can struggle to capture variability in such surjective data.

AIJan 12
SALT-KG: A Benchmark for Semantics-Aware Learning on Enterprise Tables

Isaiah Onando Mulang, Felix Sasaki, Tassilo Klein et al.

Building upon the SALT benchmark for relational prediction (Klein et al., 2024), we introduce SALT-KG, a benchmark for semantics-aware learning on enterprise tables. SALT-KG extends SALT by linking its multi-table transactional data with a structured Operational Business Knowledge represented in a Metadata Knowledge Graph (OBKG) that captures field-level descriptions, relational dependencies, and business object types. This extension enables evaluation of models that jointly reason over tabular evidence and contextual semantics, an increasingly critical capability for foundation models on structured data. Empirical analysis reveals that while metadata-derived features yield modest improvements in classical prediction metrics, these metadata features consistently highlight gaps in the ability of models to leverage semantics in relational context. By reframing tabular prediction as semantics-conditioned reasoning, SALT-KG establishes a benchmark to advance tabular foundation models grounded in declarative knowledge, providing the first empirical step toward semantically linked tables in structured data at enterprise scale.

79.4LGMay 10
Tabular Foundation Model for Generative Modelling

Xiangjian Jiang, Mingxuan Liu, Nikola Simidjievski et al.

Generative modelling is a demanding test of foundation models, because it requires robust, holistic representation learning for a given data modality, rather than optimisation for a supervised prediction target alone. While recent work on tabular foundation models has achieved remarkable progress in predictive modelling, generative tabular foundation models remain underexplored. Existing tabular foundation generators, in particular, have not yet consistently matched strong dataset-specific generators in synthetic data quality. A key reason is their misalignment with the distinctive causal structural prior of heterogeneous tabular data. In this paper, we address this gap by introducing a novel tabular foundation model, \textbf{TabFORGE}, built on pretrained \textbf{Tab}ular \textbf{FO}undational \textbf{R}epresentations for \textbf{GE}neration. TabFORGE is designed to utilise the implicitly learned causal information underlying diverse tabular datasets in a unified latent space induced by a pretrained causality-aware feature encoder. It further decouples latent modelling from decoding through a two-stage design: we first pretrain a score-based diffusion transformer, and then pretrain a denoising-aligned decoder using the denoised latent embeddings. This design elegantly mitigates the distribution shifts in latent embeddings that typically arise between training and inference. We evaluate TabFORGE comprehensively against 22 benchmark methods on 45 real-world datasets. Our results show that TabFORGE effectively learns and leverages generalisable tabular representations, enabling efficient generation of high-quality synthetic tabular data, particularly with strong structural fidelity.

GTFeb 24
The Headless Firm: How AI Reshapes Enterprise Boundaries

Tassilo Klein, Sebastian Wieczorek

The boundary of the firm is determined by coordination cost. We argue that agentic AI induces a structural change in how coordination costs scale: in prior modular systems, integration cost grew with interaction topology (O(n^2) in the number of components); in protocol-mediated agentic systems, integration cost collapses to O(n) while verification scales with task throughput rather than interaction count. This shift selects for a specific organizational equilibrium -- the Headless Firm -- structured as an hourglass: a personalized generative interface at the top, a standardized protocol waist in the middle, and a competitive market of micro-specialized execution agents at the bottom. We formalize this claim as a coordination cost model with two falsifiable empirical predictions: (1) the marginal cost of adding an execution provider should be approximately constant in a mature hourglass ecosystem; (2) the ratio of total coordination cost to task throughput should remain stable as ecosystem size grows. We derive conditions for hourglass stability versus re-centralization and analyze implications for firm size distributions, labor markets, and software economics. The analysis predicts a domain-conditional Great Unbundling: in high knowledge-velocity domains, firm size distributions shift mass from large integrated incumbents toward micro-specialized agents and thin protocol orchestrators.

LGOct 17, 2024
PORTAL: Scalable Tabular Foundation Models via Content-Specific Tokenization

Marco Spinaci, Marek Polewczyk, Johannes Hoffart et al.

Self-supervised learning on tabular data seeks to apply advances from natural language and image domains to the diverse domain of tables. However, current techniques often struggle with integrating multi-domain data and require data cleaning or specific structural requirements, limiting the scalability of pre-training datasets. We introduce PORTAL (Pretraining One-Row-at-a-Time for All tabLes), a framework that handles various data modalities without the need for cleaning or preprocessing. This simple yet powerful approach can be effectively pre-trained on online-collected datasets and fine-tuned to match state-of-the-art methods on complex classification and regression tasks. This work offers a practical advancement in self-supervised learning for large-scale tabular data.

LGJan 6, 2025
SALT: Sales Autocompletion Linked Business Tables Dataset

Tassilo Klein, Clemens Biehl, Margarida Costa et al.

Foundation models, particularly those that incorporate Transformer architectures, have demonstrated exceptional performance in domains such as natural language processing and image processing. Adapting these models to structured data, like tables, however, introduces significant challenges. These difficulties are even more pronounced when addressing multi-table data linked via foreign key, which is prevalent in the enterprise realm and crucial for empowering business use cases. Despite its substantial impact, research focusing on such linked business tables within enterprise settings remains a significantly important yet underexplored domain. To address this, we introduce a curated dataset sourced from an Enterprise Resource Planning (ERP) system, featuring extensive linked tables. This dataset is specifically designed to support research endeavors in table representation learning. By providing access to authentic enterprise data, our goal is to potentially enhance the effectiveness and applicability of models for real-world business contexts.

LGJul 14, 2025
Learning Private Representations through Entropy-based Adversarial Training

Tassilo Klein, Moin Nabi

How can we learn a representation with high predictive power while preserving user privacy? We present an adversarial representation learning method for sanitizing sensitive content from the learned representation. Specifically, we introduce a variant of entropy - focal entropy, which mitigates the potential information leakage of the existing entropy-based approaches. We showcase feasibility on multiple benchmarks. The results suggest high target utility at moderate privacy leakage.

CLJan 16, 2024
Contrastive Perplexity for Controlled Generation: An Application in Detoxifying Large Language Models

Tassilo Klein, Moin Nabi

The generation of toxic content by large language models (LLMs) remains a critical challenge for the safe deployment of language technology. We propose a novel framework for implicit knowledge editing and controlled text generation by fine-tuning LLMs with a prototype-based contrastive perplexity objective. Central to our method is the construction of hard negatives - toxic outputs that are generated through adversarial paraphrasing to be semantically similar and model probability to their non-toxic counterparts. By training on these challenging and realistic pairs, our approach ensures robust and stable contrastive optimization. Experimental results in the domain of detoxification demonstrate that our method significantly reduces toxic generation while maintaining strong performance on downstream tasks such as commonsense reasoning and reading comprehension. Our findings highlight the effectiveness of exploiting hard negatives for attribute-aware fine-tuning.

CLSep 10, 2021
Attention-based Contrastive Learning for Winograd Schemas

Tassilo Klein, Moin Nabi

Self-supervised learning has recently attracted considerable attention in the NLP community for its ability to learn discriminative features using a contrastive objective. This paper investigates whether contrastive learning can be extended to Transfomer attention to tackling the Winograd Schema Challenge. To this end, we propose a novel self-supervised framework, leveraging a contrastive loss directly at the level of self-attention. Experimental analysis of our attention-based models on multiple datasets demonstrates superior commonsense reasoning capabilities. The proposed approach outperforms all comparable unsupervised approaches while occasionally surpassing supervised ones.

CLSep 10, 2021
Towards Zero-shot Commonsense Reasoning with Self-supervised Refinement of Language Models

Tassilo Klein, Moin Nabi

Can we get existing language models and refine them for zero-shot commonsense reasoning? This paper presents an initial study exploring the feasibility of zero-shot commonsense reasoning for the Winograd Schema Challenge by formulating the task as self-supervised refinement of a pre-trained language model. In contrast to previous studies that rely on fine-tuning annotated datasets, we seek to boost conceptualization via loss landscape refinement. To this end, we propose a novel self-supervised learning approach that refines the language model utilizing a set of linguistic perturbations of similar concept relationships. Empirical analysis of our conceptually simple framework demonstrates the viability of zero-shot commonsense reasoning on multiple benchmarks.

CVNov 17, 2020
Multimodal Prototypical Networks for Few-shot Learning

Frederik Pahde, Mihai Puscas, Tassilo Klein et al.

Although providing exceptional results for many computer vision tasks, state-of-the-art deep learning algorithms catastrophically struggle in low data scenarios. However, if data in additional modalities exist (e.g. text) this can compensate for the lack of data and improve the classification results. To overcome this data scarcity, we design a cross-modal feature generation framework capable of enriching the low populated embedding space in few-shot scenarios, leveraging data from the auxiliary modality. Specifically, we train a generative model that maps text data into the visual feature space to obtain more reliable prototypes. This allows to exploit data from additional modalities (e.g. text) during training while the ultimate task at test time remains classification with exclusively visual data. We show that in such cases nearest neighbor classification is a viable approach and outperform state-of-the-art single-modal and multimodal few-shot learning methods on the CUB-200 and Oxford-102 datasets.

CVOct 22, 2020
Learning Graph-Based Priors for Generalized Zero-Shot Learning

Colin Samplawski, Jannik Wolff, Tassilo Klein et al.

The task of zero-shot learning (ZSL) requires correctly predicting the label of samples from classes which were unseen at training time. This is achieved by leveraging side information about class labels, such as label attributes or word embeddings. Recently, attention has shifted to the more realistic task of generalized ZSL (GZSL) where test sets consist of seen and unseen samples. Recent approaches to GZSL have shown the value of generative models, which are used to generate samples from unseen classes. In this work, we incorporate an additional source of side information in the form of a relation graph over labels. We leverage this graph in order to learn a set of prior distributions, which encourage an aligned variational autoencoder (VAE) model to learn embeddings which respect the graph structure. Using this approach we are able to achieve improved performance on the CUB and SUN benchmarks over a strong baseline.

CLMay 2, 2020
Contrastive Self-Supervised Learning for Commonsense Reasoning

Tassilo Klein, Moin Nabi

We propose a self-supervised method to solve Pronoun Disambiguation and Winograd Schema Challenge problems. Our approach exploits the characteristic structure of training corpora related to so-called "trigger" words, which are responsible for flipping the answer in pronoun disambiguation. We achieve such commonsense reasoning by constructing pair-wise contrastive auxiliary predictions. To this end, we leverage a mutual exclusive loss regularized by a contrastive margin. Our architecture is based on the recently introduced transformer networks, BERT, that exhibits strong performance on many NLP benchmarks. Empirical results show that our method alleviates the limitation of current supervised approaches for commonsense reasoning. This study opens up avenues for exploiting inexpensive self-supervision to achieve performance gain in commonsense reasoning tasks.

CVDec 11, 2019
Multimodal Self-Supervised Learning for Medical Image Analysis

Aiham Taleb, Christoph Lippert, Tassilo Klein et al.

Self-supervised learning approaches leverage unlabeled samples to acquire generic knowledge about different concepts, hence allowing for annotation-efficient downstream task learning. In this paper, we propose a novel self-supervised method that leverages multiple imaging modalities. We introduce the multimodal puzzle task, which facilitates rich representation learning from multiple image modalities. The learned representations allow for subsequent fine-tuning on different downstream tasks. To achieve that, we learn a modality-agnostic feature embedding by confusing image modalities at the data-level. Together with the Sinkhorn operator, with which we formulate the puzzle solving optimization as permutation matrix inference instead of classification, they allow for efficient solving of multimodal puzzles with varying levels of complexity. In addition, we also propose to utilize cross-modal generation techniques for multimodal data augmentation used for training self-supervised tasks. In other words, we exploit synthetic images for self-supervised pretraining, instead of downstream tasks directly, in order to circumvent quality issues associated with synthetic images, while improving data-efficiency and representations quality. Our experimental results, which assess the gains in downstream performance and data-efficiency, show that solving our multimodal puzzles yields better semantic representations, compared to treating each modality independently. Our results also highlight the benefits of exploiting synthetic images for self-supervised pretraining. We showcase our approach on four downstream tasks: Brain tumor segmentation and survival days prediction using four MRI modalities, Prostate segmentation using two MRI modalities, and Liver segmentation using unregistered CT and MRI modalities. We outperform many previous solutions, and achieve results competitive to state-of-the-art.

CVNov 30, 2019
Pruning at a Glance: Global Neural Pruning for Model Compression

Abdullah Salama, Oleksiy Ostapenko, Tassilo Klein et al.

Deep Learning models have become the dominant approach in several areas due to their high performance. Unfortunately, the size and hence computational requirements of operating such models can be considerably high. Therefore, this constitutes a limitation for deployment on memory and battery constrained devices such as mobile phones or embedded systems. To address these limitations, we propose a novel and simple pruning method that compresses neural networks by removing entire filters and neurons according to a global threshold across the network without any pre-calculation of layer sensitivity. The resulting model is compact, non-sparse, with the same accuracy as the non-compressed model, and most importantly requires no special infrastructure for deployment. We prove the viability of our method by producing highly compressed models, namely VGG-16, ResNet-56, and ResNet-110 respectively on CIFAR10 without losing any performance compared to the baseline, as well as ResNet-34 and ResNet-50 on ImageNet without a significant loss of accuracy. We also provide a well-retrained 30% compressed ResNet-50 that slightly surpasses the base model accuracy. Additionally, compressing more than 56% and 97% of AlexNet and LeNet-5 respectively. Interestingly, the resulted models' pruning patterns are highly similar to the other methods using layer sensitivity pre-calculation step. Our method does not only exhibit good performance but what is more also easy to implement.

CLNov 6, 2019
Learning to Answer by Learning to Ask: Getting the Best of GPT-2 and BERT Worlds

Tassilo Klein, Moin Nabi

Automatic question generation aims at the generation of questions from a context, with the corresponding answers being sub-spans of the given passage. Whereas, most of the methods mostly rely on heuristic rules to generate questions, more recently also neural network approaches have been proposed. In this work, we propose a variant of the self-attention Transformer network architectures model to generate meaningful and diverse questions. To this end, we propose an easy to use model consisting of the conjunction of the Transformer decoder GPT-2 model with Transformer encoder BERT for the downstream task for question answering. The model is trained in an end-to-end fashion, where the language model is trained to produce a question-answer-aware input representation that facilitates to generate an answer focused question. Our result of neural question generation from text on the SQuAD 1.1 dataset suggests that our method can produce semantically correct and diverse questions. Additionally, we assessed the performance of our proposed method for the downstream task of question answering. The analysis shows that our proposed generation & answering collaboration framework relatively improves both tasks and is particularly powerful in the semi-supervised setup. The results further suggest a robust and comparably lean pipeline facilitating question generation in the small-data regime.

CLMay 31, 2019
Attention Is (not) All You Need for Commonsense Reasoning

Tassilo Klein, Moin Nabi

The recently introduced BERT model exhibits strong performance on several language understanding benchmarks. In this paper, we describe a simple re-implementation of BERT for commonsense reasoning. We show that the attentions produced by BERT can be directly utilized for tasks such as the Pronoun Disambiguation Problem and Winograd Schema Challenge. Our proposed attention-guided commonsense reasoning method is conceptually simple yet empirically powerful. Experimental analysis on multiple datasets demonstrates that our proposed system performs remarkably well on all cases while outperforming the previously reported state of the art by a margin. While results suggest that BERT seems to implicitly learn to establish complex relationships between entities, solving commonsense reasoning tasks might require more than unsupervised models learned from huge text corpora.

CVMay 15, 2019
Budget-Aware Adapters for Multi-Domain Learning

Rodrigo Berriel, Stéphane Lathuilière, Moin Nabi et al.

Multi-Domain Learning (MDL) refers to the problem of learning a set of models derived from a common deep architecture, each one specialized to perform a task in a certain domain (e.g., photos, sketches, paintings). This paper tackles MDL with a particular interest in obtaining domain-specific models with an adjustable budget in terms of the number of network parameters and computational complexity. Our intuition is that, as in real applications the number of domains and tasks can be very large, an effective MDL approach should not only focus on accuracy but also on having as few parameters as possible. To implement this idea we derive specialized deep models for each domain by adapting a pre-trained architecture but, differently from other methods, we propose a novel strategy to automatically adjust the computational complexity of the network. To this aim, we introduce Budget-Aware Adapters that select the most relevant feature channels to better handle data from a novel domain. Some constraints on the number of active switches are imposed in order to obtain a network respecting the desired complexity budget. Experimentally, we show that our approach leads to recognition accuracy competitive with state-of-the-art approaches but with much lighter networks both in terms of storage and computation.

NEApr 5, 2019
Learning to Remember: A Synaptic Plasticity Driven Framework for Continual Learning

Oleksiy Ostapenko, Mihai Puscas, Tassilo Klein et al.

Models trained in the context of continual learning (CL) should be able to learn from a stream of data over an undefined period of time. The main challenges herein are: 1) maintaining old knowledge while simultaneously benefiting from it when learning new tasks, and 2) guaranteeing model scalability with a growing amount of data to learn from. In order to tackle these challenges, we introduce Dynamic Generative Memory (DGM) - a synaptic plasticity driven framework for continual learning. DGM relies on conditional generative adversarial networks with learnable connection plasticity realized with neural masking. Specifically, we evaluate two variants of neural masking: applied to (i) layer activations and (ii) to connection weights directly. Furthermore, we propose a dynamic network expansion mechanism that ensures sufficient model capacity to accommodate for continually incoming tasks. The amount of added capacity is determined dynamically from the learned binary mask. We evaluate DGM in the continual class-incremental setup on visual classification tasks.

CVJan 4, 2019
Low-Shot Learning from Imaginary 3D Model

Frederik Pahde, Mihai Puscas, Jannik Wolff et al.

Since the advent of deep learning, neural networks have demonstrated remarkable results in many visual recognition tasks, constantly pushing the limits. However, the state-of-the-art approaches are largely unsuitable in scarce data regimes. To address this shortcoming, this paper proposes employing a 3D model, which is derived from training images. Such a model can then be used to hallucinate novel viewpoints and poses for the scarce samples of the few-shot learning scenario. A self-paced learning approach allows for the selection of a diverse set of high-quality images, which facilitates the training of a classifier. The performance of the proposed approach is showcased on the fine-grained CUB-200-2011 dataset in a few-shot setting and significantly improves our baseline accuracy.

CVNov 22, 2018
Self Paced Adversarial Training for Multimodal Few-shot Learning

Frederik Pahde, Oleksiy Ostapenko, Patrick Jähnichen et al.

State-of-the-art deep learning algorithms yield remarkable results in many visual recognition tasks. However, they still fail to provide satisfactory results in scarce data regimes. To a certain extent this lack of data can be compensated by multimodal information. Missing information in one modality of a single data point (e.g. an image) can be made up for in another modality (e.g. a textual description). Therefore, we design a few-shot learning task that is multimodal during training (i.e. image and text) and single-modal during test time (i.e. image). In this regard, we propose a self-paced class-discriminative generative adversarial network incorporating multimodality in the context of few-shot learning. The proposed approach builds upon the idea of cross-modal data generation in order to alleviate the data sparsity problem. We improve few-shot learning accuracies on the finegrained CUB and Oxford-102 datasets.

CVSep 12, 2018
The Wisdom of MaSSeS: Majority, Subjectivity, and Semantic Similarity in the Evaluation of VQA

Shailza Jolly, Sandro Pezzelle, Tassilo Klein et al.

We introduce MASSES, a simple evaluation metric for the task of Visual Question Answering (VQA). In its standard form, the VQA task is operationalized as follows: Given an image and an open-ended question in natural language, systems are required to provide a suitable answer. Currently, model performance is evaluated by means of a somehow simplistic metric: If the predicted answer is chosen by at least 3 human annotators out of 10, then it is 100% correct. Though intuitively valuable, this metric has some important limitations. First, it ignores whether the predicted answer is the one selected by the Majority (MA) of annotators. Second, it does not account for the quantitative Subjectivity (S) of the answers in the sample (and dataset). Third, information about the Semantic Similarity (SES) of the responses is completely neglected. Based on such limitations, we propose a multi-component metric that accounts for all these issues. We show that our metric is effective in providing a more fine-grained evaluation both on the quantitative and qualitative level.

CVJun 13, 2018
Cross-modal Hallucination for Few-shot Fine-grained Recognition

Frederik Pahde, Patrick Jähnichen, Tassilo Klein et al.

State-of-the-art deep learning algorithms generally require large amounts of data for model training. Lack thereof can severely deteriorate the performance, particularly in scenarios with fine-grained boundaries between categories. To this end, we propose a multimodal approach that facilitates bridging the information gap by means of meaningful joint embeddings. Specifically, we present a benchmark that is multimodal during training (i.e. images and texts) and single-modal in testing time (i.e. images), with the associated task to utilize multimodal data in base classes (with many samples), to learn explicit visual classifiers for novel classes (with few samples). Next, we propose a framework built upon the idea of cross-modal data hallucination. In this regard, we introduce a discriminative text-conditional GAN for sample generation with a simple self-paced strategy for sample selection. We show the results of our proposed discriminative hallucinated method for 1-, 2-, and 5- shot learning on the CUB dataset, where the accuracy is improved by employing multimodal data.

CVApr 4, 2018
Gaussian Process Uncertainty in Age Estimation as a Measure of Brain Abnormality

Benjamin Gutierrez Becker, Tassilo Klein, Christian Wachinger

Multivariate regression models for age estimation are a powerful tool for assessing abnormal brain morphology associated to neuropathology. Age prediction models are built on cohorts of healthy subjects and are built to reflect normal aging patterns. The application of these multivariate models to diseased subjects usually results in high prediction errors, under the hypothesis that neuropathology presents a similar degenerative pattern as that of accelerated aging. In this work, we propose an alternative to the idea that pathology follows a similar trajectory than normal aging. Instead, we propose the use of metrics which measure deviations from the mean aging trajectory. We propose to measure these deviations using two different metrics: uncertainty in a Gaussian process regression model and a newly proposed age weighted uncertainty measure. Consequently, our approach assumes that pathologic brain patterns are different to those of normal aging. We present results for subjects with autism, mild cognitive impairment and Alzheimer's disease to highlight the versatility of the approach to different diseases and age ranges. We evaluate volume, thickness, and VBM features for quantifying brain morphology. Our evaluations are performed on a large number of images obtained from a variety of publicly available neuroimaging databases. Across all features, our uncertainty based measurements yield a better separation between diseased subjects and healthy individuals than the prediction error. Finally, we illustrate differences in the disease pattern to normal aging, supporting the application of uncertainty as a measure of neuropathology.

CRDec 20, 2017
Differentially Private Federated Learning: A Client Level Perspective

Robin C. Geyer, Tassilo Klein, Moin Nabi

Federated learning is a recent advance in privacy protection. In this context, a trusted curator aggregates parameters optimized in decentralized fashion by multiple clients. The resulting model is then distributed back to all clients, ultimately converging to a joint representative model without explicitly having to share the data. However, the protocol is vulnerable to differential attacks, which could originate from any party contributing during federated optimization. In such an attack, a client's contribution during training and information about their data set is revealed through analyzing the distributed model. We tackle this problem and propose an algorithm for client sided differential privacy preserving federated optimization. The aim is to hide clients' contributions during training, balancing the trade-off between privacy loss and model performance. Empirical studies suggest that given a sufficiently large number of participating clients, our proposed procedure can maintain client-level differential privacy at only a minor cost in model performance.

CVMay 23, 2017
A Multi-Armed Bandit to Smartly Select a Training Set from Big Medical Data

Benjamín Gutiérrez, Loïc Peter, Tassilo Klein et al.

With the availability of big medical image data, the selection of an adequate training set is becoming more important to address the heterogeneity of different datasets. Simply including all the data does not only incur high processing costs but can even harm the prediction. We formulate the smart and efficient selection of a training dataset from big medical image data as a multi-armed bandit problem, solved by Thompson sampling. Our method assumes that image features are not available at the time of the selection of the samples, and therefore relies only on meta information associated with the images. Our strategy simultaneously exploits data sources with high chances of yielding useful samples and explores new data regions. For our evaluation, we focus on the application of estimating the age from a brain MRI. Our results on 7,250 subjects from 10 datasets show that our approach leads to higher accuracy while only requiring a fraction of the training data.

CVFeb 27, 2017
DeepNAT: Deep Convolutional Neural Network for Segmenting Neuroanatomy

Christian Wachinger, Martin Reuter, Tassilo Klein

We introduce DeepNAT, a 3D Deep convolutional neural network for the automatic segmentation of NeuroAnaTomy in T1-weighted magnetic resonance images. DeepNAT is an end-to-end learning-based approach to brain segmentation that jointly learns an abstract feature representation and a multi-class classification. We propose a 3D patch-based approach, where we do not only predict the center voxel of the patch but also neighbors, which is formulated as multi-task learning. To address a class imbalance problem, we arrange two networks hierarchically, where the first one separates foreground from background, and the second one identifies 25 brain structures on the foreground. Since patches lack spatial context, we augment them with coordinates. To this end, we introduce a novel intrinsic parameterization of the brain volume, formed by eigenfunctions of the Laplace-Beltrami operator. As network architecture, we use three convolutional layers with pooling, batch normalization, and non-linearities, followed by fully connected layers with dropout. The final segmentation is inferred from the probabilistic output of the network with a 3D fully connected conditional random field, which ensures label agreement between close voxels. The roughly 2.7 million parameters in the network are learned with stochastic gradient descent. Our results show that DeepNAT compares favorably to state-of-the-art methods. Finally, the purely learning-based method may have a high potential for the adaptation to young, old, or diseased brains by fine-tuning the pre-trained network with a small training sample on the target application, where the availability of larger datasets with manual annotations may boost the overall segmentation accuracy in the future.