Lu Cheng

Xiaofan Zhou, Zisu Wang, Janice Krieger et al.

Clinical trials (CT) are essential for advancing medical research and treatment, yet efficiently recruiting eligible participants -- each of whom must meet complex eligibility criteria -- remains a significant challenge. Traditional recruitment approaches, such as advertisements or electronic health record screening within hospitals, are often time-consuming and geographically constrained. This work addresses the recruitment challenge by leveraging the vast amount of health-related information individuals share on social media platforms. With the emergence of powerful large language models (LLMs) capable of sophisticated text understanding, we pose the central research question: Can LLM-driven tools facilitate CT recruitment by identifying potential participants through their engagement on social media? To investigate this question, we introduce TRIALQA, a novel dataset comprising two social media collections from the subreddits on colon cancer and prostate cancer. Using eligibility criteria from public real-world CTs, experienced annotators are hired to annotate TRIALQA to indicate (1) whether a social media user meets a given eligibility criterion and (2) the user's stated reasons for interest in participating in CT. We benchmark seven widely used LLMs on these two prediction tasks, employing six distinct training and inference strategies. Our extensive experiments reveal that, while LLMs show considerable promise, they still face challenges in performing the complex, multi-hop reasoning needed to accurately assess eligibility criteria.

Zihao Li, Ruixiang Tang, Lu Cheng et al.

Pre-trained language models (PLMs) have achieved impressive results on various natural language processing tasks. However, recent research has revealed that these models often rely on superficial features and shortcuts instead of developing a genuine understanding of language, especially for natural language understanding (NLU) tasks. Consequently, the models struggle to generalize to out-of-domain data. In this work, we propose Divergence Based Regularization (DBR) to mitigate this shortcut learning behavior. Our method measures the divergence between the output distributions for original examples and examples where shortcut tokens have been masked. This process prevents the model's predictions from being overly influenced by shortcut features or biases. We evaluate our model on three NLU tasks and find that it improves out-of-domain performance with little loss of in-domain accuracy. Our results demonstrate that reducing the reliance on shortcuts and superficial features can enhance the generalization ability of large pre-trained language models.

Anique Tahir, Lu Cheng, Manuel Sandoval et al.

Social media discourse involves people from different backgrounds, beliefs, and motives. Thus, often such discourse can devolve into toxic interactions. Generative Models, such as Llama and ChatGPT, have recently exploded in popularity due to their capabilities in zero-shot question-answering. Because these models are increasingly being used to ask questions of social significance, a crucial research question is whether they can understand social media dynamics. This work provides a critical analysis regarding generative LLM's ability to understand language and dynamics in social contexts, particularly considering cyberbullying and anti-cyberbullying (posts aimed at reducing cyberbullying) interactions. Specifically, we compare and contrast the capabilities of different large language models (LLMs) to understand three key aspects of social dynamics: language, directionality, and the occurrence of bullying/anti-bullying messages. We found that while fine-tuned LLMs exhibit promising results in some social media understanding tasks (understanding directionality), they presented mixed results in others (proper paraphrasing and bullying/anti-bullying detection). We also found that fine-tuning and prompt engineering mechanisms can have positive effects in some tasks. We believe that a understanding of LLM's capabilities is crucial to design future models that can be effectively used in social applications.

Chengyuan Deng, Yiqun Duan, Xin Jin et al.

Large Language Models (LLMs) have achieved unparalleled success across diverse language modeling tasks in recent years. However, this progress has also intensified ethical concerns, impacting the deployment of LLMs in everyday contexts. This paper provides a comprehensive survey of ethical challenges associated with LLMs, from longstanding issues such as copyright infringement, systematic bias, and data privacy, to emerging problems like truthfulness and social norms. We critically analyze existing research aimed at understanding, examining, and mitigating these ethical risks. Our survey underscores integrating ethical standards and societal values into the development of LLMs, thereby guiding the development of responsible and ethically aligned language models.

Zihan Chen, Lei Nico Zheng, Cheng Lu et al.

ChatGPT has demonstrated remarkable capabilities across various natural language processing (NLP) tasks. However, its potential for inferring dynamic network structures from temporal textual data, specifically financial news, remains an unexplored frontier. In this research, we introduce a novel framework that leverages ChatGPT's graph inference capabilities to enhance Graph Neural Networks (GNN). Our framework adeptly extracts evolving network structures from textual data, and incorporates these networks into graph neural networks for subsequent predictive tasks. The experimental results from stock movement forecasting indicate our model has consistently outperformed the state-of-the-art Deep Learning-based benchmarks. Furthermore, the portfolios constructed based on our model's outputs demonstrate higher annualized cumulative returns, alongside reduced volatility and maximum drawdown. This superior performance highlights the potential of ChatGPT for text-based network inferences and underscores its promising implications for the financial sector.

Lu Cheng, Ruocheng Guo, Kasim Selcuk Candan et al.

Online review systems are the primary means through which many businesses seek to build the brand and spread their messages. Prior research studying the effects of online reviews has been mainly focused on a single numerical cause, e.g., ratings or sentiment scores. We argue that such notions of causes entail three key limitations: they solely consider the effects of single numerical causes and ignore different effects of multiple aspects -- e.g., Food, Service -- embedded in the textual reviews; they assume the absence of hidden confounders in observational studies, e.g., consumers' personal preferences; and they overlook the indirect effects of numerical causes that can potentially cancel out the effect of textual reviews on business revenue. We thereby propose an alternative perspective to this single-cause-based effect estimation of online reviews: in the presence of hidden confounders, we consider multi-aspect textual reviews, particularly, their total effects on business revenue and direct effects with the numerical cause -- ratings -- being the mediator. We draw on recent advances in machine learning and causal inference to together estimate the hidden confounders and causal effects. We present empirical evaluations using real-world examples to discuss the importance and implications of differentiating the multi-aspect effects in strategizing business operations.

Lu Cheng, Ahmadreza Mosallanezhad, Paras Sheth et al.

There have been increasing concerns about Artificial Intelligence (AI) due to its unfathomable potential power. To make AI address ethical challenges and shun undesirable outcomes, researchers proposed to develop socially responsible AI (SRAI). One of these approaches is causal learning (CL). We survey state-of-the-art methods of CL for SRAI. We begin by examining the seven CL tools to enhance the social responsibility of AI, then review how existing works have succeeded using these tools to tackle issues in developing SRAI such as fairness. The goal of this survey is to bring forefront the potentials and promises of CL for SRAI.

Lu Cheng, Ruocheng Guo, Huan Liu

An important problem in causal inference is to break down the total effect of a treatment on an outcome into different causal pathways and to quantify the causal effect in each pathway. For instance, in causal fairness, the total effect of being a male employee (i.e., treatment) constitutes its direct effect on annual income (i.e., outcome) and the indirect effect via the employee's occupation (i.e., mediator). Causal mediation analysis (CMA) is a formal statistical framework commonly used to reveal such underlying causal mechanisms. One major challenge of CMA in observational studies is handling confounders, variables that cause spurious causal relationships among treatment, mediator, and outcome. Conventional methods assume sequential ignorability that implies all confounders can be measured, which is often unverifiable in practice. This work aims to circumvent the stringent sequential ignorability assumptions and consider hidden confounders. Drawing upon proxy strategies and recent advances in deep learning, we propose to simultaneously uncover the latent variables that characterize hidden confounders and estimate the causal effects. Empirical evaluations using both synthetic and semi-synthetic datasets validate the effectiveness of the proposed method. We further show the potentials of our approach for causal fairness analysis.

Lu Cheng, Kush R. Varshney, Huan Liu

In the current era, people and society have grown increasingly reliant on artificial intelligence (AI) technologies. AI has the potential to drive us towards a future in which all of humanity flourishes. It also comes with substantial risks for oppression and calamity. Discussions about whether we should (re)trust AI have repeatedly emerged in recent years and in many quarters, including industry, academia, healthcare, services, and so on. Technologists and AI researchers have a responsibility to develop trustworthy AI systems. They have responded with great effort to design more responsible AI algorithms. However, existing technical solutions are narrow in scope and have been primarily directed towards algorithms for scoring or classification tasks, with an emphasis on fairness and unwanted bias. To build long-lasting trust between AI and human beings, we argue that the key is to think beyond algorithmic fairness and connect major aspects of AI that potentially cause AI's indifferent behavior. In this survey, we provide a systematic framework of Socially Responsible AI Algorithms that aims to examine the subjects of AI indifference and the need for socially responsible AI algorithms, define the objectives, and introduce the means by which we may achieve these objectives. We further discuss how to leverage this framework to improve societal well-being through protection, information, and prevention/mitigation.

Suyu Ge, Lu Cheng, Huan Liu

Cyberbullying, identified as intended and repeated online bullying behavior, has become increasingly prevalent in the past few decades. Despite the significant progress made thus far, the focus of most existing work on cyberbullying detection lies in the independent content analysis of different comments within a social media session. We argue that such leading notions of analysis suffer from three key limitations: they overlook the temporal correlations among different comments; they only consider the content within a single comment rather than the topic coherence across comments; they remain generic and exploit limited interactions between social media users. In this work, we observe that user comments in the same session may be inherently related, e.g., discussing similar topics, and their interaction may evolve over time. We also show that modeling such topic coherence and temporal interaction are critical to capture the repetitive characteristics of bullying behavior, thus leading to better predicting performance. To achieve the goal, we first construct a unified temporal graph for each social media session. Drawing on recent advances in graph neural network, we then propose a principled graph-based approach for modeling the temporal dynamics and topic coherence throughout user interactions. We empirically evaluate the effectiveness of our approach with the tasks of session-level bullying detection and comment-level case study. Our code is released to public.

Lu Cheng, Ruocheng Guo, Huan Liu

There are many scenarios where short- and long-term causal effects of an intervention are different. For example, low-quality ads may increase short-term ad clicks but decrease the long-term revenue via reduced clicks. This work, therefore, studies the problem of long-term effect where the outcome of primary interest, or primary outcome, takes months or even years to accumulate. The observational study of long-term effect presents unique challenges. First, the confounding bias causes large estimation error and variance, which can further accumulate towards the prediction of primary outcomes. Second, short-term outcomes are often directly used as the proxy of the primary outcome, i.e., the surrogate. Nevertheless, this method entails the strong surrogacy assumption that is often impractical. To tackle these challenges, we propose to build connections between long-term causal inference and sequential models in machine learning. This enables us to learn surrogate representations that account for the temporal unconfoundedness and circumvent the stringent surrogacy assumption by conditioning on the inferred time-varying confounders. Experimental results show that the proposed framework outperforms the state-of-the-art.

Ruocheng Guo, Lu Cheng, Jundong Li et al.

This work considers the question of how convenient access to copious data impacts our ability to learn causal effects and relations. In what ways is learning causality in the era of big data different from -- or the same as -- the traditional one? To answer this question, this survey provides a comprehensive and structured review of both traditional and frontier methods in learning causality and relations along with the connections between causality and machine learning. This work points out on a case-by-case basis how big data facilitates, complicates, or motivates each approach.