Stephen V. Faraone

Hakan T. Otal, Stephen V. Faraone, M. Abdullah Canbaz

Attention-Deficit/Hyperactivity Disorder (ADHD) is a challenging disorder to study due to its complex symptomatology and diverse contributing factors. To explore how we can gain deeper insights on this topic, we performed a network analysis on a comprehensive knowledge graph (KG) of ADHD, constructed by integrating scientific literature and clinical data with the help of cutting-edge large language models. The analysis, including k-core techniques, identified critical nodes and relationships that are central to understanding the disorder. Building on these findings, we curated a knowledge graph that is usable in a context-aware chatbot (Graph-RAG) with Large Language Models (LLMs), enabling accurate and informed interactions. Our knowledge graph not only advances the understanding of ADHD but also provides a powerful tool for research and clinical applications.

Fatih Altay, Guillermo Ramon Sanchez, Yanli James et al.

Alzheimer's disease is one of the diseases that mostly affects older people without being a part of aging. The most common symptoms include problems with communicating and abstract thinking, as well as disorientation. It is important to detect Alzheimer's disease in early stages so that cognitive functioning would be improved by medication and training. In this paper, we propose two attention model networks for detecting Alzheimer's disease from MRI images to help early detection efforts at the preclinical stage. We also compare the performance of these two attention network models with a baseline model. Recently available OASIS-3 Longitudinal Neuroimaging, Clinical, and Cognitive Dataset is used to train, evaluate and compare our models. The novelty of this research resides in the fact that we aim to detect Alzheimer's disease when all the parameters, physical assessments, and clinical data state that the patient is healthy and showing no symptoms