Xiaopeng Si

Yulin Sun, Xiaopeng Si, Runnan He et al.

Timely identification of harmful brain activities via electroencephalography (EEG) is critical for brain disease diagnosis and treatment, which remains limited application due to inter-rater variability, resource constraints, and poor generalizability of existing artificial intelligence (AI) models. In this study, a convolutional neural network model, VIPEEGNet, was developed and validated using EEGs recorded from Massachusetts General Hospital/Harvard Medical School. The VIPEEGNet was developed and validated using two independent datasets, collected between 2006 and 2020. The development cohort included EEG recordings from 1950 patients, with 106,800 EEG segments annotated by at least one experts (ranging from 1 to 28). The online testing cohort consisted of EEG segments from a subset of an additional 1,532 patients, each annotated by at least 10 experts. For the development cohort (n=1950), the VIPEEGNet achieved high accuracy, with an AUROC for binary classification of seizure, LPD, GPD, LRDA, GRDA, and "other" categories at 0.972 (95% CI, 0.957-0.988), 0.962 (95% CI, 0.954-0.970), 0.972 (95% CI, 0.960-0.984), 0.938 (95% CI, 0.917-0.959), 0.949 (95% CI, 0.941-0.957), and 0.930 (95% CI, 0.926-0.935). For multi classification, the sensitivity of VIPEEGNET for the six categories ranges from 36.8% to 88.2% and the precision ranges from 55.6% to 80.4%, and performance similar to human experts. Notably, the external validation showed Kullback-Leibler Divergence (KLD)of 0.223 and 0.273, ranking top 2 among the existing 2,767 competing algorithms, while we only used 2.8% of the parameters of the first-ranked algorithm.

Xiaopeng Si, Dong Huang, Yulin Sun et al.

Emotion recognition plays a crucial role in human-computer interaction, and electroencephalography (EEG) is advantageous for reflecting human emotional states. In this study, we propose MACTN, a hierarchical hybrid model for jointly modeling local and global temporal information. The model is inspired by neuroscience research on the temporal dynamics of emotions. MACTN extracts local emotional features through a convolutional neural network (CNN) and integrates sparse global emotional features through a transformer. Moreover, we employ channel attention mechanisms to identify the most task-relevant channels. Through extensive experimentation on two publicly available datasets, namely THU-EP and DEAP, our proposed method, MACTN, consistently achieves superior classification accuracy and F1 scores compared to other existing methods in most experimental settings. Furthermore, ablation studies have shown that the integration of both self-attention mechanisms and channel attention mechanisms leads to improved classification performance. Finally, an earlier version of this method, which shares the same ideas, won the Emotional BCI Competition's final championship in the 2022 World Robot Contest.