Issa Traoré

William Briguglio, Parisa Moghaddam, Waleed A. Yousef et al.

Precision medicine is an emerging approach for disease treatment and prevention that delivers personalized care to individual patients by considering their genetic makeups, medical histories, environments, and lifestyles. Despite the rapid advancement of precision medicine and its considerable promise, several underlying technological challenges remain unsolved. One such challenge of great importance is the security and privacy of precision health-related data, such as genomic data and electronic health records, which stifle collaboration and hamper the full potential of machine-learning (ML) algorithms. To preserve data privacy while providing ML solutions, this article makes three contributions. First, we propose a generic machine learning with encryption (MLE) framework, which we used to build an ML model that predicts cancer from one of the most recent comprehensive genomics datasets in the field. Second, our framework's prediction accuracy is slightly higher than that of the most recent studies conducted on the same dataset, yet it maintains the privacy of the patients' genomic data. Third, to facilitate the validation, reproduction, and extension of this work, we provide an open-source repository that contains the design and implementation of the framework, all the ML experiments and code, and the final predictive model deployed to a free cloud service.

Andrew Naguib, Waleed A. Yousef, Issa Traoré et al.

Recently, machine learning of the branch and bound algorithm has shown promise in approximating competent solutions to NP-hard problems. In this paper, we utilize and comprehensively compare the outcomes of three neural networks--graph convolutional neural network (GCNN), GraphSAGE, and graph attention network (GAT)--to solve the capacitated vehicle routing problem. We train these neural networks to emulate the decision-making process of the computationally expensive Strong Branching strategy. The neural networks are trained on six instances with distinct topologies from the CVRPLIB and evaluated on eight additional instances. Moreover, we reduced the minimum number of vehicles required to solve a CVRP instance to a bin-packing problem, which was addressed in a similar manner. Through rigorous experimentation, we found that this approach can match or improve upon the performance of the branch and bound algorithm with the Strong Branching strategy while requiring significantly less computational time. The source code that corresponds to our research findings and methodology is readily accessible and available for reference at the following web address: https://isotlaboratory.github.io/ml4vrp

Shiv Sondhi, Sherif Saad, Kevin Shi et al.

A critical component of any blockchain or distributed ledger technology (DLT) platform is the consensus algorithm. Blockchain consensus algorithms are the primary vehicle for the nodes within a blockchain network to reach an agreement. In recent years, many blockchain consensus algorithms have been proposed mainly for private and permissioned blockchain networks. However, the performance of these algorithms and their reliability in hostile environments or the presence of byzantine and other network failures are not well understood. In addition, the testing and validation of blockchain applications come with many technical challenges. In this paper, we apply chaos engineering and testing to understand the performance of consensus algorithms in the presence of different loads, byzantine failure and other communication failure scenarios. We apply chaos engineering to evaluate the performance of three different consensus algorithms (PBFT, Clique, Raft) and their respective blockchain platforms. We measure the blockchain network's throughput, latency, and success rate while executing chaos and load tests. We develop lightweight blockchain applications to execute our test in a semi-production environment. Our results show that using chaos engineering helps understand how different consensus algorithms perform in a hostile or unreliable environment and the limitations of blockchain platforms. Our work demonstrates the benefits of using chaos engineering in testing complex distributed systems such as blockchain networks.

Waleed A. Yousef, Issa Traore, William Briguglio

This paper explores the calibration of a classifier output score in binary classification problems. A calibrator is a function that maps the arbitrary classifier score, of a testing observation, onto $[0,1]$ to provide an estimate for the posterior probability of belonging to one of the two classes. Calibration is important for two reasons; first, it provides a meaningful score, that is the posterior probability; second, it puts the scores of different classifiers on the same scale for comparable interpretation. The paper presents three main contributions: (1) Introducing multi-score calibration, when more than one classifier provides a score for a single observation. (2) Introducing the idea that the classifier scores to a calibration process are nothing but features to a classifier, hence proposing expanding the classifier scores to higher dimensions to boost the calibrator's performance. (3) Conducting a massive simulation study, in the order of 24,000 experiments, that incorporates different configurations, in addition to experimenting on two real datasets from the cybersecurity domain. The results show that there is no overall winner among the different calibrators and different configurations. However, general advices for practitioners include the following: the Platt's calibrator~\citep{Platt1999ProbabilisticOutputsForSupport}, a version of the logistic regression that decreases bias for a small sample size, has a very stable and acceptable performance among all experiments; our suggested multi-score calibration provides better performance than single score calibration in the majority of experiments, including the two real datasets. In addition, expanding the scores can help in some experiments.