Yu Huang

Yu Huang, Zelin Peng, Yichen Zhao et al.

Medical image segmentation is crucial for clinical diagnosis, yet existing models are limited by their reliance on explicit human instructions and lack the active reasoning capabilities to understand complex clinical questions. While recent advancements in multimodal large language models (MLLMs) have improved medical question-answering (QA) tasks, most methods struggle to generate precise segmentation masks, limiting their application in automatic medical diagnosis. In this paper, we introduce medical image reasoning segmentation, a novel task that aims to generate segmentation masks based on complex and implicit medical instructions. To address this, we propose MedSeg-R, an end-to-end framework that leverages the reasoning abilities of MLLMs to interpret clinical questions while also capable of producing corresponding precise segmentation masks for medical images. It is built on two core components: 1) a global context understanding module that interprets images and comprehends complex medical instructions to generate multi-modal intermediate tokens, and 2) a pixel-level grounding module that decodes these tokens to produce precise segmentation masks and textual responses. Furthermore, we introduce MedSeg-QA, a large-scale dataset tailored for the medical image reasoning segmentation task. It includes over 10,000 image-mask pairs and multi-turn conversations, automatically annotated using large language models and refined through physician reviews. Experiments show MedSeg-R's superior performance across several benchmarks, achieving high segmentation accuracy and enabling interpretable textual analysis of medical images.

Yu Huang, Zelin Peng, Changsong Wen et al.

Affordance segmentation aims to parse 3D objects into functionally distinct parts, bridging recognition and interaction for applications in robotic manipulation, embodied AI, and AR. While recent studies leverage visual or textual prompts to guide this process, they often rely on point cloud encoders as generic feature extractors, overlooking the intrinsic challenges of 3D data such as sparsity, noise, and geometric ambiguity. As a result, 3D features learned in isolation frequently lack clear and semantically consistent functional boundaries. To address this bottleneck, we propose a semantic-grounded learning paradigm that transfers rich semantic knowledge from large-scale 2D Vision Foundation Models (VFMs) into the 3D domain. Specifically, We introduce Cross-Modal Affinity Transfer (CMAT), a pre-training strategy that aligns a 3D encoder with lifted 2D semantics and jointly optimizes reconstruction, affinity, and diversity to yield semantically organized representations. Building on this backbone, we further design the Cross-modal Affordance Segmentation Transformer (CAST), which integrates multi-modal prompts with CMAT-pretrained features to generate precise, prompt-aware segmentation maps. Extensive experiments on standard benchmarks demonstrate that our framework establishes new state-of-the-art results for 3D affordance segmentation.