Haoyu Zhao

Zhuoshi Pan, Yuguang Yao, Gaowen Liu et al.

While state-of-the-art diffusion models (DMs) excel in image generation, concerns regarding their security persist. Earlier research highlighted DMs' vulnerability to data poisoning attacks, but these studies placed stricter requirements than conventional methods like `BadNets' in image classification. This is because the art necessitates modifications to the diffusion training and sampling procedures. Unlike the prior work, we investigate whether BadNets-like data poisoning methods can directly degrade the generation by DMs. In other words, if only the training dataset is contaminated (without manipulating the diffusion process), how will this affect the performance of learned DMs? In this setting, we uncover bilateral data poisoning effects that not only serve an adversarial purpose (compromising the functionality of DMs) but also offer a defensive advantage (which can be leveraged for defense in classification tasks against poisoning attacks). We show that a BadNets-like data poisoning attack remains effective in DMs for producing incorrect images (misaligned with the intended text conditions). Meanwhile, poisoned DMs exhibit an increased ratio of triggers, a phenomenon we refer to as `trigger amplification', among the generated images. This insight can be then used to enhance the detection of poisoned training data. In addition, even under a low poisoning ratio, studying the poisoning effects of DMs is also valuable for designing robust image classifiers against such attacks. Last but not least, we establish a meaningful linkage between data poisoning and the phenomenon of data replications by exploring DMs' inherent data memorization tendencies.

Xingyue Zhao, Wenke Huang, Xingguang Wang et al.

Federated learning enables multiple medical institutions to train a global model without sharing data, yet feature heterogeneity from diverse scanners or protocols remains a major challenge. Many existing works attempt to address this issue by leveraging model representations (e.g., mean feature vectors) to correct local training; however, they often face two key limitations: 1) Incomplete Contextual Representation Learning: Current approaches primarily focus on final-layer features, overlooking critical multi-level cues and thus diluting essential context for accurate segmentation. 2) Layerwise Style Bias Accumulation: Although utilizing representations can partially align global features, these methods neglect domain-specific biases within intermediate layers, allowing style discrepancies to build up and reduce model robustness. To address these challenges, we propose FedBCS to bridge feature representation gaps via domain-invariant contextual prototypes alignment. Specifically, we introduce a frequency-domain adaptive style recalibration into prototype construction that not only decouples content-style representations but also learns optimal style parameters, enabling more robust domain-invariant prototypes. Furthermore, we design a context-aware dual-level prototype alignment method that extracts domain-invariant prototypes from different layers of both encoder and decoder and fuses them with contextual information for finer-grained representation alignment. Extensive experiments on two public datasets demonstrate that our method exhibits remarkable performance.

Haoyu Zhao, Wenhui Dong, Rui Yu et al.

The task of single-source domain generalization (SDG) in medical image segmentation is crucial due to frequent domain shifts in clinical image datasets. To address the challenge of poor generalization across different domains, we introduce a Plug-and-Play module for data augmentation called MoreStyle. MoreStyle diversifies image styles by relaxing low-frequency constraints in Fourier space, guiding the image reconstruction network. With the help of adversarial learning, MoreStyle further expands the style range and pinpoints the most intricate style combinations within latent features. To handle significant style variations, we introduce an uncertainty-weighted loss. This loss emphasizes hard-to-classify pixels resulting only from style shifts while mitigating true hard-to-classify pixels in both MoreStyle-generated and original images. Extensive experiments on two widely used benchmarks demonstrate that the proposed MoreStyle effectively helps to achieve good domain generalization ability, and has the potential to further boost the performance of some state-of-the-art SDG methods. Source code is available at https://github.com/zhaohaoyu376/morestyle.

Haoyu Zhao, Yuliang Gu, Zhou Zhao et al.

In clinical examinations and diagnoses, low-dose computed tomography (LDCT) is crucial for minimizing health risks compared with normal-dose computed tomography (NDCT). However, reducing the radiation dose compromises the signal-to-noise ratio, leading to degraded quality of CT images. To address this, we analyze LDCT denoising task based on experimental results from the frequency perspective, and then introduce a novel self-supervised CT image denoising method called WIA-LD2ND, only using NDCT data. The proposed WIA-LD2ND comprises two modules: Wavelet-based Image Alignment (WIA) and Frequency-Aware Multi-scale Loss (FAM). First, WIA is introduced to align NDCT with LDCT by mainly adding noise to the high-frequency components, which is the main difference between LDCT and NDCT. Second, to better capture high-frequency components and detailed information, Frequency-Aware Multi-scale Loss (FAM) is proposed by effectively utilizing multi-scale feature space. Extensive experiments on two public LDCT denoising datasets demonstrate that our WIA-LD2ND, only uses NDCT, outperforms existing several state-of-the-art weakly-supervised and self-supervised methods. Source code is available at https://github.com/zhaohaoyu376/WI-LD2ND.

Zihao Zhang, Haoran Chen, Haoyu Zhao et al.

Handling complex or nonlinear motion patterns has long posed challenges for video frame interpolation. Although recent advances in diffusion-based methods offer improvements over traditional optical flow-based approaches, they still struggle to generate sharp, temporally consistent frames in scenarios with large motion. To address this limitation, we introduce EDEN, an Enhanced Diffusion for high-quality large-motion vidEo frame iNterpolation. Our approach first utilizes a transformer-based tokenizer to produce refined latent representations of the intermediate frames for diffusion models. We then enhance the diffusion transformer with temporal attention across the process and incorporate a start-end frame difference embedding to guide the generation of dynamic motion. Extensive experiments demonstrate that EDEN achieves state-of-the-art results across popular benchmarks, including nearly a 10% LPIPS reduction on DAVIS and SNU-FILM, and an 8% improvement on DAIN-HD.

Hao Wang, Ying Zhou, Haoyu Zhao et al.

3D Gaussian Splatting (3DGS) has emerged as a pivotal technique for real-time view synthesis in colonoscopy, enabling critical applications such as virtual colonoscopy and lesion tracking. However, the vanilla 3DGS assumes static illumination and that observed appearance depends solely on viewing angle, which causes incompatibility with the photometric variations in colonoscopic scenes induced by dynamic light source/camera. This mismatch forces most 3DGS methods to introduce structure-violating vaporous Gaussian blobs between the camera and tissues to compensate for illumination attenuation, ultimately degrading the quality of 3D reconstructions. Previous works only consider the illumination attenuation caused by light distance, ignoring the physical characters of light source and camera. In this paper, we propose ColIAGS, an improved 3DGS framework tailored for colonoscopy. To mimic realistic appearance under varying illumination, we introduce an Improved Appearance Modeling with two types of illumination attenuation factors, which enables Gaussians to adapt to photometric variations while preserving geometry accuracy. To ensure the geometry approximation condition of appearance modeling, we propose an Improved Geometry Modeling using high-dimensional view embedding to enhance Gaussian geometry attribute prediction. Furthermore, another cosine embedding input is leveraged to generate illumination attenuation solutions in an implicit manner. Comprehensive experimental results on standard benchmarks demonstrate that our proposed ColIAGS achieves the dual capabilities of novel view synthesis and accurate geometric reconstruction. It notably outperforms other state-of-the-art methods by achieving superior rendering fidelity while significantly reducing Depth MSE. Code will be available.

Tong Wang, Xingyue Zhao, Linghao Zhuang et al.

Medical image segmentation is crucial for computer-aided diagnosis, yet privacy constraints hinder data sharing across institutions. Federated learning addresses this limitation, but existing approaches often rely on lightweight architectures that struggle with complex, heterogeneous data. Recently, the Segment Anything Model (SAM) has shown outstanding segmentation capabilities; however, its massive encoder poses significant challenges in federated settings. In this work, we present the first personalized federated SAM framework tailored for heterogeneous data scenarios in medical image segmentation. Our framework integrates two key innovations: (1) a personalized strategy that aggregates only the global parameters to capture cross-client commonalities while retaining the designed L-MoE (Localized Mixture-of-Experts) component to preserve domain-specific features; and (2) a decoupled global-local fine-tuning mechanism that leverages a teacher-student paradigm via knowledge distillation to bridge the gap between the global shared model and the personalized local models, thereby mitigating overgeneralization. Extensive experiments on two public datasets validate that our approach significantly improves segmentation performance, achieves robust cross-domain adaptation, and reduces communication overhead.

Haoyu Zhao, Zhize Li, Peter Richtárik

Federated Averaging (FedAvg, also known as Local-SGD) (McMahan et al., 2017) is a classical federated learning algorithm in which clients run multiple local SGD steps before communicating their update to an orchestrating server. We propose a new federated learning algorithm, FedPAGE, able to further reduce the communication complexity by utilizing the recent optimal PAGE method (Li et al., 2021) instead of plain SGD in FedAvg. We show that FedPAGE uses much fewer communication rounds than previous local methods for both federated convex and nonconvex optimization. Concretely, 1) in the convex setting, the number of communication rounds of FedPAGE is $O(\frac{N^{3/4}}{Sε})$, improving the best-known result $O(\frac{N}{Sε})$ of SCAFFOLD (Karimireddy et al.,2020) by a factor of $N^{1/4}$, where $N$ is the total number of clients (usually is very large in federated learning), $S$ is the sampled subset of clients in each communication round, and $ε$ is the target error; 2) in the nonconvex setting, the number of communication rounds of FedPAGE is $O(\frac{\sqrt{N}+S}{Sε^2})$, improving the best-known result $O(\frac{N^{2/3}}{S^{2/3}ε^2})$ of SCAFFOLD (Karimireddy et al.,2020) by a factor of $N^{1/6}S^{1/3}$, if the sampled clients $S\leq \sqrt{N}$. Note that in both settings, the communication cost for each round is the same for both FedPAGE and SCAFFOLD. As a result, FedPAGE achieves new state-of-the-art results in terms of communication complexity for both federated convex and nonconvex optimization.