Shashank Verma

Ritesh Mehta, Aleksandar Pramov, Shashank Verma

Amyotrophic Lateral Sclerosis (ALS) is characterized as a rapidly progressive neurodegenerative disease that presents individuals with limited treatment options in the realm of medical interventions and therapies. The disease showcases a diverse range of onset patterns and progression trajectories, emphasizing the critical importance of early detection of functional decline to enable tailored care strategies and timely therapeutic interventions. The present investigation, spearheaded by the iDPP@CLEF 2024 challenge, focuses on utilizing sensor-derived data obtained through an app. This data is used to construct various machine learning models specifically designed to forecast the advancement of the ALS Functional Rating Scale-Revised (ALSFRS-R) score, leveraging the dataset provided by the organizers. In our analysis, multiple predictive models were evaluated to determine their efficacy in handling ALS sensor data. The temporal aspect of the sensor data was compressed and amalgamated using statistical methods, thereby augmenting the interpretability and applicability of the gathered information for predictive modeling objectives. The models that demonstrated optimal performance were a naive baseline and ElasticNet regression. The naive model achieved a Mean Absolute Error (MAE) of 0.20 and a Root Mean Square Error (RMSE) of 0.49, slightly outperforming the ElasticNet model, which recorded an MAE of 0.22 and an RMSE of 0.50. Our comparative analysis suggests that while the naive approach yielded marginally better predictive accuracy, the ElasticNet model provides a robust framework for understanding feature contributions.

Shashank Verma, Fengyi Jiang, Xiangning Xue

Biomedical semantic question answering rooted in information retrieval can play a crucial role in keeping up to date with vast, rapidly evolving and ever-growing biomedical literature. A robust system can help researchers, healthcare professionals and even layman users access relevant knowledge grounded in evidence. The BioASQ 2025 Task13b Challenge serves as an important benchmark, offering a competitive platform for advancement of this space. This paper presents the methodologies and results from our participation in this challenge where we built a Retrieval-Augmented Generation (RAG) system that can answer biomedical questions by retrieving relevant PubMed documents and snippets to generate answers. For the retrieval task, we generated dense embeddings from biomedical articles for initial retrieval, and applied an ensemble of finetuned cross-encoders and large language models (LLMs) for re-ranking to identify top relevant documents. Our solution achieved an MAP@10 of 0.1581, placing 10th on the leaderboard for the retrieval task. For answer generation, we employed few-shot prompting of instruction-tuned LLMs. Our system achieved macro-F1 score of 0.95 for yes/no questions (rank 12), Mean Reciprocal Rank (MRR) of 0.64 for factoid questions (rank 1), mean-F1 score of 0.63 for list questions (rank 5), and ROUGE-SU4 F1 score of 0.29 for ideal answers (rank 11).

Rahul K. Dass, Rochan H. Madhusudhana, Erin C. Deye et al.

Supporting learners' understanding of taught skills in online settings is a longstanding challenge. While exercises and chat-based agents can evaluate understanding in limited contexts, this challenge is magnified when learners seek explanations that delve into procedural knowledge (how things are done) and reasoning (why things happen). We hypothesize that an intelligent agent's ability to understand and explain learners' questions about skills can be significantly enhanced using the TMK (Task-Method-Knowledge) model, a Knowledge-based AI framework. We introduce Ivy, an intelligent agent that leverages an LLM and iterative refinement techniques to generate explanations that embody teleological, causal, and compositional principles. Our initial evaluation demonstrates that this approach goes beyond the typical shallow responses produced by an agent with access to unstructured text, thereby substantially improving the depth and relevance of feedback. This can potentially ensure learners develop a comprehensive understanding of skills crucial for effective problem-solving in online environments.

Deepan Das, Noor Mohammed Ghouse, Shashank Verma et al.

We introduce a novel deep neural network architecture that links visual regions to corresponding textual segments including phrases and words. To accomplish this task, our architecture makes use of the rich semantic information available in a joint embedding space of multi-modal data. From this joint embedding space, we extract the associative localization maps that develop naturally, without explicitly providing supervision during training for the localization task. The joint space is learned using a bidirectional ranking objective that is optimized using a $N$-Pair loss formulation. This training mechanism demonstrates the idea that localization information is learned inherently while optimizing a Bidirectional Retrieval objective. The model's retrieval and localization performance is evaluated on MSCOCO and Flickr30K Entities datasets. This architecture outperforms the state of the art results in the semi-supervised phrase localization setting.