Thupten Tsering

Yutong Liu, Feng Xiao, Ziyue Zhang et al.

Multi-level Tibetan spelling correction addresses errors at both the character and syllable levels within a unified model. Existing methods focus mainly on single-level correction and lack effective integration of both levels. Moreover, there are no open-source datasets or augmentation methods tailored for this task in Tibetan. To tackle this, we propose a data augmentation approach using unlabeled text to generate multi-level corruptions, and introduce TiSpell, a semi-masked model capable of correcting both character- and syllable-level errors. Although syllable-level correction is more challenging due to its reliance on global context, our semi-masked strategy simplifies this process. We synthesize nine types of corruptions on clean sentences to create a robust training set. Experiments on both simulated and real-world data demonstrate that TiSpell, trained on our dataset, outperforms baseline models and matches the performance of state-of-the-art approaches, confirming its effectiveness.

Fan Gao, Cheng Huang, Nyima Tashi et al.

To address the severe data scarcity in Tibetan, a low-resource language spoken by over six million people, we introduce TIBSTC-CoT, the large-scale, multi-domain Tibetan dataset automatically constructed via chain-of-thought prompting with large language models (LLMs). TIBSTC-CoT establishes a scalable and reproducible framework for dataset creation in low-resource settings, covering diverse domains and reasoning patterns essential for language understanding and generation. Building on this dataset, we develop the Sunshine-thinking LLM family, a series of Tibetan-centric LLMs equipped with chain-of-thought capabilities. Trained entirely on TIBSTC-CoT, Sunshine-thinking has demonstrated strong reasoning and generation performance, comparable to state-of-the-art (SOTA) multilingual LLMs. Our work marks a significant step toward inclusive AI by enabling high-quality Tibetan language processing through both resource creation and model innovation. All data are available: https://github.com/Vicentvankor/sun-shine.

Cheng Huang, Nyima Tashi, Fan Gao et al.

Tibetan, one of the major low-resource languages in Asia, presents unique linguistic and sociocultural characteristics that pose both challenges and opportunities for AI research. Despite increasing interest in developing AI systems for underrepresented languages, Tibetan has received limited attention due to a lack of accessible data resources, standardized benchmarks, and dedicated tools. This paper provides a comprehensive survey of the current state of Tibetan AI in the AI domain, covering textual and speech data resources, NLP tasks, machine translation, speech recognition, and recent developments in LLMs. We systematically categorize existing datasets and tools, evaluate methods used across different tasks, and compare performance where possible. We also identify persistent bottlenecks such as data sparsity, orthographic variation, and the lack of unified evaluation metrics. Additionally, we discuss the potential of cross-lingual transfer, multi-modal learning, and community-driven resource creation. This survey aims to serve as a foundational reference for future work on Tibetan AI research and encourages collaborative efforts to build an inclusive and sustainable AI ecosystem for low-resource languages.

Abicumaran Uthamacumaran, Mohamed Abdouh, Kinshuk Sengupta et al.

Patient-derived extracellular vesicles (EVs) that contains a complex biological cargo is a valuable source of liquid biopsy diagnostics to aid in early detection, cancer screening, and precision nanotherapeutics. In this study, we predicted that coupling cancer patient blood-derived EVs to time-resolved spectroscopy and artificial intelligence (AI) could provide a robust cancer screening and follow-up tools. Methods: Fluorescence correlation spectroscopy (FCS) measurements were performed on 24 blood samples-derived EVs. Blood samples were obtained from 15 cancer patients (presenting 5 different types of cancers), and 9 healthy controls (including patients with benign lesions). The obtained FCS autocorrelation spectra were processed into power spectra using the Fast-Fourier Transform algorithm and subjected to various machine learning algorithms to distinguish cancer spectra from healthy control spectra. Results and Applications: The performance of AdaBoost Random Forest (RF) classifier, support vector machine, and multilayer perceptron, were tested on selected frequencies in the N=118 power spectra. The RF classifier exhibited a 90% classification accuracy and high sensitivity and specificity in distinguishing the FCS power spectra of cancer patients from those of healthy controls. Further, an image convolutional neural network (CNN), ResNet network, and a quantum CNN were assessed on the power spectral images as additional validation tools. All image-based CNNs exhibited a nearly equal classification performance with an accuracy of roughly 82% and reasonably high sensitivity and specificity scores. Our pilot study demonstrates that AI-algorithms coupled to time-resolved FCS power spectra can accurately and differentially classify the complex patient-derived EVs from different cancer samples of distinct tissue subtypes.