Meiling Chen

Yiqin Zhang, Meiling Chen, Zhengjie Zhang

Whether during the early days of popularization or in the present, the window setting in Computed Tomography (CT) has always been an indispensable part of the CT analysis process. Although research has investigated the capabilities of CT multi-window fusion in enhancing neural networks, there remains a paucity of domain-invariant, intuitively interpretable methodologies for Auto Window Setting. In this work, we propose an plug-and-play module originate from Tanh activation function, which is compatible with mainstream deep learning architectures. Starting from the physical principles of CT, we adhere to the principle of interpretability to ensure the module's reliability for medical implementations. The domain-invariant design facilitates observation of the preference decisions rendered by the adaptive mechanism from a clinically intuitive perspective. This enables the proposed method to be understood not only by experts in neural networks but also garners higher trust from clinicians. We confirm the effectiveness of the proposed method in multiple open-source datasets, yielding 10%~200% Dice improvements on hard segment targets.

Yiqin Zhang, Meiling Chen, Zhengjie Zhang

The application of self-supervised techniques has become increasingly prevalent within medical visualization tasks, primarily due to its capacity to mitigate the data scarcity prevalent in the healthcare sector. The majority of current works are influenced by designs originating in the generic 2D visual domain, which lack the intuitive demonstration of the model's learning process regarding 3D spatial knowledge. Consequently, these methods often fall short in terms of medical interpretability. We propose a method consisting of three sub-tasks to capture the spatially relevant semantics in medical 3D imaging. Their design adheres to observable principles to ensure interpretability, and minimize the performance loss caused thereby as much as possible. By leveraging the enhanced semantic depth offered by the extra dimension in 3D imaging, this approach incorporates multi-granularity spatial relationship modeling to maintain training stability. Experimental findings suggest that our approach is capable of delivering performance that is on par with current methodologies, while facilitating an intuitive understanding of the self-supervised learning process.