IVOct 6, 2020
Anomaly Detection Approach to Identify Early Cases in a Pandemic using Chest X-raysShehroz S. Khan, Faraz Khoshbakhtian, Ahmed Bilal Ashraf
The current COVID-19 pandemic is now getting contained, albeit at the cost of morethan2.3million human lives. A critical phase in any pandemic is the early detection of cases to develop preventive treatments and strategies. In the case of COVID-19,several studies have indicated that chest radiography images of the infected patients show characteristic abnormalities. However, at the onset of a given pandemic, such asCOVID-19, there may not be sufficient data for the affected cases to train models for their robust detection. Hence, supervised classification is ill-posed for this problem because the time spent in collecting large amounts of data from infected persons could lead to the loss of human lives and delays in preventive interventions. Therefore, we formulate the problem of identifying early cases in a pandemic as an anomaly detection problem, in which the data for healthy patients is abundantly available, whereas no training data is present for the class of interest (COVID-19 in our case). To solve this problem, we present several unsupervised deep learning approaches, including convolutional and adversarially trained autoencoder. We tested two settings on a publicly available dataset (COVIDx)by training the model on chest X-rays from (i) only healthy adults, and (ii) healthy and other non-COVID-19 pneumonia, and detected COVID-19 as an anomaly. Afterperforming3-fold cross validation, we obtain a ROC-AUC of0.765. These results are very encouraging and pave the way towards research for ensuring emergency preparedness in future pandemics, especially the ones that could be detected from chest X-rays
LGDec 3, 2018
A Hybrid Instance-based Transfer Learning MethodAzin Asgarian, Parinaz Sobhani, Ji Chao Zhang et al.
In recent years, supervised machine learning models have demonstrated tremendous success in a variety of application domains. Despite the promising results, these successful models are data hungry and their performance relies heavily on the size of training data. However, in many healthcare applications it is difficult to collect sufficiently large training datasets. Transfer learning can help overcome this issue by transferring the knowledge from readily available datasets (source) to a new dataset (target). In this work, we propose a hybrid instance-based transfer learning method that outperforms a set of baselines including state-of-the-art instance-based transfer learning approaches. Our method uses a probabilistic weighting strategy to fuse information from the source domain to the model learned in the target domain. Our method is generic, applicable to multiple source domains, and robust with respect to negative transfer. We demonstrate the effectiveness of our approach through extensive experiments for two different applications.
CVAug 28, 2017
Subspace Selection to Suppress Confounding Source Domain Information in AAM Transfer LearningAzin Asgarian, Ahmed Bilal Ashraf, David Fleet et al.
Active appearance models (AAMs) are a class of generative models that have seen tremendous success in face analysis. However, model learning depends on the availability of detailed annotation of canonical landmark points. As a result, when accurate AAM fitting is required on a different set of variations (expression, pose, identity), a new dataset is collected and annotated. To overcome the need for time consuming data collection and annotation, transfer learning approaches have received recent attention. The goal is to transfer knowledge from previously available datasets (source) to a new dataset (target). We propose a subspace transfer learning method, in which we select a subspace from the source that best describes the target space. We propose a metric to compute the directional similarity between the source eigenvectors and the target subspace. We show an equivalence between this metric and the variance of target data when projected onto source eigenvectors. Using this equivalence, we select a subset of source principal directions that capture the variance in target data. To define our model, we augment the selected source subspace with the target subspace learned from a handful of target examples. In experiments done on six publicly available datasets, we show that our approach outperforms the state of the art in terms of the RMS fitting error as well as the percentage of test examples for which AAM fitting converges to the ground truth.