Rajendra Rana Bhat

Zheng Feng, Rajendra Rana Bhat, Xiaoyong Yuan et al.

Surgery risk assessment is an effective tool for physicians to manage the treatment of patients, but most current research projects fall short in providing a comprehensive platform to evaluate the patients' surgery risk in terms of different complications. The recent evolution of big data analysis techniques makes it possible to develop a real-time platform to dynamically analyze the surgery risk from large-scale patients information. In this paper, we propose the Intelligent Perioperative System (IPS), a real-time system that assesses the risk of postoperative complications (PC) and dynamically interacts with physicians to improve the predictive results. In order to process large volume patients data in real-time, we design the system by integrating several big data computing and storage frameworks with the high through-output streaming data processing components. We also implement a system prototype along with the visualization results to show the feasibility of system design.

Rajendra Rana Bhat, Vivek Viswanath, Xiaolin Li

Transcriptional profiling on microarrays to obtain gene expressions has been used to facilitate cancer diagnosis. We propose a deep generative machine learning architecture (called DeepCancer) that learn features from unlabeled microarray data. These models have been used in conjunction with conventional classifiers that perform classification of the tissue samples as either being cancerous or non-cancerous. The proposed model has been tested on two different clinical datasets. The evaluation demonstrates that DeepCancer model achieves a very high precision score, while significantly controlling the false positive and false negative scores.