Louis ten Bosch

Terry Yi Zhong, Cristian Tejedor-Garcia, Khiet P. Truong et al.

Early-stage Parkinson's disease (EarlyPD) detection from speech is clinically meaningful yet underexplored, and published results are hard to compare because studies differ in datasets, languages, tasks, evaluation protocols, and EarlyPD definitions. To address this issue, we propose the first benchmark for speech-based EarlyPD detection, with a speaker-independent split designed for fair and replicable cross-method evaluation on researcher-accessible datasets. The benchmark covers three common speech tasks and evaluates methods under different training-resource settings. We also present multi-dimensional evaluation breakdowns by dataset, aggregation level, gender, and disease stage to support fine-grained comparisons and clinical adoption. Our results provide a replicable reference and actionable insights, encouraging the adoption of this publicly available benchmark to advance robust and clinically meaningful EarlyPD detection from speech.

Mehtab Ur Rahman, Martha Larson, Louis ten Bosch et al.

Speech recordings are being more frequently used to detect and monitor disease, leading to privacy concerns. Beyond cryptography, protection of speech can be addressed by approaches, such as perturbation, disentanglement, and re-synthesis, that eliminate sensitive information of the speaker, leaving the information necessary for medical analysis purposes. In order for such privacy protective approaches to be developed, clear and systematic specifications of assumptions concerning medical settings and the needs of medical professionals are necessary. In this paper, we propose a Scenario of Use Scheme that incorporates an Attacker Model, which characterizes the adversary against whom the speaker's privacy must be defended, and a Protector Model, which specifies the defense. We discuss the connection of the scheme with previous work on speech privacy. Finally, we present a concrete example of a specified Scenario of Use and a set of experiments about protecting speaker data against gender inference attacks while maintaining utility for Parkinson's detection.

Terry Yi Zhong, Esther Janse, Cristian Tejedor-Garcia et al.

Speech-based Parkinson's disease (PD) detection has gained attention for its automated, cost-effective, and non-intrusive nature. As research studies usually rely on data from diagnostic-oriented speech tasks, this work explores the feasibility of diagnosing PD on the basis of speech data not originally intended for diagnostic purposes, using the Turn-Taking (TT) dataset. Our findings indicate that TT can be as useful as diagnostic-oriented PD datasets like PC-GITA. We also investigate which specific dataset characteristics impact PD classification performance. The results show that concatenating audio recordings and balancing participants' gender and status distributions can be beneficial. Cross-dataset evaluation reveals that models trained on PC-GITA generalize poorly to TT, whereas models trained on TT perform better on PC-GITA. Furthermore, we provide insights into the high variability across folds, which is mainly due to large differences in individual speaker performance.

Martijn Bentum, Louis ten Bosch, Tomas O. Lentz

In this paper we study word stress representations learned by self-supervised speech models (S3M), specifically the Wav2vec 2.0 model. We investigate the S3M representations of word stress for five different languages: Three languages with variable or lexical stress (Dutch, English and German) and two languages with fixed or demarcative stress (Hungarian and Polish). We train diagnostic stress classifiers on S3M embeddings and show that they can distinguish between stressed and unstressed syllables in read-aloud short sentences with high accuracy. We also tested language-specificity effects of S3M word stress. The results indicate that the word stress representations are language-specific, with a greater difference between the set of variable versus the set of fixed stressed languages.