Oscar Carrillo

Carlos J. Barrios H., Frédéric Le Mouël, Oscar Carrillo

We discuss a Quantum-Enhanced Computing Continuum, a heterogeneous, hybrid architecture that integrates quantum processing units (QPUs) within an Edge-Cloud-HPC fabric. Promote sustainability by shifting from performance to "energy-aware integration.' The architecture has three layers: a Physical Layer with shared fiber-optic infrastructure, a Control and Orchestration Layer managed by the user, and an Application Layer with an Adaptive Quantum Classical Fusion (AQCF) framework. Tighter system integration, like moving from cloud coupling to cryogenic logic, reduces energy waste and "thermal footprints.' The aim is a Green Performance Advantage: energy per problem solved in the era of Advanced Computing.

Michael Puentes, Diana Novoa, John Delgado Nivia et al.

Since 2012, in a case-study in Bucaramanga-Colombia, 179 pedestrians died in car accidents, and another 2873 pedestrians were injured. Each day, at least one passerby is involved in a tragedy. Knowing the causes to decrease accidents is crucial, and using system-dynamics to reproduce the collisions' events is critical to prevent further accidents. This work implements simulations to save lives by reducing the city's accidental rate and suggesting new safety policies to implement. Simulation's inputs are video recordings in some areas of the city. Deep Learning analysis of the images results in the segmentation of the different objects in the scene, and an interaction model identifies the primary reasons which prevail in the pedestrians or vehicles' behaviours. The first and most efficient safety policy to implement-validated by our simulations-would be to build speed bumps in specific places before the crossings reducing the accident rate by 80%.

Jens B. Stephansen, Alexander N. Olesen, Mads Olsen et al.

Analysis of sleep for the diagnosis of sleep disorders such as Type-1 Narcolepsy (T1N) currently requires visual inspection of polysomnography records by trained scoring technicians. Here, we used neural networks in approximately 3,000 normal and abnormal sleep recordings to automate sleep stage scoring, producing a hypnodensity graph - a probability distribution conveying more information than classical hypnograms. Accuracy of sleep stage scoring was validated in 70 subjects assessed by six scorers. The best model performed better than any individual scorer (87% versus consensus). It also reliably scores sleep down to 5 instead of 30 second scoring epochs. A T1N marker based on unusual sleep-stage overlaps achieved a specificity of 96% and a sensitivity of 91%, validated in independent datasets. Addition of HLA-DQB1*06:02 typing increased specificity to 99%. Our method can reduce time spent in sleep clinics and automates T1N diagnosis. It also opens the possibility of diagnosing T1N using home sleep studies.