Jyun-Ping Kao

Jyun-Ping Kao, Shinyeong Rho, Shahar Lazarev et al.

Early diagnosis of attention-deficit/hyperactivity disorder (ADHD) in children plays a crucial role in improving outcomes in education and mental health. Diagnosing ADHD using neuroimaging data, however, remains challenging due to heterogeneous presentations and overlapping symptoms with other conditions. To address this, we propose a novel parameter-efficient transfer learning approach that adapts a large-scale 3D convolutional foundation model, pre-trained on CT images, to an MRI-based ADHD classification task. Our method introduces Low-Rank Adaptation (LoRA) in 3D by factorizing 3D convolutional kernels into 2D low-rank updates, dramatically reducing trainable parameters while achieving superior performance. In a five-fold cross-validated evaluation on a public diffusion MRI database, our 3D LoRA fine-tuning strategy achieved state-of-the-art results, with one model variant reaching 71.9% accuracy and another attaining an AUC of 0.716. Both variants use only 1.64 million trainable parameters (over 113x fewer than a fully fine-tuned foundation model). Our results represent one of the first successful cross-modal (CT-to-MRI) adaptations of a foundation model in neuroimaging, establishing a new benchmark for ADHD classification while greatly improving efficiency.

Jyun-Ping Kao, Jiaxing Yang, C. -C. Jay Kuo et al.

Echocardiography is a cornerstone for managing heart failure (HF), with Left Ventricular Ejection Fraction (LVEF) being a critical metric for guiding therapy. However, manual LVEF assessment suffers from high inter-observer variability, while existing Deep Learning (DL) models are often computationally intensive and data-hungry "black boxes" that impede clinical trust and adoption. Here, we propose a backpropagation-free multi-task Green Learning (MTGL) framework that performs simultaneous Left Ventricle (LV) segmentation and LVEF classification. Our framework integrates an unsupervised VoxelHop encoder for hierarchical spatio-temporal feature extraction with a multi-level regression decoder and an XG-Boost classifier. On the EchoNet-Dynamic dataset, our MTGL model achieves state-of-the-art classification and segmentation performance, attaining a classification accuracy of 94.3% and a Dice Similarity Coefficient (DSC) of 0.912, significantly outperforming several advanced 3D DL models. Crucially, our model achieves this with over an order of magnitude fewer parameters, demonstrating exceptional computational efficiency. This work demonstrates that the GL paradigm can deliver highly accurate, efficient, and interpretable solutions for complex medical image analysis, paving the way for more sustainable and trustworthy artificial intelligence in clinical practice.

Jyun-Ping Kao

Large-language models (LLMs) are rapidly being applied to radiology, enabling automated image interpretation and report generation tasks. Their deployment in clinical practice requires both high diagnostic accuracy and low inference latency, which in turn demands powerful hardware. High-performance graphical processing units (GPUs) provide the necessary compute and memory throughput to run large LLMs on imaging data. We review modern GPU architectures (e.g. NVIDIA A100/H100, AMD Instinct MI250X/MI300) and key performance metrics of floating-point throughput, memory bandwidth, VRAM capacity. We show how these hardware capabilities affect radiology tasks: for example, generating reports or detecting findings on CheXpert and MIMIC-CXR images is computationally intensive and benefits from GPU parallelism and tensor-core acceleration. Empirical studies indicate that using appropriate GPU resources can reduce inference time and improve throughput. We discuss practical challenges including privacy, deployment, cost, power and optimization strategies: mixed-precision, quantization, compression, and multi-GPU scaling. Finally, we anticipate that next-generation features (8-bit tensor cores, enhanced interconnect) will further enable on-premise and federated radiology AI. Advancing GPU infrastructure is essential for safe, efficient LLM-based radiology diagnostics.