Min Zhang

Xiaojie Li, Bei Wang, Jianlong Wu et al.

The success of contrastive learning depends on the construction and utilization of high-quality positive pairs. However, current methods face critical limitations on two fronts: on the construction side, both handcrafted and generative augmentations often suffer from limited diversity and risk semantic corruption; on the learning side, the absence of a quality assessment mechanism leads to suboptimal supervision where all pairs are treated equally. To tackle these challenges, we propose GenView++, a unified framework that addresses both fronts by introducing two synergistic innovations. To improve pair construction, GenView++ introduces a multi-source adaptive view generation mechanism to synthesize diverse yet semantically coherent views by dynamically modulating generative parameters across image-conditioned, text-conditioned, and image-text-conditioned strategies. Second, a quality-driven contrastive learning mechanism assesses each pair's semantic alignment and diversity to dynamically reweight their training contribution, prioritizing high-quality pairs while suppressing redundant or misaligned pairs. Extensive experiments demonstrate the effectiveness of GenView++ across both vision and vision-language tasks. For vision representation learning, it improves MoCov2 by +2.5% on ImageNet linear classification. For vision-language learning, it raises the average zero-shot classification accuracy by +12.31% over CLIP and +5.31% over SLIP across ten datasets, and further improves Flickr30k text retrieval R@5 by +3.2%. The code is available at https://github.com/xiaojieli0903/GenViewPlusPlus.

Guodong Du, Xuanning Zhou, Junlin Li et al.

Cross-capability transfer is a key challenge in large language model (LLM) research, with applications in multi-task integration, model compression, and continual learning. Recent works like FuseLLM and FuseChat have demonstrated the potential of transferring multiple model capabilities to lightweight models, enhancing adaptability and efficiency, which motivates our investigation into more efficient cross-capability transfer methods. However, existing approaches primarily focus on small, homogeneous models, limiting their applicability. For large, heterogeneous models, knowledge distillation with full-parameter fine-tuning often overlooks the student model's intrinsic capacity and risks catastrophic forgetting, while PEFT methods struggle to effectively absorb knowledge from source LLMs. To address these issues, we introduce GraftLLM, a novel method that stores source model capabilities in a target model with SkillPack format. This approach preserves general capabilities, reduces parameter conflicts, and supports forget-free continual learning and model fusion. We employ a module-aware adaptive compression strategy to compress parameter updates, ensuring efficient storage while maintaining task-specific knowledge. The resulting SkillPack serves as a compact and transferable knowledge carrier, ideal for heterogeneous model fusion and continual learning. Experiments across various scenarios demonstrate that GraftLLM outperforms existing techniques in knowledge transfer, knowledge fusion, and forget-free learning, providing a scalable and efficient solution for cross-capability transfer. The code is publicly available at: https://github.com/duguodong7/GraftLLM.

Ming Li, Zihuai He, Min Zhang et al.

With the advance of high-throughput sequencing technologies, it has become feasible to investigate the influence of the entire spectrum of sequencing variations on complex human diseases. Although association studies utilizing the new sequencing technologies hold great promise to unravel novel genetic variants, especially rare genetic variants that contribute to human diseases, the statistical analysis of high-dimensional sequencing data remains a challenge. Advanced analytical methods are in great need to facilitate high-dimensional sequencing data analyses. In this article, we propose a generalized genetic random field (GGRF) method for association analyses of sequencing data. Like other similarity-based methods (e.g., SIMreg and SKAT), the new method has the advantages of avoiding the need to specify thresholds for rare variants and allowing for testing multiple variants acting in different directions and magnitude of effects. The method is built on the generalized estimating equation framework and thus accommodates a variety of disease phenotypes (e.g., quantitative and binary phenotypes). Moreover, it has a nice asymptotic property, and can be applied to small-scale sequencing data without need for small-sample adjustment. Through simulations, we demonstrate that the proposed GGRF attains an improved or comparable power over a commonly used method, SKAT, under various disease scenarios, especially when rare variants play a significant role in disease etiology. We further illustrate GGRF with an application to a real dataset from the Dallas Heart Study. By using GGRF, we were able to detect the association of two candidate genes, ANGPTL3 and ANGPTL4, with serum triglyceride.