Jiewen Tan

Jiewen Tan, Junnan Xue, Shing Shin Cheng et al.

Achieving both efficient pushability (propulsion transmission) and proximally concentrated bending for steerability is challenging for magnetically actuated soft catheters: higher axial/bending stiffness improves force transmission but reduces steerability, whereas lower stiffness enables large, proximally concentrated bending yet increases kinking/buckling risk under compressive push loads. To address this trade-off, we propose a stiffness-optimized multi-segment magnetically actuated catheter (SO-MAC) that integrates a decoupled steering-advancement mechanism with a gradient-stiffness architecture. The SO-MAC concentrates bending about a stable proximal pivot during advancement while the distal section passively self-straightens to transmit propulsion, aided by the optimized stiffness distribution and elastic recovery of the spring backbone against friction-induced kinking/buckling. Over $0{-}180^{\circ}$ combined steering and advancement, the pivot remained stable and the distal tip advanced near-straight toward the target direction. A 1.5 mm-diameter SO-MAC achieved up to $180^{\circ}$ steering with a 3 mm bending radius at its 10 mm tip, with an average shape error of $1.39 \pm 0.56$ mm and a steering-pivot error of $0.35 \pm 0.10$ mm. Visual feedback control in a bronchial phantom further confirmed robust navigation through highly curved, bifurcating paths.

Wenxuan Xie, Yuelin Zhang, Qingpeng Ding et al.

Wireless localization of permanent magnets enables occlusion-free guidance for medical interventions, yet its practical accuracy is fundamentally limited by two coupled challenges: the poor observability of conventional planar sensor arrays and the simulation-to-reality (Sim-to-Real) gap of learning-based estimators. To address these issues, this article presents a unified framework that combines information-theoretic sensor geometry optimization with physics-aware deep learning. First, a rigorous Fisher Information Matrix (FIM)-based evaluation framework is established to quantify geometry-induced observability limitations. The results show that a staggered split-array topology provides a substantially stronger observability foundation for localization while remaining compatible with practical external deployment. Second, building on this optimized sensing configuration, we propose Phy-GAANet, a calibration-free estimator trained entirely on hardware-aware synthetic data. By incorporating Physics-Informed Features (PIF) for saturation modeling and Geometry-Aware Attention (GAA) for preserving cross-layer vector structure, the network effectively bridges the Sim-to-Real gap. Extensive real-world experiments demonstrate state-of-the-art performance, achieving a position error of 1.84 mm and an orientation error of 3.18 degrees at a refresh rate exceeding 270 Hz. The proposed method consistently outperforms classical Levenberg--Marquardt solvers and generic convolutional baselines, particularly in suppressing catastrophic outliers and maintaining robustness in challenging near-field boundary regions. Beyond the proposed network, the FIM-guided analysis also provides a framework for sensor geometry design in magnetic localization systems under practical deployment constraints.

Gheorghe Comanici, Eric Bieber, Mike Schaekermann et al. · amazon-science, baidu

In this report, we introduce the Gemini 2.X model family: Gemini 2.5 Pro and Gemini 2.5 Flash, as well as our earlier Gemini 2.0 Flash and Flash-Lite models. Gemini 2.5 Pro is our most capable model yet, achieving SoTA performance on frontier coding and reasoning benchmarks. In addition to its incredible coding and reasoning skills, Gemini 2.5 Pro is a thinking model that excels at multimodal understanding and it is now able to process up to 3 hours of video content. Its unique combination of long context, multimodal and reasoning capabilities can be combined to unlock new agentic workflows. Gemini 2.5 Flash provides excellent reasoning abilities at a fraction of the compute and latency requirements and Gemini 2.0 Flash and Flash-Lite provide high performance at low latency and cost. Taken together, the Gemini 2.X model generation spans the full Pareto frontier of model capability vs cost, allowing users to explore the boundaries of what is possible with complex agentic problem solving.