Cigdem Sazak

Shuaa S. Alharbi, Cigdem Sazak, Carl J. Nelson et al.

A wide range of biomedical applications requires enhancement, detection, quantification and modelling of curvilinear structures in 2D and 3D images. Curvilinear structure enhancement is a crucial step for further analysis, but many of the enhancement approaches still suffer from contrast variations and noise. This can be addressed using a multiscale approach that produces a better quality enhancement for low contrast and noisy images compared with a single-scale approach in a wide range of biomedical images. Here, we propose the Multiscale Top-Hat Tensor (MTHT) approach, which combines multiscale morphological filtering with a local tensor representation of curvilinear structures in 2D and 3D images. The proposed approach is validated on synthetic and real data and is also compared to the state-of-the-art approaches. Our results show that the proposed approach achieves high-quality curvilinear structure enhancement in synthetic examples and in a wide range of 2D and 3D images.

Cigdem Sazak, Carl J. Nelson, Boguslaw Obara

Enhancement and detection of 3D vessel-like structures has long been an open problem as most existing image processing methods fail in many aspects, including a lack of uniform enhancement between vessels of different radii and a lack of enhancement at the junctions. Here, we propose a method based on mathematical morphology to enhance 3D vessel-like structures in biomedical images. The proposed method, 3D bowler-hat transform, combines sphere and line structuring elements to enhance vessel-like structures. The proposed method is validated on synthetic and real data and compared with state-of-the-art methods. Our results show that the proposed method achieves a high-quality vessel-like structures enhancement in both synthetic and real biomedical images, and is able to cope with variations in vessels thickness throughout vascular networks while remaining robust at junctions.