H. D. Cheng

Fei Xu, Yingtao Zhang, Min Xian et al.

Breast cancer investigation is of great significance, and developing tumor detection methodologies is a critical need. However, it is a challenging task for breast ultrasound due to the complicated breast structure and poor quality of the images. In this paper, we propose a novel tumor saliency estimation model guided by enriched breast anatomy knowledge to localize the tumor. Firstly, the breast anatomy layers are generated by a deep neural network. Then we refine the layers by integrating a non-semantic breast anatomy model to solve the problems of incomplete mammary layers. Meanwhile, a new background map generation method weighted by the semantic probability and spatial distance is proposed to improve the performance. The experiment demonstrates that the proposed method with the new background map outperforms four state-of-the-art TSE models with increasing 10% of F_meansure on the BUS public dataset.

Fei Xu, Yingtao Zhang, Min Xian et al.

Tumor saliency estimation aims to localize tumors by modeling the visual stimuli in medical images. However, it is a challenging task for breast ultrasound due to the complicated anatomic structure of the breast and poor image quality; and existing saliency estimation approaches only model generic visual stimuli, e.g., local and global contrast, location, and feature correlation, and achieve poor performance for tumor saliency estimation. In this paper, we propose a novel optimization model to estimate tumor saliency by utilizing breast anatomy. First, we model breast anatomy and decompose breast ultrasound image into layers using Neutro-Connectedness; then utilize the layers to generate the foreground and background maps; and finally propose a novel objective function to estimate the tumor saliency by integrating the foreground map, background map, adaptive center bias, and region-based correlation cues. The extensive experiments demonstrate that the proposed approach obtains more accurate foreground and background maps with the assistance of the breast anatomy; especially, for the images having large or small tumors; meanwhile, the new objective function can handle the images without tumors. The newly proposed method achieves state-of-the-art performance when compared to eight tumor saliency estimation approaches using two breast ultrasound datasets.