Jihwan Shin

Taewon Kim, Jihwan Shin, Hyomin Kim et al.

DNA language models are increasingly used to represent genomic sequence, yet their effectiveness depends critically on how raw nucleotides are converted into model inputs. Unlike natural language, DNA offers no canonical boundaries, making fixed tokenizations a brittle design choice under shifts, indels, and local repeats. We introduce DNAChunker, a masked DNA language model that incorporates a learnable adaptive segmentation module to produce context-dependent, variable-length units. Building on a dynamic segmentation procedure, DNAChunker learns to allocate finer granularity to functionally enriched regions while compressing repetitive or redundant sequence. We pretrain DNAChunker on the human reference genome and evaluate it across five benchmarks, where it consistently improves over strong fixed-tokenization baselines. Further analyses and ablations indicate that unlike fixed tokenizations, segmentation is learned in a biologically-informed, mutation-resilient manner.

Gyuejeong Lee, Jihwan Shin, Daeyoung Choi

Heterogeneity in data distributions and model architectures remains a significant challenge in federated learning (FL). Various heterogeneous FL (HtFL) approaches have recently been proposed to address this challenge. Among them, prototype-based FL (PBFL) has emerged as a practical framework that only shares per-class mean activations from the penultimate layer. However, PBFL approaches often suffer from suboptimal prototype separation, limiting their discriminative power. We propose Prototype Normalization (ProtoNorm), a novel PBFL framework that addresses this limitation through two key components: Prototype Alignment (PA) and Prototype Upscaling (PU). The PA method draws inspiration from the Thomson problem in classical physics, optimizing global prototype configurations on a unit sphere to maximize angular separation; subsequently, the PU method increases prototype magnitudes to enhance separation in Euclidean space. Extensive evaluations on benchmark datasets show that our approach better separates prototypes and thus consistently outperforms existing HtFL approaches. Notably, since ProtoNorm inherits the communication efficiency of PBFL and the PA is performed server-side, it is particularly suitable for resource-constrained environments.