Ethan Lin

McKell Woodland, John Wood, Brian M. Anderson et al.

Although generative adversarial networks (GANs) have shown promise in medical imaging, they have four main limitations that impeded their utility: computational cost, data requirements, reliable evaluation measures, and training complexity. Our work investigates each of these obstacles in a novel application of StyleGAN2-ADA to high-resolution medical imaging datasets. Our dataset is comprised of liver-containing axial slices from non-contrast and contrast-enhanced computed tomography (CT) scans. Additionally, we utilized four public datasets composed of various imaging modalities. We trained a StyleGAN2 network with transfer learning (from the Flickr-Faces-HQ dataset) and data augmentation (horizontal flipping and adaptive discriminator augmentation). The network's generative quality was measured quantitatively with the Fréchet Inception Distance (FID) and qualitatively with a visual Turing test given to seven radiologists and radiation oncologists. The StyleGAN2-ADA network achieved a FID of 5.22 ($\pm$ 0.17) on our liver CT dataset. It also set new record FIDs of 10.78, 3.52, 21.17, and 5.39 on the publicly available SLIVER07, ChestX-ray14, ACDC, and Medical Segmentation Decathlon (brain tumors) datasets. In the visual Turing test, the clinicians rated generated images as real 42% of the time, approaching random guessing. Our computational ablation study revealed that transfer learning and data augmentation stabilize training and improve the perceptual quality of the generated images. We observed the FID to be consistent with human perceptual evaluation of medical images. Finally, our work found that StyleGAN2-ADA consistently produces high-quality results without hyperparameter searches or retraining.

Ethan Lin, Zhiyuan Peng, Yi Fang

Recent studies have evaluated the creativity/novelty of large language models (LLMs) primarily from a semantic perspective, using benchmarks from cognitive science. However, accessing the novelty in scholarly publications is a largely unexplored area in evaluating LLMs. In this paper, we introduce a scholarly novelty benchmark (SchNovel) to evaluate LLMs' ability to assess novelty in scholarly papers. SchNovel consists of 15000 pairs of papers across six fields sampled from the arXiv dataset with publication dates spanning 2 to 10 years apart. In each pair, the more recently published paper is assumed to be more novel. Additionally, we propose RAG-Novelty, which simulates the review process taken by human reviewers by leveraging the retrieval of similar papers to assess novelty. Extensive experiments provide insights into the capabilities of different LLMs to assess novelty and demonstrate that RAG-Novelty outperforms recent baseline models.

Ethan Lin, Linxi Zhao, Atharva Sehgal et al.

Text-based visual descriptors--ranging from simple class names to more descriptive phrases--are widely used in visual concept discovery and image classification with vision-language models (VLMs). Their effectiveness, however, depends on a complex interplay of factors, including semantic clarity, presence in the VLM's pre-training data, and how well the descriptors serve as a meaningful representation space. In this work, we systematically analyze descriptor quality along two key dimensions: (1) representational capacity, and (2) relationship with VLM pre-training data. We evaluate a spectrum of descriptor generation methods, from zero-shot LLM-generated prompts to iteratively refined descriptors. Motivated by ideas from representation alignment and language understanding, we introduce two alignment-based metrics--Global Alignment and CLIP Similarity--that move beyond accuracy. These metrics shed light on how different descriptor generation strategies interact with foundation model properties, offering new ways to study descriptor effectiveness beyond accuracy evaluations.