Paul Klein

Jaeyoung Huh, Paul Klein, Gareth Funka-Lea et al.

Intra-cardiac echocardiography (ICE) is a crucial imaging modality used in electrophysiology (EP) and structural heart disease (SHD) interventions, providing realtime, high-resolution views from within the heart. Despite its advantages, effective manipulation of the ICE catheter requires significant expertise, which can lead to inconsistent outcomes, especially among less experienced operators. To address this challenge, we propose an AIdriven view guidance system that operates in a continuous closed-loop with human-in-the-loop feedback, designed to assist users in navigating ICE imaging without requiring specialized knowledge. Specifically, our method models the relative position and orientation vectors between arbitrary views and clinically defined ICE views in a spatial coordinate system. It guides users on how to manipulate the ICE catheter to transition from the current view to the desired view over time. By operating in a closedloop configuration, the system continuously predicts and updates the necessary catheter manipulations, ensuring seamless integration into existing clinical workflows. The effectiveness of the proposed system is demonstrated through a simulation-based performance evaluation using real clinical data, achieving an 89% success rate with 6,532 test cases. Additionally, a semi-simulation experiment with human-in-the-loop testing validated the feasibility of continuous yet discrete guidance. These results underscore the potential of the proposed method to enhance the accuracy and efficiency of ICE imaging procedures.

Lisa Tse, Peter Mountney, Paul Klein et al.

The design and performance of computer vision algorithms are greatly influenced by the hardware on which they are implemented. CPUs, multi-core CPUs, FPGAs and GPUs have inspired new algorithms and enabled existing ideas to be realized. This is notably the case with GPUs, which has significantly changed the landscape of computer vision research through deep learning. As the end of Moores law approaches, researchers and hardware manufacturers are exploring alternative hardware computing paradigms. Quantum computers are a very promising alternative and offer polynomial or even exponential speed-ups over conventional computing for some problems. This paper presents a novel approach to image segmentation that uses new quantum computing hardware. Segmentation is formulated as a graph cut problem that can be mapped to the quantum approximate optimization algorithm (QAOA). This algorithm can be implemented on current and near-term quantum computers. Encouraging results are presented on artificial and medical imaging data. This represents an important, practical step towards leveraging quantum computers for computer vision.