Moni Shahar

Ronny Luss, Saharon Rosset, Moni Shahar

Isotonic regression is a nonparametric approach for fitting monotonic models to data that has been widely studied from both theoretical and practical perspectives. However, this approach encounters computational and statistical overfitting issues in higher dimensions. To address both concerns, we present an algorithm, which we term Isotonic Recursive Partitioning (IRP), for isotonic regression based on recursively partitioning the covariate space through solution of progressively smaller "best cut" subproblems. This creates a regularized sequence of isotonic models of increasing model complexity that converges to the global isotonic regression solution. The models along the sequence are often more accurate than the unregularized isotonic regression model because of the complexity control they offer. We quantify this complexity control through estimation of degrees of freedom along the path. Success of the regularized models in prediction and IRPs favorable computational properties are demonstrated through a series of simulated and real data experiments. We discuss application of IRP to the problem of searching for gene--gene interactions and epistasis, and demonstrate it on data from genome-wide association studies of three common diseases.

Idan Sulami, Alon Itzkovitch, Michael R. Kearney et al.

Microclimate models are essential for linking climate to ecological processes, yet most physically based frameworks estimate temperature independently for each spatial unit and rely on simplified representations of lateral heat exchange. As a result, the spatial scales over which surrounding environmental conditions influence local microclimates remain poorly quantified. Here, we show how remote sensing can help quantify the contribution of spatial context to microclimate temperature predictions. Building on convolutional neural network principles, we designed a task-specific deep neural network and trained a series of models in which the spatial extent of input data was systematically varied. Drone-derived spatial layers and meteorological data were used to predict ground temperature at a focal location, allowing direct assessment of how prediction accuracy changes with increasing spatial context. Our results show that incorporating spatially adjacent information substantially improves prediction accuracy, with diminishing returns beyond spatial extents of approximately 5-7 m. This characteristic scale indicates that ground temperatures are influenced not only by local surface properties, but also by horizontal heat transfer and radiative interactions operating across neighboring microhabitats. The magnitude of spatial effects varied systematically with time of day, microhabitat type, and local environmental characteristics, highlighting context-dependent spatial coupling in microclimate formation. By treating deep learning as a diagnostic tool rather than solely a predictive one, our approach provides a general and transferable method for quantifying spatial dependencies in microclimate models and informing the development of hybrid mechanistic-data-driven approaches that explicitly account for spatial interactions while retaining physical interpretability.

Naama Hadad, Lior Wolf, Moni Shahar

We address the problem of disentanglement of factors that generate a given data into those that are correlated with the labeling and those that are not. Our solution is simpler than previous solutions and employs adversarial training. First, the part of the data that is correlated with the labels is extracted by training a classifier. Then, the other part is extracted such that it enables the reconstruction of the original data but does not contain label information. The utility of the new method is demonstrated on visual datasets as well as on financial data. Our code is available at https://github.com/naamahadad/A-Two-Step-Disentanglement-Method

Haim Fisher, Moni Shahar, Yehezkel S. Resheff

Deep learning models for image classification have become standard tools in recent years. A well known vulnerability of these models is their susceptibility to adversarial examples. These are generated by slightly altering an image of a certain class in a way that is imperceptible to humans but causes the model to classify it wrongly as another class. Many algorithms have been proposed to address this problem, falling generally into one of two categories: (i) building robust classifiers (ii) directly detecting attacked images. Despite the good performance of these detectors, we argue that in a white-box setting, where the attacker knows the configuration and weights of the network and the detector, they can overcome the detector by running many examples on a local copy, and sending only those that were not detected to the actual model. This problem is common in security applications where even a very good model is not sufficient to ensure safety. In this paper we propose to overcome this inherent limitation of any static defence with randomization. To do so, one must generate a very large family of detectors with consistent performance, and select one or more of them randomly for each input. For the individual detectors, we suggest the method of neural fingerprints. In the training phase, for each class we repeatedly sample a tiny random subset of neurons from certain layers of the network, and if their average is sufficiently different between clean and attacked images of the focal class they are considered a fingerprint and added to the detector bank. During test time, we sample fingerprints from the bank associated with the label predicted by the model, and detect attacks using a likelihood ratio test. We evaluate our detectors on ImageNet with different attack methods and model architectures, and show near-perfect detection with low rates of false detection.

Irena Girshovitz, Atai Ambus, Moni Shahar et al.

Background: The use of Electronic Health Records (EHRs) for epidemiological studies and artificial intelligence (AI) training is increasing rapidly. The reliability of the results depends on the accuracy and completeness of EHR data. However, EHR data often contain significant quality issues, including misrepresentations of subpopulations, biases, and systematic errors, as they are primarily collected for clinical and billing purposes. Existing quality assessment methods remain insufficient, lacking systematic procedures to assess data fitness for research. Methods: We present the Medical Data Pecking approach, which adapts unit testing and coverage concepts from software engineering to identify data quality concerns. We demonstrate our approach using the Medical Data Pecking Tool (MDPT), which consists of two main components: (1) an automated test generator that uses large language models and grounding techniques to create a test suite from data and study descriptions, and (2) a data testing framework that executes these tests, reporting potential errors and coverage. Results: We evaluated MDPT on three datasets: All of Us (AoU), MIMIC-III, and SyntheticMass, generating 55-73 tests per cohort across four conditions. These tests correctly identified 20-43 non-aligned or non-conforming data issues. We present a detailed analysis of the LLM-generated test suites in terms of reference grounding and value accuracy. Conclusion: Our approach incorporates external medical knowledge to enable context-sensitive data quality testing as part of the data analysis workflow to improve the validity of its outcomes. Our approach tackles these challenges from a quality assurance perspective, laying the foundation for further development such as additional data modalities and improved grounding methods.

Yehezkel S. Resheff, Yanai Elazar, Moni Shahar et al.

Latent factor models for recommender systems represent users and items as low dimensional vectors. Privacy risks of such systems have previously been studied mostly in the context of recovery of personal information in the form of usage records from the training data. However, the user representations themselves may be used together with external data to recover private user information such as gender and age. In this paper we show that user vectors calculated by a common recommender system can be exploited in this way. We propose the privacy-adversarial framework to eliminate such leakage of private information, and study the trade-off between recommender performance and leakage both theoretically and empirically using a benchmark dataset. An advantage of the proposed method is that it also helps guarantee fairness of results, since all implicit knowledge of a set of attributes is scrubbed from the representations used by the model, and thus can't enter into the decision making. We discuss further applications of this method towards the generation of deeper and more insightful recommendations.

Yehezkel S. Resheff, Moni Shahar

Inferring user characteristics such as demographic attributes is of the utmost importance in many user-centric applications. Demographic data is an enabler of personalization, identity security, and other applications. Despite that, this data is sensitive and often hard to obtain. Previous work has shown that purchase history can be used for multi-task prediction of many demographic fields such as gender and marital status. Here we present an embedding based method to integrate multifaceted sequences of transaction data, together with auxiliary relational tables, for better user modeling and demographic prediction.