Qing Yun Li

Ryan J. Urbanowicz, Harsh Bandhey, Brendan T. Keenan et al.

While machine learning (ML) includes a valuable array of tools for analyzing biomedical data, significant time and expertise is required to assemble effective, rigorous, and unbiased pipelines. Automated ML (AutoML) tools seek to facilitate ML application by automating a subset of analysis pipeline elements. In this study we develop and validate a Simple, Transparent, End-to-end Automated Machine Learning Pipeline (STREAMLINE) and apply it to investigate the added utility of photography-based phenotypes for predicting obstructive sleep apnea (OSA); a common and underdiagnosed condition associated with a variety of health, economic, and safety consequences. STREAMLINE is designed to tackle biomedical binary classification tasks while adhering to best practices and accommodating complexity, scalability, reproducibility, customization, and model interpretation. Benchmarking analyses validated the efficacy of STREAMLINE across data simulations with increasingly complex patterns of association. Then we applied STREAMLINE to evaluate the utility of demographics (DEM), self-reported comorbidities (DX), symptoms (SYM), and photography-based craniofacial (CF) and intraoral (IO) anatomy measures in predicting any OSA or moderate/severe OSA using 3,111 participants from Sleep Apnea Global Interdisciplinary Consortium (SAGIC). OSA analyses identified a significant increase in ROC-AUC when adding CF to DEM+DX+SYM to predict moderate/severe OSA. A consistent but non-significant increase in PRC-AUC was observed with the addition of each subsequent feature set to predict any OSA, with CF and IO yielding minimal improvements. Application of STREAMLINE to OSA data suggests that CF features provide additional value in predicting moderate/severe OSA, but neither CF nor IO features meaningfully improved the prediction of any OSA beyond established demographics, comorbidity and symptom characteristics.

Chongjie Si, Xuehui Wang, Xue Yang et al.

Adapting pre-trained foundation models for various downstream tasks has been prevalent in artificial intelligence. Due to the vast number of tasks and high costs, adjusting all parameters becomes unfeasible. To mitigate this, several fine-tuning techniques have been developed to update the pre-trained model weights in a more resource-efficient manner, such as through low-rank adjustments. Yet, almost all of these methods focus on linear weights, neglecting the intricacies of parameter spaces in higher dimensions like 4D. Alternatively, some methods can be adapted for high-dimensional parameter space by compressing changes in the original space into two dimensions and then employing low-rank matrix adaptations. However, these approaches destructs the structural integrity of the involved high-dimensional spaces. To tackle the diversity of dimensional spaces across different foundation models and provide a more precise representation of the changes within these spaces, this paper introduces a generalized parameter-efficient fine-tuning framework, designed for various dimensional parameter space. Specifically, our method asserts that changes in each dimensional parameter space are based on a low-rank core space which maintains the consistent topological structure with the original space. It then models the changes through this core space alongside corresponding weights to reconstruct alterations in the original space. It effectively preserves the structural integrity of the change of original N-dimensional parameter space, meanwhile models it via low-rank tensor adaptation. Extensive experiments on computer vision, natural language processing and multi-modal tasks validate the effectiveness of our method.

Hongxin Li, Jingran Su, Jingfan Chen et al.

Building autonomous agents that perceive and operate graphical user interfaces (GUIs) like humans has long been a vision in the field of artificial intelligence. Central to these agents is the capability for GUI interaction, which involves GUI understanding and planning capabilities. Existing methods have tried developing GUI agents based on the multi-modal comprehension ability of vision-language models (VLMs). However, the limited scenario, insufficient size, and heterogeneous action spaces hinder the progress of building generalist GUI agents. To resolve these issues, this paper proposes \textbf{UIPro}, a novel generalist GUI agent trained with extensive multi-platform and multi-task GUI interaction data, coupled with a unified action space. We first curate a comprehensive dataset encompassing 20.6 million GUI understanding tasks to pre-train UIPro, granting it a strong GUI grounding capability, which is key to downstream GUI agent tasks. Subsequently, we establish a unified action space to harmonize heterogeneous GUI agent task datasets and produce a merged dataset to foster the action prediction ability of UIPro via continued fine-tuning. Experimental results demonstrate UIPro's superior performance across multiple GUI task benchmarks on various platforms, highlighting the effectiveness of our approach.