Deep learning has been widely employed to solve the Electrical Impedance Tomography (EIT) image reconstruction problem. Most existing physical model-based and learning-based approaches focus on 2D EIT image reconstruction. However, when they are directly extended to the 3D domain, the reconstruction performance in terms of image quality and noise robustness is hardly guaranteed mainly due to the significant increase in dimensionality. This paper presents a learning-based approach for 3D EIT image reconstruction, which is named Transposed convolution with Neurons Network (TN-Net). Simulation and experimental results show the superior performance and generalization ability of TN-Net compared with prevailing 3D EIT image reconstruction algorithms.
Multi-frequency Electrical Impedance Tomography (mfEIT) is a promising biomedical imaging technique that estimates tissue conductivities across different frequencies. Current state-of-the-art (SOTA) algorithms, which rely on supervised learning and Multiple Measurement Vectors (MMV), require extensive training data, making them time-consuming, costly, and less practical for widespread applications. Moreover, the dependency on training data in supervised MMV methods can introduce erroneous conductivity contrasts across frequencies, posing significant concerns in biomedical applications. To address these challenges, we propose a novel unsupervised learning approach based on Multi-Branch Attention Image Prior (MAIP) for mfEIT reconstruction. Our method employs a carefully designed Multi-Branch Attention Network (MBA-Net) to represent multiple frequency-dependent conductivity images and simultaneously reconstructs mfEIT images by iteratively updating its parameters. By leveraging the implicit regularization capability of the MBA-Net, our algorithm can capture significant inter- and intra-frequency correlations, enabling robust mfEIT reconstruction without the need for training data. Through simulation and real-world experiments, our approach demonstrates performance comparable to, or better than, SOTA algorithms while exhibiting superior generalization capability. These results suggest that the MAIP-based method can be used to improve the reliability and applicability of mfEIT in various settings.
Unsupervised learning methods, such as Deep Image Prior (DIP), have shown great potential in tomographic imaging due to their training-data-free nature and high generalization capability. However, their reliance on numerous network parameter iterations results in high computational costs, limiting their practical application, particularly in complex 3D or time-sequence tomographic imaging tasks. To overcome these challenges, we propose Deep Dynamic Image Prior (D2IP), a novel framework for 3D time-sequence imaging. D2IP introduces three key strategies - Unsupervised Parameter Warm-Start (UPWS), Temporal Parameter Propagation (TPP), and a customized lightweight reconstruction backbone, 3D-FastResUNet - to accelerate convergence, enforce temporal coherence, and improve computational efficiency. Experimental results on both simulated and clinical pulmonary datasets demonstrate that D2IP enables fast and accurate 3D time-sequence Electrical Impedance Tomography (tsEIT) reconstruction. Compared to state-of-the-art baselines, D2IP delivers superior image quality, with a 24.8% increase in average MSSIM and an 8.1% reduction in ERR, alongside significantly reduced computational time (7.1x faster), highlighting its promise for clinical dynamic pulmonary imaging.
Electrical Impedance Tomography (EIT) is a non-invasive, low-cost bedside imaging modality with high temporal resolution, making it suitable for bedside monitoring. However, its inherently ill-posed inverse problem poses significant challenges for accurate image reconstruction. Deep learning (DL)-based approaches have shown promise but often rely on complex network architectures with a large number of parameters, limiting efficiency and scalability. Here, we propose an Ultra-Lightweight Quantum-Assisted Inference (QuantEIT) framework for EIT image reconstruction. QuantEIT leverages a Quantum-Assisted Network (QA-Net), combining parallel 2-qubit quantum circuits to generate expressive latent representations that serve as implicit nonlinear priors, followed by a single linear layer for conductivity reconstruction. This design drastically reduces model complexity and parameter number. Uniquely, QuantEIT operates in an unsupervised, training-data-free manner and represents the first integration of quantum circuits into EIT image reconstruction. Extensive experiments on simulated and real-world 2D and 3D EIT lung imaging data demonstrate that QuantEIT outperforms conventional methods, achieving comparable or superior reconstruction accuracy using only 0.2% of the parameters, with enhanced robustness to noise.
Advancements in high-throughput biomedical applications require real-time, large field-of-view (FOV) imaging. While current 2D lens-free imaging (LFI) systems improve FOV, they are often hindered by time-consuming multi-position measurements, extensive data pre-processing, and strict optical parameterization, limiting their application to static, thin samples. To overcome these limitations, we introduce GenLFI, combining a generative unsupervised physics-informed neural network (PINN) with a large FOV LFI setup for straightforward holographic image reconstruction, without multi-measurement. GenLFI enables real-time 2D imaging for 3D samples, such as droplet-based microfluidics and 3D cell models, in dynamic complex optical fields. Unlike previous methods, our approach decouples the reconstruction algorithm from optical setup parameters, enabling a large FOV limited only by hardware. We demonstrate a real-time FOV exceeding 550 mm$^2$, over 20 times larger than current real-time LFI systems. This framework unlocks the potential of LFI systems, providing a robust tool for advancing automated high-throughput biomedical applications.