Yanshu Wang

Jianwei Sun, Xiaoning Lei, Wenhao Cai et al.

Task-based measures of image quality (IQ) are critical for evaluating medical imaging systems, which must account for randomness including anatomical variability. Stochastic object models (SOMs) provide a statistical description of such variability, but conventional mathematical SOMs fail to capture realistic anatomy, while data-driven approaches typically require clean data rarely available in clinical tasks. To address this challenge, we propose AMID, an unsupervised Ambient Measurement-Integrated Diffusion with noise decoupling, which establishes clean SOMs directly from noisy measurements. AMID introduces a measurement-integrated strategy aligning measurement noise with the diffusion trajectory, and explicitly models coupling between measurement and diffusion noise across steps, an ambient loss is thus designed base on it to learn clean SOMs. Experiments on real CT and mammography datasets show that AMID outperforms existing methods in generation fidelity and yields more reliable task-based IQ evaluation, demonstrating its potential for unsupervised medical imaging analysis.

Xichen Xu, Yanshu Wang, Jinbao Wang et al.

Segmentation-oriented Industrial Anomaly Synthesis (SIAS) plays a pivotal role in enhancing the performance of downstream anomaly segmentation, as it provides an effective means of expanding abnormal data. However, existing SIAS methods face several critical limitations: (i) the synthesized anomalies often lack intricate texture details and fail to align precisely with the surrounding background, and (ii) they struggle to generate fine-grained, pixel-level anomalies. To address these challenges, we propose Segmentation-oriented Anomaly synthesis via Graded diffusion with Explicit mask alignment, termed STAGE. STAGE introduces a novel anomaly inference strategy that incorporates clean background information as a prior to guide the denoising distribution, enabling the model to more effectively distinguish and highlight abnormal foregrounds. Furthermore, it employs a graded diffusion framework with an anomaly-only branch to explicitly record local anomalies during both the forward and reverse processes, ensuring that subtle anomalies are not overlooked. Finally, STAGE incorporates the explicit mask alignment (EMA) strategy to progressively align the synthesized anomalies with the background, resulting in context-consistent and structurally coherent generations. Extensive experiments on the MVTec and BTAD datasets demonstrate that STAGE achieves state-of-the-art performance in SIAS, which in turn enhances downstream anomaly segmentation.

Yanshu Wang, Xichen Xu, Xiaoning Lei et al.

Synthesizing realistic and spatially precise anomalies is essential for enhancing the robustness of industrial anomaly detection systems. While recent diffusion-based methods have demonstrated strong capabilities in modeling complex defect patterns, they often struggle with spatial controllability and fail to maintain fine-grained regional fidelity. To overcome these limitations, we propose SARD (Segmentation-Aware anomaly synthesis via Region-constrained Diffusion with discriminative mask Guidance), a novel diffusion-based framework specifically designed for anomaly generation. Our approach introduces a Region-Constrained Diffusion (RCD) process that preserves the background by freezing it and selectively updating only the foreground anomaly regions during the reverse denoising phase, thereby effectively reducing background artifacts. Additionally, we incorporate a Discriminative Mask Guidance (DMG) module into the discriminator, enabling joint evaluation of both global realism and local anomaly fidelity, guided by pixel-level masks. Extensive experiments on the MVTec-AD and BTAD datasets show that SARD surpasses existing methods in segmentation accuracy and visual quality, setting a new state-of-the-art for pixel-level anomaly synthesis.