Helen Jones

Natalia Garcia Martin, Stefano Malacrino, Marta Wojciechowska et al.

Multiplexed immunofluorescence provides an unprecedented opportunity for studying specific cell-to-cell and cell microenvironment interactions. We employ graph neural networks to combine features obtained from tissue morphology with measurements of protein expression to profile the tumour microenvironment associated with different tumour stages. Our framework presents a new approach to analysing and processing these complex multi-dimensional datasets that overcomes some of the key challenges in analysing these data and opens up the opportunity to abstract biologically meaningful interactions.

Yifan Yang, Daniel Cooper, John Collomosse et al.

We present a novel blockchain based service for proving the provenance of online digital identity, exposed as an assistive tool to help non-expert users make better decisions about whom to trust online. Our service harnesses the digital personhood (DP); the longitudinal and multi-modal signals created through users' lifelong digital interactions, as a basis for evidencing the provenance of identity. We describe how users may exchange trust evidence derived from their DP, in a granular and privacy-preserving manner, with other users in order to demonstrate coherence and longevity in their behaviour online. This is enabled through a novel secure infrastructure combining hybrid on- and off-chain storage combined with deep learning for DP analytics and visualization. We show how our tools enable users to make more effective decisions on whether to trust unknown third parties online, and also to spot behavioural deviations in their own social media footprints indicative of account hijacking.