David Borland

David Borland, Irena Brain, Karamarie Fecho et al.

As the COVID-19 pandemic continues to impact the world, data is being gathered and analyzed to better understand the disease. Recognizing the potential for visual analytics technologies to support exploratory analysis and hypothesis generation from longitudinal clinical data, a team of collaborators worked to apply existing event sequence visual analytics technologies to a longitudinal clinical data from a cohort of 998 patients with high rates of COVID-19 infection. This paper describes the initial steps toward this goal, including: (1) the data transformation and processing work required to prepare the data for visual analysis, (2) initial findings and observations, and (3) qualitative feedback and lessons learned which highlight key features as well as limitations to address in future work.

Smiti Kaul, David Borland, Nan Cao et al.

Complex, high-dimensional data is used in a wide range of domains to explore problems and make decisions. Analysis of high-dimensional data, however, is vulnerable to the hidden influence of confounding variables, especially as users apply ad hoc filtering operations to visualize only specific subsets of an entire dataset. Thus, visual data-driven analysis can mislead users and encourage mistaken assumptions about causality or the strength of relationships between features. This work introduces a novel visual approach designed to reveal the presence of confounding variables via counterfactual possibilities during visual data analysis. It is implemented in CoFact, an interactive visualization prototype that determines and visualizes \textit{counterfactual subsets} to better support user exploration of feature relationships. Using publicly available datasets, we conducted a controlled user study to demonstrate the effectiveness of our approach; the results indicate that users exposed to counterfactual visualizations formed more careful judgments about feature-to-outcome relationships.

David Borland, Jonathan Zhang, Smiti Kaul et al.

The collection and visual analysis of large-scale data from complex systems, such as electronic health records or clickstream data, has become increasingly common across a wide range of industries. This type of retrospective visual analysis, however, is prone to a variety of selection bias effects, especially for high-dimensional data where only a subset of dimensions is visualized at any given time. The risk of selection bias is even higher when analysts dynamically apply filters or perform grouping operations during ad hoc analyses. These bias effects threatens the validity and generalizability of insights discovered during visual analysis as the basis for decision making. Past work has focused on bias transparency, helping users understand when selection bias may have occurred. However, countering the effects of selection bias via bias mitigation is typically left for the user to accomplish as a separate process. Dynamic reweighting (DR) is a novel computational approach to selection bias mitigation that helps users craft bias-corrected visualizations. This paper describes the DR workflow, introduces key DR visualization designs, and presents statistical methods that support the DR process. Use cases from the medical domain, as well as findings from domain expert user interviews, are also reported.

David Borland, Wenyuan Wang, Jonathan Zhang et al.

The collection of large, complex datasets has become common across a wide variety of domains. Visual analytics tools increasingly play a key role in exploring and answering complex questions about these large datasets. However, many visualizations are not designed to concurrently visualize the large number of dimensions present in complex datasets (e.g. tens of thousands of distinct codes in an electronic health record system). This fact, combined with the ability of many visual analytics systems to enable rapid, ad-hoc specification of groups, or cohorts, of individuals based on a small subset of visualized dimensions, leads to the possibility of introducing selection bias--when the user creates a cohort based on a specified set of dimensions, differences across many other unseen dimensions may also be introduced. These unintended side effects may result in the cohort no longer being representative of the larger population intended to be studied, which can negatively affect the validity of subsequent analyses. We present techniques for selection bias tracking and visualization that can be incorporated into high-dimensional exploratory visual analytics systems, with a focus on medical data with existing data hierarchies. These techniques include: (1) tree-based cohort provenance and visualization, with a user-specified baseline cohort that all other cohorts are compared against, and visual encoding of the drift for each cohort, which indicates where selection bias may have occurred, and (2) a set of visualizations, including a novel icicle-plot based visualization, to compare in detail the per-dimension differences between the baseline and a user-specified focus cohort. These techniques are integrated into a medical temporal event sequence visual analytics tool. We present example use cases and report findings from domain expert user interviews.

David Gotz, Jonathan Zhang, Wenyuan Wang et al.

Temporal event data are collected across a broad range of domains, and a variety of visual analytics techniques have been developed to empower analysts working with this form of data. These techniques generally display aggregate statistics computed over sets of event sequences that share common patterns. Such techniques are often hindered, however, by the high-dimensionality of many real-world event sequence datasets because the large number of distinct event types within such data prevents effective aggregation. A common coping strategy for this challenge is to group event types together as a pre-process, prior to visualization, so that each group can be represented within an analysis as a single event type. However, computing these event groupings as a pre-process also places significant constraints on the analysis. This paper presents a dynamic hierarchical aggregation technique that leverages a predefined hierarchy of dimensions to computationally quantify the informativeness of alternative levels of grouping within the hierarchy at runtime. This allows users to dynamically explore the hierarchy to select the most appropriate level of grouping to use at any individual step within an analysis. Key contributions include an algorithm for interactively determining the most informative set of event groupings from within a large-scale hierarchy of event types, and a scatter-plus-focus visualization that supports interactive hierarchical exploration. While these contributions are generalizable to other types of problems, we apply them to high-dimensional event sequence analysis using large-scale event type hierarchies from the medical domain. We describe their use within a medical cohort analysis tool called Cadence, demonstrate an example in which the proposed technique supports better views of event sequence data, and report findings from domain expert interviews.