Abdelrahman Elsayed

Abdelrahman Elsayed, Ahmed Jaheen, Mohammad Yaqub

Automated brain tumor segmentation in multi-parametric MRI remains challenging in resource-constrained settings where deep 3D networks are computationally prohibitive. We propose MMRINet, a lightweight architecture that replaces quadratic-complexity attention with linear-complexity Mamba state-space models for efficient volumetric context modeling. Novel Dual-Path Feature Refinement (DPFR) modules maximize feature diversity without additional data requirements, while Progressive Feature Aggregation (PFA) enables effective multi-scale fusion. In the BraTS-Lighthouse SSA 2025, our model achieves strong performance with an average Dice score of (0.752) and an average HD95 of (12.23) with only ~2.5M parameters, demonstrating efficient and accurate segmentation suitable for low-resource clinical environments. Our GitHub repository can be accessed here: github.com/BioMedIA-MBZUAI/MMRINet.

Ahmed Jaheen, Abdelrahman Elsayed, Damir Kim et al.

Brain cancer affects millions worldwide, and in nearly every clinical setting, doctors rely on magnetic resonance imaging (MRI) to diagnose and monitor gliomas. However, the current standard for tumor quantification through manual segmentation of multi-parametric MRI is time-consuming, requires expert radiologists, and is often infeasible in under-resourced healthcare systems. This problem is especially pronounced in low-income regions, where MRI scanners are of lower quality and radiology expertise is scarce, leading to incorrect segmentation and quantification. In addition, the number of acquired MRI scans in Africa is typically small. To address these challenges, the BraTS-Lighthouse 2025 Challenge focuses on robust tumor segmentation in sub-Saharan Africa (SSA), where resource constraints and image quality degradation introduce significant shifts. In this study, we present EMedNeXt -- an enhanced brain tumor segmentation framework based on MedNeXt V2 with deep supervision and optimized post-processing pipelines tailored for SSA. EMedNeXt introduces three key contributions: a larger region of interest, an improved nnU-Net v2-based architectural skeleton, and a robust model ensembling system. Evaluated on the hidden validation set, our solution achieved an average LesionWise DSC of 0.897 with an average LesionWise NSD of 0.541 and 0.84 at a tolerance of 0.5 mm and 1.0 mm, respectively.

Mohamed Gamil, Abdelrahman Elsayed, Abdelrahman Lila et al.

Despite recent advances in AI, multimodal culturally diverse datasets are still limited, particularly for regions in the Middle East and Africa. In this paper, we introduce EgMM-Corpus, a multimodal dataset dedicated to Egyptian culture. By designing and running a new data collection pipeline, we collected over 3,000 images, covering 313 concepts across landmarks, food, and folklore. Each entry in the dataset is manually validated for cultural authenticity and multimodal coherence. EgMM-Corpus aims to provide a reliable resource for evaluating and training vision-language models in an Egyptian cultural context. We further evaluate the zero-shot performance of Contrastive Language-Image Pre-training CLIP on EgMM-Corpus, on which it achieves 21.2% Top-1 accuracy and 36.4% Top-5 accuracy in classification. These results underscore the existing cultural bias in large-scale vision-language models and demonstrate the importance of EgMM-Corpus as a benchmark for developing culturally aware models.

Daniil Tikhonov, Matheus Scatolin, Mohor Banerjee et al.

Accurate evaluation of the response of glioblastoma to therapy is crucial for clinical decision-making and patient management. The Response Assessment in Neuro-Oncology (RANO) criteria provide a standardized framework to assess patients' clinical response, but their application can be complex and subject to observer variability. This paper presents an automated method for classifying the intervention response from longitudinal MRI scans, developed to predict tumor response during therapy as part of the BraTS 2025 challenge. We propose a novel hybrid framework that combines deep learning derived feature extraction and an extensive set of radiomics and clinically chosen features. Our approach utilizes a fine-tuned ResNet-18 model to extract features from 2D regions of interest across four MRI modalities. These deep features are then fused with a rich set of more than 4800 radiomic and clinically driven features, including 3D radiomics of tumor growth and shrinkage masks, volumetric changes relative to the nadir, and tumor centroid shift. Using the fused feature set, a CatBoost classifier achieves a mean ROC AUC of 0.81 and a Macro F1 score of 0.50 in the 4-class response prediction task (Complete Response, Partial Response, Stable Disease, Progressive Disease). Our results highlight that synergizing learned image representations with domain-targeted radiomic features provides a robust and effective solution for automated treatment response assessment in neuro-oncology.

Abdelrahman Elsayed, Hoda M. O. Mokhtar, Osama Ismail

Nowadays, document clustering is considered as a data intensive task due to the dramatic, fast increase in the number of available documents. Nevertheless, the features that represent those documents are also too large. The most common method for representing documents is the vector space model, which represents document features as a bag of words and does not represent semantic relations between words. In this paper we introduce a distributed implementation for the bisecting k-means using MapReduce programming model. The aim behind our proposed implementation is to solve the problem of clustering intensive data documents. In addition, we propose integrating the WordNet ontology with bisecting k-means in order to utilize the semantic relations between words to enhance document clustering results. Our presented experimental results show that using lexical categories for nouns only enhances internal evaluation measures of document clustering; and decreases the documents features from thousands to tens features. Our experiments were conducted using Amazon Elastic MapReduce to deploy the Bisecting k-means algorithm.