Xiang Chen

Xiang Chen, Yan Xia, Nishant Ravikumar et al.

Medical image registration is a challenging task involving the estimation of spatial transformations to establish anatomical correspondence between pairs or groups of images. Recently, deep learning-based image registration methods have been widely explored, and demonstrated to enable fast and accurate image registration in a variety of applications. However, most deep learning-based registration methods assume that the deformation fields are smooth and continuous everywhere in the image domain, which is not always true, especially when registering images whose fields of view contain discontinuities at tissue/organ boundaries. In such scenarios, enforcing smooth, globally continuous deformation fields leads to incorrect/implausible registration results. We propose a novel discontinuity-preserving image registration method to tackle this challenge, which ensures globally discontinuous and locally smooth deformation fields, leading to more accurate and realistic registration results. The proposed method leverages the complementary nature of image segmentation and registration and enables joint segmentation and pair-wise registration of images. A co-attention block is proposed in the segmentation component of the network to learn the structural correlations in the input images, while a discontinuity-preserving registration strategy is employed in the registration component of the network to ensure plausibility in the estimated deformation fields at tissue/organ interfaces. We evaluate our method on the task of intra-subject spatio-temporal image registration using large-scale cinematic cardiac magnetic resonance image sequences, and demonstrate that our method achieves significant improvements over the state-of-the-art for medical image registration, and produces high-quality segmentation masks for the regions of interest.

Xiang Chen, Jinshan Pan, Jiangxin Dong

How to effectively explore multi-scale representations of rain streaks is important for image deraining. In contrast to existing Transformer-based methods that depend mostly on single-scale rain appearance, we develop an end-to-end multi-scale Transformer that leverages the potentially useful features in various scales to facilitate high-quality image reconstruction. To better explore the common degradation representations from spatially-varying rain streaks, we incorporate intra-scale implicit neural representations based on pixel coordinates with the degraded inputs in a closed-loop design, enabling the learned features to facilitate rain removal and improve the robustness of the model in complex scenarios. To ensure richer collaborative representation from different scales, we embed a simple yet effective inter-scale bidirectional feedback operation into our multi-scale Transformer by performing coarse-to-fine and fine-to-coarse information communication. Extensive experiments demonstrate that our approach, named as NeRD-Rain, performs favorably against the state-of-the-art ones on both synthetic and real-world benchmark datasets. The source code and trained models are available at https://github.com/cschenxiang/NeRD-Rain.

Xiang Chen, Nishant Ravikumar, Yan Xia et al.

Image registration aims to establish spatial correspondence across pairs, or groups of images, and is a cornerstone of medical image computing and computer-assisted-interventions. Currently, most deep learning-based registration methods assume that the desired deformation fields are globally smooth and continuous, which is not always valid for real-world scenarios, especially in medical image registration (e.g. cardiac imaging and abdominal imaging). Such a global constraint can lead to artefacts and increased errors at discontinuous tissue interfaces. To tackle this issue, we propose a weakly-supervised Deep Discontinuity-preserving Image Registration network (DDIR), to obtain better registration performance and realistic deformation fields. We demonstrate that our method achieves significant improvements in registration accuracy and predicts more realistic deformations, in registration experiments on cardiac magnetic resonance (MR) images from UK Biobank Imaging Study (UKBB), than state-of-the-art approaches.

Xiang Chen, Yan Xia, Nishant Ravikumar et al.

Image registration is a fundamental building block for various applications in medical image analysis. To better explore the correlation between the fixed and moving images and improve registration performance, we propose a novel deep learning network, Co-Attention guided Registration Network (CAR-Net). CAR-Net employs a co-attention block to learn a new representation of the inputs, which drives the registration of the fixed and moving images. Experiments on UK Biobank cardiac cine-magnetic resonance image data demonstrate that CAR-Net obtains higher registration accuracy and smoother deformation fields than state-of-the-art unsupervised registration methods, while achieving comparable or better registration performance than corresponding weakly-supervised variants. In addition, our approach can provide critical structural information of the input fixed and moving images simultaneously in a completely unsupervised manner.

Xiang Chen, Lingbo Qing, Xiaohai He et al.

As a sub-domain of text-to-image synthesis, text-to-face generation has huge potentials in public safety domain. With lack of dataset, there are almost no related research focusing on text-to-face synthesis. In this paper, we propose a fully-trained Generative Adversarial Network (FTGAN) that trains the text encoder and image decoder at the same time for fine-grained text-to-face generation. With a novel fully-trained generative network, FTGAN can synthesize higher-quality images and urge the outputs of the FTGAN are more relevant to the input sentences. In addition, we build a dataset called SCU-Text2face for text-to-face synthesis. Through extensive experiments, the FTGAN shows its superiority in boosting both generated images' quality and similarity to the input descriptions. The proposed FTGAN outperforms the previous state of the art, boosting the best reported Inception Score to 4.63 on the CUB dataset. On SCU-text2face, the face images generated by our proposed FTGAN just based on the input descriptions is of average 59% similarity to the ground-truth, which set a baseline for text-to-face synthesis.