Leire Benito-Del-Valle

Artzai Picon, Pablo Galan, Arantza Bereciartua-Perez et al.

Hyperspectral imaging, a rapidly evolving field, has witnessed the ascendancy of deep learning techniques, supplanting classical feature extraction and classification methods in various applications. However, many researchers employ arbitrary architectures for hyperspectral image processing, often without rigorous analysis of the interplay between spectral and spatial information. This oversight neglects the implications of combining these two modalities on model performance. In this paper, we evaluate the performance of diverse deep learning architectures for hyperspectral image segmentation. Our analysis disentangles the impact of different architectures, spanning various spectral and spatial granularities. Specifically, we investigate the effects of spectral resolution (capturing spectral information) and spatial texture (conveying spatial details) on segmentation outcomes. Additionally, we explore the transferability of knowledge from large pre-trained image foundation models, originally designed for RGB images, to the hyperspectral domain. Results show that incorporating spatial information alongside spectral data leads to improved segmentation results, and that it is essential to further work on novel architectures comprising spectral and spatial information and on the adaption of RGB foundation models into the hyperspectral domain. Furthermore, we contribute to the field by cleaning and publicly releasing the Tecnalia WEEE Hyperspectral dataset. This dataset contains different non-ferrous fractions of Waste Electrical and Electronic Equipment (WEEE), including Copper, Brass, Aluminum, Stainless Steel, and White Copper, spanning the range of 400 to 1000 nm. We expect these conclusions can guide novel researchers in the field of hyperspectral imaging.

Leire Benito-Del-Valle, Aitor Alvarez-Gila, Itziar Eguskiza et al.

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need for expert annotations and ethical constraints. To address this, we examine the suitability of different generative models and image selection approaches to create realistic synthetic histopathology image patches conditioned on class labels. Our findings highlight the importance of selecting an appropriate generative model type and architecture to enhance performance. Our experiments over the PCam dataset show that diffusion models are effective for transfer learning, while GAN-generated samples are better suited for augmentation. Additionally, transformer-based generative models do not require image filtering, in contrast to those derived from Convolutional Neural Networks (CNNs), which benefit from realism score-based selection. Therefore, we show that synthetic images can effectively augment existing datasets, ultimately improving the performance of the downstream histopathology image classification task.

Leire Benito-Del-Valle, Artzai Picón, Daniel Mugica et al.

Herbicide field trials require accurate identification of plant species and assessment of herbicide-induced damage across diverse environments. While general-purpose vision foundation models have shown promising results in complex visual domains, their performance can be limited in agriculture, where fine-grained distinctions between species and damage types are critical. In this work, we adapt a general-purpose vision foundation model to herbicide trial characterization. Trained using a self-supervised learning approach on a large, curated agricultural dataset, the model learns rich and transferable representations optimized for herbicide trials images. Our domain-specific model significantly outperforms the best general-purpose foundation model in both species identification (F1 score improvement from 0.91 to 0.94) and damage classification (from 0.26 to 0.33). Under unseen conditions (new locations and other time), it achieves even greater gains (species identification from 0.56 to 0.66; damage classification from 0.17 to 0.27). In domain-shift scenarios, such as drone imagery, it maintains strong performance (species classification from 0.49 to 0.60). Additionally, we show that domain-specific pretraining enhances segmentation accuracy, particularly in low-annotation regimes. An annotation-efficiency analysis reveals that, under unseen conditions, the domain-specific model achieves 5.4% higher F1 score than the general-purpose model, while using 80% fewer labeled samples. These results demonstrate the generalization capabilities of domain-specific foundation models and their potential to significantly reduce manual annotation efforts, offering a scalable and automated solution for herbicide trial analysis.

Leire Benito-Del-Valle, Pedro A. Moreno-Sánchez, Itziar Egusquiza et al.

The MIDOG 2025 challenge extends prior work on mitotic figure detection by introducing a new Track 2 on atypical mitosis classification. This task aims to distinguish normal from atypical mitotic figures in histopathology images, a clinically relevant but highly imbalanced and cross-domain problem. We investigated two complementary backbones: (i) ConvNeXt-Small, pretrained on ImageNet, and (ii) a histopathology-specific ViT from Lunit trained via self-supervision. To address the strong prevalence imbalance (9408 normal vs. 1741 atypical), we synthesized additional atypical examples to approximate class balance and compared models trained with real-only vs. real+synthetic data. Using five-fold cross-validation, both backbones reached strong performance (mean AUROC approximately 95 percent), with ConvNeXt achieving slightly higher peaks while Lunit exhibited greater fold-to-fold stability. Synthetic balancing, however, did not lead to consistent improvements. On the organizers' preliminary hidden test set, explicitly designed as an out-of-distribution debug subset, ConvNeXt attained the highest AUROC (95.4 percent), whereas Lunit remained competitive on balanced accuracy. These findings suggest that both ImageNet and domain-pretrained backbones are viable for atypical mitosis classification, with domain-pretraining conferring robustness and ImageNet pretraining reaching higher peaks, while naive synthetic balancing has limited benefit. Full hidden test set results will be reported upon challenge completion.

Uxue Delaquintana-Aramendi, Leire Benito-del-Valle, Aitor Alvarez-Gila et al.

In colonoscopy, 80% of the missed polyps could be detected with the help of Deep Learning models. In the search for algorithms capable of addressing this challenge, foundation models emerge as promising candidates. Their zero-shot or few-shot learning capabilities, facilitate generalization to new data or tasks without extensive fine-tuning. A concept that is particularly advantageous in the medical imaging domain, where large annotated datasets for traditional training are scarce. In this context, a comprehensive evaluation of foundation models for polyp segmentation was conducted, assessing both detection and delimitation. For the study, three different colonoscopy datasets have been employed to compare the performance of five different foundation models, DINOv2, YOLO-World, GroundingDINO, SAM and MedSAM, against two benchmark networks, YOLOv8 and Mask R-CNN. Results show that the success of foundation models in polyp characterization is highly dependent on domain specialization. For optimal performance in medical applications, domain-specific models are essential, and generic models require fine-tuning to achieve effective results. Through this specialization, foundation models demonstrated superior performance compared to state-of-the-art detection and segmentation models, with some models even excelling in zero-shot evaluation; outperforming fine-tuned models on unseen data.