Yuanpeng Zhang

Jiabao Sheng, Yuanpeng Zhang, Jing Cai et al.

The prediction of adaptive radiation therapy (ART) prior to radiation therapy (RT) for nasopharyngeal carcinoma (NPC) patients is important to reduce toxicity and prolong the survival of patients. Currently, due to the complex tumor micro-environment, a single type of high-resolution image can provide only limited information. Meanwhile, the traditional softmax-based loss is insufficient for quantifying the discriminative power of a model. To overcome these challenges, we propose a supervised multi-view contrastive learning method with an additive margin (MMCon). For each patient, four medical images are considered to form multi-view positive pairs, which can provide additional information and enhance the representation of medical images. In addition, the embedding space is learned by means of contrastive learning. NPC samples from the same patient or with similar labels will remain close in the embedding space, while NPC samples with different labels will be far apart. To improve the discriminative ability of the loss function, we incorporate a margin into the contrastive learning. Experimental result show this new learning objective can be used to find an embedding space that exhibits superior discrimination ability for NPC images.

Chenhao Xue, Yukun Wang, An Guo et al.

SRAM-based compute-in-memory (CIM) offers high computational density and energy efficiency for deep neural network (DNN) accelerators, but its limited capacity causes on/off-chip data movement overhead for large DNN models. Existing CIM accelerator studies typically assume that DNN models fit entirely on-chip, leaving efficient dataflow design largely untapped. This paper introduces AccelCIM, a systematic dataflow exploration framework for SRAM CIM accelerator, which addresses two key limitations of prior work. (1) It formulates a systematic dataflow design space spanning CIM macro configurations and macro-array organizations. (2) It introduces rigorous design evaluation using cycle-accurate architectural simulation and post-layout PPA analysis. We conduct an extensive design space exploration and apply AccelCIM to representative LLM applications, providing practical insights for the principled design of CIM accelerators.

Yuanpeng Zhang, Xing Hu, Xi Chen et al.

SRAM Processing-in-Memory (PIM) has emerged as the most promising implementation for high-performance PIM, delivering superior computing density, energy efficiency, and computational precision. However, the pursuit of higher performance necessitates more complex circuit designs and increased operating frequencies, which exacerbate IR-drop issues. Severe IR-drop can significantly degrade chip performance and even threaten reliability. Conventional circuit-level IR-drop mitigation methods, such as back-end optimizations, are resource-intensive and often compromise power, performance, and area (PPA). To address these challenges, we propose AIM, comprehensive software and hardware co-design for architecture-level IR-drop mitigation in high-performance PIM. Initially, leveraging the bit-serial and in-situ dataflow processing properties of PIM, we introduce Rtog and HR, which establish a direct correlation between PIM workloads and IR-drop. Building on this foundation, we propose LHR and WDS, enabling extensive exploration of architecture-level IR-drop mitigation while maintaining computational accuracy through software optimization. Subsequently, we develop IR-Booster, a dynamic adjustment mechanism that integrates software-level HR information with hardware-based IR-drop monitoring to adapt the V-f pairs of the PIM macro, achieving enhanced energy efficiency and performance. Finally, we propose the HR-aware task mapping method, bridging software and hardware designs to achieve optimal improvement. Post-layout simulation results on a 7nm 256-TOPS PIM chip demonstrate that AIM achieves up to 69.2% IR-drop mitigation, resulting in 2.29x energy efficiency improvement and 1.152x speedup.

Jiabao Sheng, SaiKit Lam, Jiang Zhang et al.

Omics fusion has emerged as a crucial preprocessing approach in the field of medical image processing, providing significant assistance to several studies. One of the challenges encountered in the integration of omics data is the presence of unpredictability arising from disparities in data sources and medical imaging equipment. In order to overcome this challenge and facilitate the integration of their joint application to specific medical objectives, this study aims to develop a fusion methodology that mitigates the disparities inherent in omics data. The utilization of the multi-kernel late-fusion method has gained significant popularity as an effective strategy for addressing this particular challenge. An efficient representation of the data may be achieved by utilizing a suitable single-kernel function to map the inherent features and afterward merging them in a space with a high number of dimensions. This approach effectively addresses the differences noted before. The inflexibility of label fitting poses a constraint on the use of multi-kernel late-fusion methods in complex nasopharyngeal carcinoma (NPC) datasets, hence affecting the efficacy of general classifiers in dealing with high-dimensional characteristics. This innovative methodology aims to increase the disparity between the two cohorts, hence providing a more flexible structure for the allocation of labels. The examination of the NPC-ContraParotid dataset demonstrates the model's robustness and efficacy, indicating its potential as a valuable tool for predicting distant metastases in patients with nasopharyngeal carcinoma (NPC).

Wei Zhang, Zi Wang, Hanwen Zhou et al.

A reliable evaluation of surgical difficulty can improve the success of the treatment for rectal cancer and the current evaluation method is based on clinical data. However, more data about rectal cancer can be collected with the development of technology. Meanwhile, with the development of artificial intelligence, its application in rectal cancer treatment is becoming possible. In this paper, a multi-view rectal cancer dataset is first constructed to give a more comprehensive view of patients, including the high-resolution MRI image view, pressed-fat MRI image view, and clinical data view. Then, an interpretable incomplete multi-view surgical evaluation model is proposed, considering that it is hard to obtain extensive and complete patient data in real application scenarios. Specifically, a dual representation incomplete multi-view learning model is first proposed to extract the common information between views and specific information in each view. In this model, the missing view imputation is integrated into representation learning, and second-order similarity constraint is also introduced to improve the cooperative learning between these two parts. Then, based on the imputed multi-view data and the learned dual representation, a multi-view surgical evaluation model with the TSK fuzzy system is proposed. In the proposed model, a cooperative learning mechanism is constructed to explore the consistent information between views, and Shannon entropy is also introduced to adapt the view weight. On the MVRC dataset, we compared it with several advanced algorithms and DRIMV_TSK obtained the best results.