Konstantinos Vrettos

Konstantinos Vrettos, Galini Papadaki, Emmanouil Brilakis et al.

The rapid developments in artificial intelligence (AI) research in radiology have produced numerous models that are scattered across various platforms and sources, limiting discoverability, reproducibility and clinical translation. Herein, OpenRad was created, a curated, standardized, open-access repository that aggregates radiology AI models and providing details such as the availability of pretrained weights and interactive applications. Retrospective analysis of peer reviewed literature and preprints indexed in PubMed, arXiv and Scopus was performed until Dec 2025 (n = 5239 records). Model records were generated using a locally hosted LLM (gpt-oss:120b), based on the RSNA AI Roadmap JSON schema, and manually verified by ten expert reviewers. Stability of LLM outputs was assessed on 225 randomly selected papers using text similarity metrics. A total of 1694 articles were included after review. Included models span all imaging modalities (CT, MRI, X-ray, US) and radiology subspecialties. Automated extraction demonstrated high stability for structured fields (Levenshtein ratio > 90%), with 78.5% of record edits being characterized as minor during expert review. Statistical analysis of the repository revealed CNN and transformer architectures as dominant, while MRI was the most commonly used modality (in 621 neuroradiology AI models). Research output was mostly concentrated in China and the United States. The OpenRad web interface enables model discovery via keyword search and filters for modality, subspecialty, intended use, verification status and demo availability, alongside live statistics. The community can contribute new models through a dedicated portal. OpenRad contains approx. 1700 open access, curated radiology AI models with standardized metadata, supplemented with analysis of code repositories, thereby creating a comprehensive, searchable resource for the radiology community.

Konstantinos Vrettos, Michail E. Klontzas

Background The increasing adoption of Artificial Intelligence (AI) in healthcare has sparked growing concerns about its environmental and ethical implications. Commercial Large Language Models (LLMs), such as ChatGPT and DeepSeek, require substantial resources, while the utilization of these systems for medical purposes raises critical issues regarding patient privacy and safety. Methods We developed a customizable Retrieval-Augmented Generation (RAG) framework for medical tasks, which monitors its energy usage and CO2 emissions. This system was then used to create RAGs based on various open-source LLMs. The tested models included both general purpose models like llama3.1:8b and medgemma-4b-it, which is medical-domain specific. The best RAGs performance and energy consumption was compared to DeepSeekV3-R1 and OpenAIs o4-mini model. A dataset of medical questions was used for the evaluation. Results Custom RAG models outperformed commercial models in accuracy and energy consumption. The RAG model built on llama3.1:8B achieved the highest accuracy (58.5%) and was significantly better than other models, including o4-mini and DeepSeekV3-R1. The llama3.1-RAG also exhibited the lowest energy consumption and CO2 footprint among all models, with a Performance per kWh of 0.52 and a total CO2 emission of 473g. Compared to o4-mini, the llama3.1-RAG achieved 2.7x times more accuracy points per kWh and 172% less electricity usage while maintaining higher accuracy. Conclusion Our study demonstrates that local LLMs can be leveraged to develop RAGs that outperform commercial, online LLMs in medical tasks, while having a smaller environmental impact. Our modular framework promotes sustainable AI development, reducing electricity usage and aligning with the UNs Sustainable Development Goals.