A. Fedorov

Y. Ye, R. D. Boyce, M. K. Davis et al.

The Sustainability and Industry Partnership Work Group (SIP-WG) is a part of the National Cancer Institute Informatics Technology for Cancer Research (ITCR) program. The charter of the SIP-WG is to investigate options of long-term sustainability of open source software (OSS) developed by the ITCR, in part by developing a collection of business model archetypes that can serve as sustainability plans for ITCR OSS development initiatives. The workgroup assembled models from the ITCR program, from other studies, and via engagement of its extensive network of relationships with other organizations (e.g., Chan Zuckerberg Initiative, Open Source Initiative and Software Sustainability Institute). This article reviews existing sustainability models and describes ten OSS use cases disseminated by the SIP-WG and others, and highlights five essential attributes (alignment with unmet scientific needs, dedicated development team, vibrant user community, feasible licensing model, and sustainable financial model) to assist academic software developers in achieving best practice in software sustainability.

U. Mahmood, M. M. Rahman, A. Fedorov et al.

Differentiating multivariate dynamic signals is a difficult learning problem as the feature space may be large yet often only a few training examples are available. Traditional approaches to this problem either proceed from handcrafted features or require large datasets to combat the m >> n problem. In this paper, we show that the source of the problem---signal dynamics---can be used to our advantage and noticeably improve classification performance on a range of discrimination tasks when training data is scarce. We demonstrate that self-supervised pre-training guided by signal dynamics produces embedding that generalizes across tasks, datasets, data collection sites, and data distributions. We perform an extensive evaluation of this approach on a range of tasks including simulated data, keyword detection problem, and a range of functional neuroimaging data, where we show that a single embedding learnt on healthy subjects generalizes across a number of disorders, age groups, and datasets.